Endoplasmic reticulum stress in the pathogenesis of early-onset pre-eclampsia

por Burton, Graham J., Yung, Hong-Wa
Publicado 2011

Elevated homocysteine activates unfolded protein responses and causes aberrant trophoblast differentiation and mouse blastocyst development

por Capatina, Nadejda, Burton, Graham J., Yung, Hong Wa
Publicado 2022

Protocol for culturing the endocrine junctional zone of the mouse placenta in serum-free medium

por Yung, Hong Wa, Burton, Graham J., Charnock-Jones, D. Stephen
Publicado 2023

Regulation of AKT Phosphorylation at Ser473 and Thr308 by Endoplasmic Reticulum Stress Modulates Substrate Specificity in a Severity Dependent Manner

por Yung, Hong Wa, Charnock-Jones, D. Stephen, Burton, Graham J.
Publicado 2011

Evidence of endoplasmic reticulum stress and protein synthesis inhibition in the placenta of non-native women at high altitude

por Yung, Hong Wa, Cox, Mathew, Tissot van Patot, Martha, Burton, Graham J.
Publicado 2012

Morphological and molecular changes in the murine placenta exposed to normobaric hypoxia throughout pregnancy

por Matheson, Hannah, Veerbeek, Jan H. W., Charnock‐Jones, D. Stephen, Burton, Graham J., Yung, Hong Wa
Publicado 2015

Differential activation of placental unfolded protein response pathways implies heterogeneity in causation of early- and late-onset pre-eclampsia

por Yung, Hong Wa, Atkinson, Daniel, Campion-Smith, Tim, Olovsson, Matts, Charnock-Jones, D Stephen, Burton, Graham J
Publicado 2014

Placental endoplasmic reticulum stress negatively regulates transcription of placental growth factor via ATF4 and ATF6β: implications for the pathophysiology of human pregnancy com...

por Mizuuchi, Masahito, Cindrova‐Davies, Tereza, Olovsson, Matts, Charnock‐Jones, D Stephen, Burton, Graham J, Yung, Hong Wa
Publicado 2016

Noncanonical mitochondrial unfolded protein response impairs placental oxidative phosphorylation in early-onset preeclampsia

por Yung, Hong Wa, Colleoni, Francesca, Dommett, Emilie, Cindrova-Davies, Tereza, Kingdom, John, Murray, Andrew J., Burton, Graham J.
Publicado 2019

Role of Endoplasmic Reticulum Stress in Proinflammatory Cytokine–Mediated Inhibition of Trophoblast Invasion in Placenta-Related Complications of Pregnancy

por Lee, Cheuk-Lun, Veerbeek, Jan H.W., Rana, Tirtha K., van Rijn, Bas B., Burton, Graham J., Yung, Hong Wa
Publicado 2019

Defective folate metabolism causes germline epigenetic instability and distinguishes Hira as a phenotype inheritance biomarker

por Blake, Georgina E. T., Zhao, Xiaohui, Yung, Hong wa, Burton, Graham J., Ferguson-Smith, Anne C., Hamilton, Russell S., Watson, Erica D.
Publicado 2021

Placental endoplasmic reticulum stress in gestational diabetes: the potential for therapeutic intervention with chemical chaperones and antioxidants

por Yung, Hong-wa, Alnæs-Katjavivi, Patji, Jones, Carolyn J. P., El-Bacha, Tatiana, Golic, Michaela, Staff, Anne-Cathrine, Burton, Graham J.
Publicado 2016

Suppression of Mitochondrial Electron Transport Chain Function in the Hypoxic Human Placenta: A Role for miRNA-210 and Protein Synthesis Inhibition

por Colleoni, Francesca, Padmanabhan, Nisha, Yung, Hong-wa, Watson, Erica D., Cetin, Irene, Tissot van Patot, Martha C., Burton, Graham J., Murray, Andrew J.
Publicado 2013

Endoplasmic reticulum stress disrupts placental morphogenesis: implications for human intrauterine growth restriction

por Yung, Hong wa, Hemberger, Myriam, Watson, Erica D, Senner, Claire E, Jones, Carolyn P, Kaufman, Randal J, Charnock-Jones, D Stephen, Burton, Graham J
Publicado 2012

Endothelin-1 down-regulates matrix metalloproteinase 14 and 15 expression in human first trimester trophoblasts via endothelin receptor type B

por Majali-Martinez, Alejandro, Velicky, Philipp, Pollheimer, Jürgen, Knöfler, Martin, Yung, Hong wa, Burton, Graham J., Tabrizi-Wizsy, Nassim Ghaffari, Lang, Uwe, Hiden, Ursula, Desoye, Gernot, Dieber-Rotheneder, Martina
Publicado 2017

Perturbation of placental protein glycosylation by endoplasmic reticulum stress promotes maladaptation of maternal hepatic glucose metabolism

por Yung, Hong Wa, Zhao, Xiaohui, Glover, Luke, Burrin, Charlotte, Pang, Poh-Choo, Jones, Carolyn J.P., Gill, Carolyn, Duhig, Kate, Olovsson, Matts, Chappell, Lucy C., Haslam, Stuart M., Dell, Anne, Burton, Graham J., Charnock-Jones, D. Stephen
Publicado 2022

The Residual Innate Lymphoid Cells in NFIL3-Deficient Mice Support Suboptimal Maternal Adaptations to Pregnancy

por Boulenouar, Selma, Doisne, Jean-Marc, Sferruzzi-Perri, Amanda, Gaynor, Louise M., Kieckbusch, Jens, Balmas, Elisa, Yung, Hong Wa, Javadzadeh, Shagayegh, Volmer, Léa, Hawkes, Delia A., Phillips, Keli, Brady, Hugh J.M., Fowden, Abigail L., Burton, Graham J., Moffett, Ashley, Colucci, Francesco
Publicado 2016

Placental Adaptation to Early-Onset Hypoxic Pregnancy and Mitochondria-Targeted Antioxidant Therapy in a Rodent Model

por Nuzzo, Anna M., Camm, Emily J., Sferruzzi-Perri, Amanda N., Ashmore, Thomas J., Yung, Hong-wa, Cindrova-Davies, Tereza, Spiroski, Ana-Mishel, Sutherland, Megan R., Logan, Angela, Austin-Williams, Shani, Burton, Graham J., Rolfo, Alessandro, Todros, Tullia, Murphy, Michael P., Giussani, Dino A.
Publicado 2018

Disturbed Placental Imprinting in Preeclampsia Leads to Altered Expression of DLX5, a Human-Specific Early Trophoblast Marker

por Zadora, Julianna, Singh, Manvendra, Herse, Florian, Przybyl, Lukasz, Haase, Nadine, Golic, Michaela, Yung, Hong Wa, Huppertz, Berthold, Cartwright, Judith E., Whitley, Guy, Johnsen, Guro M., Levi, Giovanni, Isbruch, Annette, Schulz, Herbert, Luft, Friedrich C., Müller, Dominik N., Staff, Anne Cathrine, Hurst, Laurence D., Dechend, Ralf, Izsvák, Zsuzsanna
Publicado 2017

Chronic Hypoxia in Ovine Pregnancy Recapitulates Physiological and Molecular Markers of Preeclampsia in the Mother, Placenta, and Offspring

por Tong, Wen, Allison, Beth J., Brain, Kirsty L., Patey, Olga V., Niu, Youguo, Botting, Kimberley J., Ford, Sage G., Garrud, Tessa A., Wooding, Peter F.B., Shaw, Caroline J., Lyu, Qiang, Zhang, Lin, Ma, Jin, Cindrova-Davies, Tereza, Yung, Hong Wa, Burton, Graham J., Giussani, Dino A.
Publicado 2022