Elevated de novo protein synthesis in FMRP-deficient human neurons and its correction by metformin treatment

por Utami, Kagistia Hana, Yusof, Nur Amirah Binte Mohammad, Kwa, Jing Eugene, Peteri, Ulla-Kaisa, Castrén, Maija L., Pouladi, Mahmoud A.
Publicado 2020

Widespread dysregulation of mRNA splicing implicates RNA processing in the development and progression of Huntington's disease

por Tano, Vincent, Utami, Kagistia Hana, Yusof, Nur Amirah Binte Mohammad, Bégin, Jocelyn, Tan, Willy Wei Li, Pouladi, Mahmoud A., Langley, Sarah R.
Publicado 2023

pS421 huntingtin modulates mitochondrial phenotypes and confers neuroprotection in an HD hiPSC model

por Xu, Xiaohong, Ng, Bryan, Sim, Bernice, Radulescu, Carola I., Yusof, Nur Amirah Binte Mohammad, Goh, Wah Ing, Lin, Shuping, Lim, John Soon Yew, Cha, Yoonjeong, Kusko, Rebecca, Kay, Chris, Ratovitski, Tamara, Ross, Christopher, Hayden, Michael R., Wright, Graham, Pouladi, Mahmoud A.
Publicado 2020

Ermin deficiency leads to compromised myelin, inflammatory milieu, and susceptibility to demyelinating insult

por Ziaei, Amin, Garcia‐Miralles, Marta, Radulescu, Carola I., Sidik, Harwin, Silvin, Aymeric, Bae, Han‐Gyu, Bonnard, Carine, Yusof, Nur Amirah Binte Mohammad, Ferrari Bardile, Costanza, Tan, Liang Juin, Ng, Alvin Yu Jin, Tohari, Sumanty, Dehghani, Leila, Henry, Lily, Yeo, Xin Yi, Lee, Sejin, Venkatesh, Byrappa, Langley, Sarah R., Shaygannejad, Vahid, Reversade, Bruno, Jung, Sangyong, Ginhoux, Florent, Pouladi, Mahmoud A.
Publicado 2022