RNA-targeted small-molecule drug discoveries: a machine-learning perspective

por Xiao, Huan, Yang, Xin, Zhang, Yihao, Zhang, Zongkang, Zhang, Ge, Zhang, Bao-Ting
Publicado 2023

Electrical Stimulation Influences Satellite Cell Proliferation and Apoptosis in Unloading-Induced Muscle Atrophy in Mice

por Guo, Bao-Sheng, Cheung, Kwok-Kuen, Yeung, Simon S., Zhang, Bao-Ting, Yeung, Ella W.
Publicado 2012

Icaritin Inhibits Collagen Degradation-Related Factors and Facilitates Collagen Accumulation in Atherosclerotic Lesions: A Potential Action for Plaque Stabilization

por Zhang, Zong-Kang, Li, Jie, Yan, De-Xin, Leung, Wing-Nang, Zhang, Bao-Ting
Publicado 2016

Pros and Cons of Denosumab Treatment for Osteoporosis and Implication for RANKL Aptamer Therapy

por Zhang, Ning, Zhang, Zong-Kang, Yu, Yuanyuan, Zhuo, Zhenjian, Zhang, Ge, Zhang, Bao-Ting
Publicado 2020

Artificial Intelligence in Aptamer–Target Binding Prediction

por Chen, Zihao, Hu, Long, Zhang, Bao-Ting, Lu, Aiping, Wang, Yaofeng, Yu, Yuanyuan, Zhang, Ge
Publicado 2021

Icaritin requires Phosphatidylinositol 3 kinase (PI3K)/Akt signaling to counteract skeletal muscle atrophy following mechanical unloading

por ZHANG, Zong-Kang, LI, Jie, LIU, Jin, GUO, Baosheng, LEUNG, Albert, ZHANG, Ge, ZHANG, Bao-Ting
Publicado 2016

Connective Tissue Growth Factor: From Molecular Understandings to Drug Discovery

por Chen, Zihao, Zhang, Ning, Chu, Hang Yin, Yu, Yuanyuan, Zhang, Zong-Kang, Zhang, Ge, Zhang, Bao-Ting
Publicado 2020

Drug Discovery of DKK1 Inhibitors

por Jiang, Hewen, Zhang, Zongkang, Yu, Yuanyuan, Chu, Hang Yin, Yu, Sifan, Yao, Shanshan, Zhang, Ge, Zhang, Bao-Ting
Publicado 2022

A newly identified lncRNA MAR1 acts as a miR‐487b sponge to promote skeletal muscle differentiation and regeneration

por Zhang, Zong‐Kang, Li, Jie, Guan, Daogang, Liang, Chao, Zhuo, Zhenjian, Liu, Jin, Lu, Aiping, Zhang, Ge, Zhang, Bao‐Ting
Publicado 2018

Long Noncoding RNA lncMUMA Reverses Established Skeletal Muscle Atrophy following Mechanical Unloading

por Zhang, Zong-Kang, Li, Jie, Guan, Daogang, Liang, Chao, Zhuo, Zhenjian, Liu, Jin, Lu, Aiping, Zhang, Ge, Zhang, Bao-Ting
Publicado 2018

Structural Biology for the Molecular Insight between Aptamers and Target Proteins

por Zhang, Ning, Chen, Zihao, Liu, Dingdong, Jiang, Hewen, Zhang, Zong-Kang, Lu, Aiping, Zhang, Bao-Ting, Yu, Yuanyuan, Zhang, Ge
Publicado 2021

Dickkopf-1: A Promising Target for Cancer Immunotherapy

por Chu, Hang Yin, Chen, Zihao, Wang, Luyao, Zhang, Zong-Kang, Tan, Xinhuan, Liu, Shuangshuang, Zhang, Bao-Ting, Lu, Aiping, Yu, Yuanyuan, Zhang, Ge
Publicado 2021

The effects of low frequency electrical stimulation on satellite cell activity in rat skeletal muscle during hindlimb suspension

por Zhang, Bao-Ting, Yeung, Simon S, Liu, Yue, Wang, Hong-Hui, Wan, Yu-Min, Ling, Shu-Kuan, Zhang, Hong-Yu, Li, Ying-Hui, Yeung, Ella W
Publicado 2010

Bioinformatics and Microarray Analysis of miRNAs in Aged Female Mice Model Implied New Molecular Mechanisms for Impaired Fracture Healing

por He, Bing, Zhang, Zong-Kang, Liu, Jin, He, Yi-Xin, Tang, Tao, Li, Jie, Guo, Bao-Sheng, Lu, Ai-Ping, Zhang, Bao-Ting, Zhang, Ge
Publicado 2016

A Loop‐Based and AGO‐Incorporated Virtual Screening Model Targeting AGO‐Mediated miRNA–mRNA Interactions for Drug Discovery to Rescue Bone Phenotype in Genetically Modified Mice...

por Zhuo, Zhenjian, Wan, Youyang, Guan, Daogang, Ni, Shuaijian, Wang, Luyao, Zhang, Zongkang, Liu, Jin, Liang, Chao, Yu, Yuanyuan, Lu, Aiping, Zhang, Ge, Zhang, Bao‐Ting
Publicado 2020

TAK1 inhibition attenuates both inflammation and fibrosis in experimental pneumoconiosis

por Li, Jie, Liang, Chao, Zhang, Zong-Kang, Pan, Xiaohua, Peng, Songlin, Lee, Wing-Sze, Lu, Aiping, Lin, Zhixiu, Zhang, Ge, Leung, Wing-Nang, Zhang, Bao-Ting
Publicado 2017

Combination of inflammation-related cytokines promotes long-term muscle stem cell expansion

por Fu, Xin, Xiao, Jun, Wei, Yuning, Li, Sheng, Liu, Yan, Yin, Jie, Sun, Kun, Sun, Hao, Wang, Huating, Zhang, Zongkang, Zhang, Bao-Ting, Sheng, Chun, Wang, Hongyan, Hu, Ping
Publicado 2015

Src inhibitor reduces permeability without disturbing vascularization and prevents bone destruction in steroid-associated osteonecrotic lesions in rabbits

por He, Yi-Xin, Liu, Jin, Guo, Baosheng, Wang, Yi-Xiang, Pan, Xiaohua, Li, Defang, Tang, Tao, Chen, Yang, Peng, Songlin, Bian, Zhaoxiang, Liang, Zicai, Zhang, Bao-Ting, Lu, Aiping, Zhang, Ge
Publicado 2015

Increased PLEKHO1 within osteoblasts suppresses Smad‐dependent BMP signaling to inhibit bone formation during aging

por Liu, Jin, Liang, Chao, Guo, Baosheng, Wu, Xiaohao, Li, Defang, Zhang, Zongkang, Zheng, Kang, Dang, Lei, He, Xiaojuan, Lu, Changwei, Peng, Songlin, Pan, Xiaohua, Zhang, Bao‐Ting, Lu, Aiping, Zhang, Ge
Publicado 2017

Inhibition of osteoblastic Smurf1 promotes bone formation in mouse models of distinctive age-related osteoporosis

por Liang, Chao, Peng, Songlin, Li, Jie, Lu, Jun, Guan, Daogang, Jiang, Feng, Lu, Cheng, Li, Fangfei, He, Xiaojuan, Zhu, Hailong, Au, D. W. T., Yang, Dazhi, Zhang, Bao-Ting, Lu, Aiping, Zhang, Ge
Publicado 2018