Understanding metabolic alterations and heterogeneity in cancer progression through validated immunodetection of key molecular components: a case of carbonic anhydrase IX

por Takacova, Martina, Kajanova, Ivana, Kolarcikova, Maria, Lapinova, Jana, Zatovicova, Miriam, Pastorekova, Silvia
Publicado 2022

Hypoxic marker CA IX and adhesion mediator β-catenin are downregulated by lymphocytic choriomeningitis virus persistent infection

por Fabianova, Andrea, Barathova, Monika, Csaderova, Lucia, Simko, Veronika, Zatovicova, Miriam, Labudova, Martina, Pastorek, Jaromir
Publicado 2018

ADAM10 mediates shedding of carbonic anhydrase IX ectodomain non-redundantly to ADAM17

por Zatovicova, Miriam, Kajanova, Ivana, Takacova, Martina, Jelenska, Lenka, Sedlakova, Olga, Labudova, Martina, Pastorekova, Silvia
Publicado 2022

Carbonic Anhydrase IX in Tumor Tissue and Plasma of Breast Cancer Patients: Reliable Biomarker of Hypoxia and Prognosis

por Rezuchova, Ingeborg, Bartosova, Maria, Belvoncikova, Petra, Takacova, Martina, Zatovicova, Miriam, Jelenska, Lenka, Csaderova, Lucia, Meciarova, Iveta, Pohlodek, Kamil
Publicado 2023

Carnosine inhibits carbonic anhydrase IX-mediated extracellular acidosis and suppresses growth of HeLa tumor xenografts

por Ditte, Zuzana, Ditte, Peter, Labudova, Martina, Simko, Veronika, Iuliano, Filippo, Zatovicova, Miriam, Csaderova, Lucia, Pastorekova, Silvia, Pastorek, Jaromir
Publicado 2014

Apoptosis-induced ectodomain shedding of hypoxia-regulated carbonic anhydrase IX from tumor cells: a double-edged response to chemotherapy

por Vidlickova, Ivana, Dequiedt, Franck, Jelenska, Lenka, Sedlakova, Olga, Pastorek, Michal, Stuchlik, Stanislav, Pastorek, Jaromir, Zatovicova, Miriam, Pastorekova, Silvia
Publicado 2016

Tumor Microenvironmental Changes Induced by the Sulfamate Carbonic Anhydrase IX Inhibitor S4 in a Laryngeal Tumor Model

por Meijer, Tineke W. H., Bussink, Johan, Zatovicova, Miriam, Span, Paul N., Lok, Jasper, Supuran, Claudiu T., Kaanders, Johannes H. A. M.
Publicado 2014

Carbonic Anhydrase IX—Mouse versus Human

por Takacova, Martina, Barathova, Monika, Zatovicova, Miriam, Golias, Tereza, Kajanova, Ivana, Jelenska, Lenka, Sedlakova, Olga, Svastova, Eliska, Kopacek, Juraj, Pastorekova, Silvia
Publicado 2019

PIMT Binding to C-Terminal Ala459 of CAIX Is Involved in Inside-Out Signaling Necessary for Its Catalytic Activity

por Simko, Veronika, Belvoncikova, Petra, Csaderova, Lucia, Labudova, Martina, Grossmannova, Katarina, Zatovicova, Miriam, Kajanova, Ivana, Skultety, Ludovit, Barathova, Monika, Pastorek, Jaromir
Publicado 2020

Novel humanized monoclonal antibodies for targeting hypoxic human tumors via two distinct extracellular domains of carbonic anhydrase IX

por Zatovicova, Miriam, Kajanova, Ivana, Barathova, Monika, Takacova, Martina, Labudova, Martina, Csaderova, Lucia, Jelenska, Lenka, Svastova, Eliska, Pastorekova, Silvia, Harris, Adrian L., Pastorek, Jaromir
Publicado 2022

CAIX Regulates Invadopodia Formation through Both a pH-Dependent Mechanism and Interplay with Actin Regulatory Proteins

por Debreova, Michaela, Csaderova, Lucia, Burikova, Monika, Lukacikova, Lubomira, Kajanova, Ivana, Sedlakova, Olga, Kery, Martin, Kopacek, Juraj, Zatovicova, Miriam, Bizik, Jozef, Pastorekova, Silvia, Svastova, Eliska
Publicado 2019

A Multifunctional Graphene Oxide Platform for Targeting Cancer

por Bugárová, Nikola, Špitálsky, Zdenko, Mičušík, Matej, Bodík, Michal, Šiffalovič, Peter, Koneracká, Martina, Závišová, Vlasta, Kubovčíková, Martina, Kajanová, Ivana, Zaťovičová, Miriam, Pastoreková, Silvia, Šlouf, Miroslav, Majková, Eva, Omastová, Mária
Publicado 2019

Impairment of carbonic anhydrase IX ectodomain cleavage reinforces tumorigenic and metastatic phenotype of cancer cells

por Kajanova, Ivana, Zatovicova, Miriam, Jelenska, Lenka, Sedlakova, Olga, Barathova, Monika, Csaderova, Lucia, Debreova, Michaela, Lukacikova, Lubomira, Grossmannova, Katarina, Labudova, Martina, Golias, Tereza, Svastova, Eliska, Ludwig, Andreas, Muller, Petr, Vojtesek, Borivoj, Pastorek, Jaromir, Pastorekova, Silvia
Publicado 2020

Prognostic value of serum carbonic anhydrase IX in testicular germ cell tumor patients

por Kalavska, Katarina, Chovanec, Michal, Zatovicova, Miriam, Takacova, Martina, Gronesova, Paulina, Svetlovska, Daniela, Baratova, Magdalena, Miskovska, Vera, Obertova, Jana, Palacka, Patrik, Rajec, Jan, Sycova-Mila, Zuzana, Cierna, Zuzana, Kajo, Karol, Spanik, Stanislav, Babal, Pavel, Mardiak, Jozef, Pastorekova, Silvia, Mego, Michal
Publicado 2016