Structure and function of the human Gly1619Arg polymorphism of M6P/IGF2R domain 11 implicated in IGF2 dependent growth

por Rezgui, Dellel, Williams, Christopher, Savage, Sharon A, Prince, Stuart N, Zaccheo, Oliver J, Jones, E Yvonne, Crump, Matthew P, Hassan, A Bassim
Publicado 2009

Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum hal...

por Adams, Ralph, Griffin, Laura, Compson, Joanne E., Jairaj, Mark, Baker, Terry, Ceska, Tom, West, Shauna, Zaccheo, Oliver, Davé, Emma, Lawson, Alastair DG., Humphreys, David P., Heywood, Sam
Publicado 2016

Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding

por Davé, Emma, Adams, Ralph, Zaccheo, Oliver, Carrington, Bruce, Compson, Joanne E., Dugdale, Sarah, Airey, Michael, Malcolm, Sarah, Hailu, Hanna, Wild, Gavin, Turner, Alison, Heads, James, Sarkar, Kaushik, Ventom, Andrew, Marshall, Diane, Jairaj, Mark, Kopotsha, Tim, Christodoulou, Louis, Zamacona, Miren, Lawson, Alastair D., Heywood, Sam, Humphreys, David P.
Publicado 2016

Engineered hexavalent Fc proteins with enhanced Fc-gamma receptor avidity provide insights into immune-complex interactions

por Rowley, Tania F., Peters, Shirley J., Aylott, Mike, Griffin, Robert, Davies, Nicola L., Healy, Louise J., Cutler, Rona M., Eddleston, Alison, Pither, Thomas L., Sopp, Joshua M., Zaccheo, Oliver, Fossati, Gianluca, Cain, Katharine, Ventom, Andrew M., Hailu, Hanna, Ward, Eleanor J., Sherington, John, Brennan, Frank R., Fallah-Arani, Farnaz, Humphreys, David P.
Publicado 2018

Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362

por Lowe, Martin A., Cardenas, Alvaro, Valentin, Jean-Pierre, Zhu, Zhaoning, Abendroth, Jan, Castro, Jose L., Class, Reiner, Delaunois, Annie, Fleurance, Renaud, Gerets, Helga, Gryshkova, Vitalina, King, Lloyd, Lorimer, Donald D., MacCoss, Malcolm, Rowley, Julian H., Rosseels, Marie-Luce, Royer, Leandro, Taylor, Richard D., Wong, Melanie, Zaccheo, Oliver, Chavan, Vishal P., Ghule, Gokul A., Tapkir, Bapusaheb K., Burrows, Jeremy N., Duffey, Maëlle, Rottmann, Matthias, Wittlin, Sergio, Angulo-Barturen, Iñigo, Jiménez-Díaz, María Belén, Striepen, Josefine, Fairhurst, Kate J., Yeo, Tomas, Fidock, David A., Cowman, Alan F., Favuzza, Paola, Crespo-Fernandez, Benigno, Gamo, Francisco Javier, Goldberg, Daniel E., Soldati-Favre, Dominique, Laleu, Benoît, de Haro, Teresa
Publicado 2022