Using Enteroendocrine Cell–Enriched Human Enteroids to Evaluate Responses to Gut Stimuli

por Zachos, Nicholas C.
Publicado 2019

Editorial: Host-Microbiome Interactions and Influence on Performance During Acute Environmental, Nutritional, Physical, and Cognitive Stress, Volume II

por Pearce, Sarah C., Karl, J. Philip, Zachos, Nicholas C.
Publicado 2022

Carbachol-Mediated Endocytosis of NHE3 Involves a Clathrin-Independent Mechanism Requiring Lipid Rafts and Cdc42

por Zachos, Nicholas C., Alamelumangpuram, Bharath, Lee, Luke J., Wang, Peng, Kovbasnjuk, Olga
Publicado 2014

Regenerative Intestinal Stem Cells Induced by Acute and Chronic Injury: The Saving Grace of the Epithelium?

por Rees, William D., Tandun, Rene, Yau, Enoch, Zachos, Nicholas C., Steiner, Theodore S.
Publicado 2020

Epithelial and Neutrophil Interactions and Coordinated Response to Shigella in a Human Intestinal Enteroid-Neutrophil Coculture Model

por Lemme-Dumit, Jose M., Doucet, Michele, Zachos, Nicholas C., Pasetti, Marcela F.
Publicado 2022

Protocol for measuring transcytosis and recycling of IgG in intestinal epithelial Caco-2 cells and primary human intestinal organoids

por Maeda, Keiko, Gwilt, Katlynn Bugda, Schmieder, Stefanie S., Zachos, Nicholas C., Lencer, Wayne I.
Publicado 2023

Recovery of Infectious Human Norovirus GII.4 Sydney From Fomites via Replication in Human Intestinal Enteroids

por Overbey, Katie N., Zachos, Nicholas C., Coulter, Caroline, Jacangelo, Joseph, Schwab, Kellogg J.
Publicado 2021

Enterotoxigenic Escherichia coli is phagocytosed by macrophages underlying villus-like intestinal epithelial cells: modeling ex vivo innate immune defenses of the human gut

por Noel, Gaelle, Doucet, Michele, Nataro, James P., Kaper, James B., Zachos, Nicholas C., Pasetti, Marcela F.
Publicado 2018

Evaluating Shigella flexneri Pathogenesis in the Human Enteroid Model

por Ranganathan, Sridevi, Doucet, Michele, Grassel, Christen L., Delaine-Elias, BreOnna, Zachos, Nicholas C., Barry, Eileen M.
Publicado 2019

A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions

por Noel, Gaelle, Baetz, Nicholas W., Staab, Janet F., Donowitz, Mark, Kovbasnjuk, Olga, Pasetti, Marcela F., Zachos, Nicholas C.
Publicado 2017

Erratum: A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions

por Noel, Gaelle, Baetz, Nicholas W., Staab, Janet F., Donowitz, Mark, Kovbasnjuk, Olga, Pasetti, Marcela F., Zachos, Nicholas C.
Publicado 2017

Intestinal in vitro and ex vivo Models to Study Host-Microbiome Interactions and Acute Stressors

por Pearce, Sarah C., Coia, Heidi G., Karl, J. P., Pantoja-Feliciano, Ida G., Zachos, Nicholas C., Racicot, Kenneth
Publicado 2018

Yersinia pseudotuberculosis YopE prevents uptake by M cells and instigates M cell extrusion in human ileal enteroid-derived monolayers

por Fasciano, Alyssa C., Dasanayake, Gaya S., Estes, Mary K., Zachos, Nicholas C., Breault, David T., Isberg, Ralph R., Tan, Shumin, Mecsas, Joan
Publicado 2021

Chronic Inflammation in Ulcerative Colitis Causes Long-Term Changes in Goblet Cell Function

por Singh, Varsha, Johnson, Kelli, Yin, Jianyi, Lee, Sun, Lin, Ruxian, Yu, Huimin, In, Julie, Foulke-Abel, Jennifer, Zachos, Nicholas C., Donowitz, Mark, Rong, Yan
Publicado 2021

Mucus layer modeling of human colonoids during infection with enteroaggragative E. coli

por Liu, Lixia, Saitz-Rojas, Waleska, Smith, Rachel, Gonyar, Laura, In, Julie G., Kovbasnjuk, Olga, Zachos, Nicholas C., Donowitz, Mark, Nataro, James P., Ruiz-Perez, Fernando
Publicado 2020

Enterohemorrhagic Escherichia coli Reduces Mucus and Intermicrovillar Bridges in Human Stem Cell-Derived Colonoids

por In, Julie, Foulke-Abel, Jennifer, Zachos, Nicholas C., Hansen, Anne-Marie, Kaper, James B., Bernstein, Harris D., Halushka, Marc, Blutt, Sarah, Estes, Mary K., Donowitz, Mark, Kovbasnjuk, Olga
Publicado 2015

Epithelial WNT2B and Desert Hedgehog Are Necessary for Human Colonoid Regeneration after Bacterial Cytotoxin Injury

por In, Julie G., Yin, Jianyi, Atanga, Roger, Doucet, Michele, Cole, Robert N., DeVine, Lauren, Donowitz, Mark, Zachos, Nicholas C., Blutt, Sarah E., Estes, Mary K., Kovbasnjuk, Olga
Publicado 2020

Epac1 mediates protein kinase A–independent mechanism of forskolin-activated intestinal chloride secretion

por Hoque, Kazi Mirajul, Woodward, Owen M., van Rossum, Damian B., Zachos, Nicholas C., Chen, Linxi, Leung, George P.H., Guggino, William B., Guggino, Sandra E., Tse, Chung-Ming
Publicado 2010

Enterohemorrhagic E. coli (EHEC)—Secreted Serine Protease EspP Stimulates Electrogenic Ion Transport in Human Colonoid Monolayers

por Tse, C. Ming, In, Julie G., Yin, Jianyi, Donowitz, Mark, Doucet, Michele, Foulke-Abel, Jennifer, Ruiz-Perez, Fernando, Nataro, James P., Zachos, Nicholas C., Kaper, James B., Kovbasnjuk, Olga
Publicado 2018

Intestinal stem cell-derived enteroids from morbidly obese patients preserve obesity-related phenotypes: Elevated glucose absorption and gluconeogenesis

por Hasan, Nesrin M., Johnson, Kelli F., Yin, Jianyi, Baetz, Nicholas W., Fayad, Lea, Sherman, Vadim, Blutt, Sarah E., Estes, Mary K., Kumbhari, Vivek, Zachos, Nicholas C., Kovbasnjuk, Olga
Publicado 2020