Sequential use of Ad26-based vaccine regimens in NHP to induce immunity against different disease targets

por Khan, Selina, Salisch, Nadine C., Gil, Ana Izquierdo, Boedhoe, Satish, Boer, Karin Feddes-de, Serroyen, Jan, Schuitemaker, Hanneke, Zahn, Roland C.
Publicado 2022

Restrained expansion of the recall germinal center response as biomarker of protection for influenza vaccination in mice

por Kil, Laurens P., Vaneman, Joost, van der Lubbe, Joan E. M., Czapska-Casey, Dominika, Tolboom, Jeroen T. B. M., Roozendaal, Ramon, Zahn, Roland C., Kuipers, Harmjan, Solforosi, Laura
Publicado 2019

Inhibition of Adaptive Immune Responses Leads to a Fatal Clinical Outcome in SIV-Infected Pigtailed Macaques but Not Vervet African Green Monkeys

por Schmitz, Jörn E., Zahn, Roland C., Brown, Charles R., Rett, Melisa D., Li, Ming, Tang, Haili, Pryputniewicz, Sarah, Byrum, Russell A., Kaur, Amitinder, Montefiori, David C., Allan, Jonathan S., Goldstein, Simoy, Hirsch, Vanessa M.
Publicado 2009

Durability and expansion of neutralizing antibody breadth following Ad26.COV2.S vaccination of mice

por Mahrokhian, Shant H., Tostanoski, Lisa H., Jacob-Dolan, Catherine, Zahn, Roland C., Wegmann, Frank, McMahan, Katherine, Yu, Jingyou, Gebre, Makda S., Bondzie, Esther A., Wan, Huahua, Powers, Olivia, Ye, Tianyi, Barrett, Julia, Schuitemaker, Hanneke, Barouch, Dan H.
Publicado 2022

Mini-HA Is Superior to Full Length Hemagglutinin Immunization in Inducing Stem-Specific Antibodies and Protection Against Group 1 Influenza Virus Challenges in Mice

por van der Lubbe, Joan E. M., Verspuij, Johan W. A., Huizingh, Jeroen, Schmit-Tillemans, Sonja P. R., Tolboom, Jeroen T. B. M., Dekking, Liesbeth E. H. A., Kwaks, Ted, Brandenburg, Börries, Meijberg, Wim, Zahn, Roland C., Roozendaal, Ramon, Kuipers, Harmjan
Publicado 2018

Combination Ad26.RSV.preF/preF protein vaccine induces superior protective immunity compared with individual vaccine components in preclinical models

por Saeland, Eirikur, van der Fits, Leslie, Bolder, Renske, Heemskerk-van der Meer, Marjolein, Drijver, Joke, van Polanen, Yolinda, Vaneman, Cornelis, Tettero, Lisanne, Cox, Freek, Serroyen, Jan, Jorgensen, Matthew J., Langedijk, Johannes P. M., Schuitemaker, Hanneke, Callendret, Benoit, Zahn, Roland C.
Publicado 2023

Mini-hemagglutinin vaccination induces cross-reactive antibodies in pre-exposed NHP that protect mice against lethal influenza challenge

por van der Lubbe, Joan E. M., Huizingh, Jeroen, Verspuij, Johan W. A., Tettero, Lisanne, Schmit-Tillemans, Sonja P. R., Mooij, Petra, Mortier, Daniella, Koopman, Gerrit, Bogers, Willy M. J. M., Dekking, Liesbeth, Meijberg, Wim, Kwaks, Ted, Brandenburg, Boerries, Tolboom, Jeroen T. B. M., Schuitemaker, Hanneke, Roozendaal, Ramon, Kuipers, Harmjan, Zahn, Roland C.
Publicado 2018

Booster with Ad26.COV2.S or Omicron-adapted vaccine enhanced immunity and efficacy against SARS-CoV-2 Omicron in macaques

por Solforosi, Laura, Costes, Lea M. M., Tolboom, Jeroen T. B. M., McMahan, Katherine, Anioke, Tochi, Hope, David, Murdza, Tetyana, Sciacca, Michaela, Bouffard, Emily, Barrett, Julia, Wu, Cindy, Hachmann, Nicole, Miller, Jessica, Yu, Jingyou, He, Xuan, Jacob-Dolan, Catherine, Huber, Sietske K. Rosendahl, Dekking, Liesbeth, Chamanza, Ronnie, Choi, Ying, Boer, Karin Feddes-de, Barouch, Dan H., Schuitemaker, Hanneke, Zahn, Roland C., Wegmann, Frank
Publicado 2023

Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

por Bos, Rinke, Rutten, Lucy, van der Lubbe, Joan E. M., Bakkers, Mark J. G., Hardenberg, Gijs, Wegmann, Frank, Zuijdgeest, David, de Wilde, Adriaan H., Koornneef, Annemart, Verwilligen, Annemiek, van Manen, Danielle, Kwaks, Ted, Vogels, Ronald, Dalebout, Tim J., Myeni, Sebenzile K., Kikkert, Marjolein, Snijder, Eric J., Li, Zhenfeng, Barouch, Dan H., Vellinga, Jort, Langedijk, Johannes P. M., Zahn, Roland C., Custers, Jerome, Schuitemaker, Hanneke
Publicado 2020

Ad26.COV2.S protects Syrian hamsters against G614 spike variant SARS-CoV-2 and does not enhance respiratory disease

por van der Lubbe, Joan E. M., Rosendahl Huber, Sietske K., Vijayan, Aneesh, Dekking, Liesbeth, van Huizen, Ella, Vreugdenhil, Jessica, Choi, Ying, Baert, Miranda R. M., Feddes-de Boer, Karin, Izquierdo Gil, Ana, van Heerden, Marjolein, Dalebout, Tim J., Myeni, Sebenzile K., Kikkert, Marjolein, Snijder, Eric J., de Waal, Leon, Stittelaar, Koert J., Tolboom, Jeroen T. B. M., Serroyen, Jan, Muchene, Leacky, van der Fits, Leslie, Rutten, Lucy, Langedijk, Johannes P. M., Barouch, Dan H., Schuitemaker, Hanneke, Zahn, Roland C., Wegmann, Frank
Publicado 2021

Passive transfer of Ad26.COV2.S-elicited IgG from humans attenuates SARS-CoV-2 disease in hamsters

por Tostanoski, Lisa H., Chandrashekar, Abishek, Patel, Shivani, Yu, Jingyou, Jacob-Dolan, Catherine, Chang, Aiquan, Powers, Olivia C., Sellers, Daniel, Gardner, Sarah, Barrett, Julia, Sanborn, Owen, Stephenson, Kathryn E., Ansel, Jessica L., Jaegle, Kate, Seaman, Michael S., Porto, Maciel, Lok, Megan, Spence, Brittany, Cayer, Kathleen, Nase, Danielle, Holman, Shaikim, Bradette, Heath, Kar, Swagata, Andersen, Hanne, Lewis, Mark G., Cox, Freek, Tolboom, Jeroen T. B. M., de Groot, Anne Marit, Heerwegh, Dirk, Le Gars, Mathieu, Sadoff, Jerald, Wegmann, Frank, Zahn, Roland C., Schuitemaker, Hanneke, Barouch, Dan H.
Publicado 2022

Immunogenicity and efficacy of one and two doses of Ad26.COV2.S COVID vaccine in adult and aged NHP

por Solforosi, Laura, Kuipers, Harmjan, Jongeneelen, Mandy, Rosendahl Huber, Sietske K., van der Lubbe, Joan E.M., Dekking, Liesbeth, Czapska-Casey, Dominika N., Izquierdo Gil, Ana, Baert, Miranda R.M., Drijver, Joke, Vaneman, Joost, van Huizen, Ella, Choi, Ying, Vreugdenhil, Jessica, Kroos, Sanne, de Wilde, Adriaan H., Kourkouta, Eleni, Custers, Jerome, van der Vlugt, Remko, Veldman, Daniel, Huizingh, Jeroen, Kaszas, Krisztian, Dalebout, Tim J., Myeni, Sebenzile K., Kikkert, Marjolein, Snijder, Eric J., Barouch, Dan H., Böszörményi, Kinga P., Stammes, Marieke A., Kondova, Ivanela, Verschoor, Ernst J., Verstrepen, Babs E., Koopman, Gerrit, Mooij, Petra, Bogers, Willy M.J.M., van Heerden, Marjolein, Muchene, Leacky, Tolboom, Jeroen T.B.M., Roozendaal, Ramon, Brandenburg, Boerries, Schuitemaker, Hanneke, Wegmann, Frank, Zahn, Roland C.
Publicado 2021