Messenger RNA vaccines for cancer immunotherapy: progress promotes promise

por Huff, Amanda L., Jaffee, Elizabeth M., Zaidi, Neeha
Publicado 2022

Targeting of the non-mutated tumor antigen HER2/neu to mature dendritic cells induces an integrated immune response that protects against breast cancer in mice

por Wang, Bei, Zaidi, Neeha, He, Li-Zhen, Zhang, Li, Kuroiwa, Janelle MY, Keler, Tibor, Steinman, Ralph M
Publicado 2012

Role of in silico structural modeling in predicting immunogenic neoepitopes for cancer vaccine development

por Zaidi, Neeha, Soban, Mariya, Chen, Fangluo, Kinkead, Heather, Mathew, Jocelyn, Yarchoan, Mark, Armstrong, Todd D., Haider, Shozeb, Jaffee, Elizabeth M.
Publicado 2020

Transfer learning between preclinical models and human tumors identifies a conserved NK cell activation signature in anti-CTLA-4 responsive tumors

por Davis-Marcisak, Emily F., Fitzgerald, Allison A., Kessler, Michael D., Danilova, Ludmila, Jaffee, Elizabeth M., Zaidi, Neeha, Weiner, Louis M., Fertig, Elana J.
Publicado 2021

A Random Forest Genomic Classifier for Tumor Agnostic Prediction of Response to Anti-PD1 Immunotherapy

por Bigelow, Emma, Saria, Suchi, Piening, Brian, Curti, Brendan, Dowdell, Alexa, Weerasinghe, Roshanthi, Bifulco, Carlo, Urba, Walter, Finkelstein, Noam, Fertig, Elana J, Baras, Alex, Zaidi, Neeha, Jaffee, Elizabeth, Yarchoan, Mark
Publicado 2022

Barcoding intracellular reverse transcription enables high-throughput phenotype-coupled T cell receptor analyses

por Jayaraman, Sahana, Montagne, Janelle M., Nirschl, Thomas R., Marcisak, Emily, Johnson, Jeanette, Huff, Amanda, Hsiao, Meng-Hsuan, Nauroth, Julie, Heumann, Thatcher, Zarif, Jelani C., Jaffee, Elizabeth M., Azad, Nilo, Fertig, Elana J., Zaidi, Neeha, Larman, H. Benjamin
Publicado 2023

Cancer vaccines

por Schiller, John T., Lowy, Douglas R., Frazer, Ian H., Finn, Olivera J., Vilar, Eduardo, Lyerly, H. Kim, Gnjatic, Sacha, Zaidi, Neeha, Ott, Patrick A., Balachandran, Vinod P., Dietrich, Pierre-Yves, Migliorini, Denis, Vonderheide, Robert H., Domchek, Susan M.
Publicado 2022

Multi-omic profiling of lung and liver tumor microenvironments of metastatic pancreatic cancer reveals site-specific immune regulatory pathways

por Ho, Won Jin, Erbe, Rossin, Danilova, Ludmila, Phyo, Zaw, Bigelow, Emma, Stein-O’Brien, Genevieve, Thomas, Dwayne L., Charmsaz, Soren, Gross, Nicole, Woolman, Skylar, Cruz, Kayla, Munday, Rebecca M., Zaidi, Neeha, Armstrong, Todd D., Sztein, Marcelo B., Yarchoan, Mark, Thompson, Elizabeth D., Jaffee, Elizabeth M., Fertig, Elana J.
Publicado 2021

Evaluating the impact of age on immune checkpoint therapy biomarkers

por Erbe, Rossin, Wang, Zheyu, Wu, Sharon, Xiu, Joanne, Zaidi, Neeha, La, Jennifer, Tuck, David, Fillmore, Nathanael, Giraldo, Nicolas A., Topper, Michael, Baylin, Stephen, Lippman, Marc, Isaacs, Claudine, Basho, Reva, Serebriiskii, Ilya, Lenz, Heinz-Josef, Astsaturov, Igor, Marshall, John, Taverna, Josephine, Lee, Jerry, Jaffee, Elizabeth M., Torres, Evanthia T. Roussos, Weeraratna, Ashani, Easwaran, Hariharan, Fertig, Elana J.
Publicado 2021

A Statin-Loaded Reconstituted High-Density Lipoprotein Nanoparticle Inhibits Atherosclerotic Plaque Inflammation

por Duivenvoorden, Raphaël, Tang, Jun, Cormode, David P., Mieszawska, Aneta J., Izquierdo-Garcia, David, Ozcan, Canturk, Otten, Maarten J., Zaidi, Neeha, Lobatto, Mark E., van Rijs, Sarian M., Priem, Bram, Kuan, Emma L., Martel, Catherine, Hewing, Bernd, Sager, Hendrik, Nahrendorf, Matthias, Randolph, Gwendalyn J., Stroes, Erik S.G., Fuster, Valentin, Fisher, Edward A., Fayad, Zahi A., Mulder, Willem J.M.
Publicado 2014

Implantation of a neoantigen-targeted hydrogel vaccine prevents recurrence of pancreatic adenocarcinoma after incomplete resection

por Delitto, Daniel, Zabransky, Daniel J., Chen, Fangluo, Thompson, Elizabeth D., Zimmerman, Jacquelyn W., Armstrong, Todd D., Leatherman, James M., Suri, Reecha, Lopez-Vidal, Tamara Y., Huff, Amanda L., Lyman, Melissa R., Guinn, Samantha R., Baretti, Marina, Kagohara, Luciane T., Ho, Won Jin, Azad, Nilofer S., Burns, William R., He, Jin, Wolfgang, Christopher L., Burkhart, Richard A., Zheng, Lei, Yarchoan, Mark, Zaidi, Neeha, Jaffee, Elizabeth M.
Publicado 2021

Peptide-TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T cell immunity to tumor antigens

por Lynn, Geoffrey M., Sedlik, Christine, Baharom, Faezzah, Zhu, Yaling, Ramirez-Valdez, Ramiro A., Coble, Vincent L., Tobin, Kennedy, Nichols, Sarah R., Itzkowitz, Yaakov, Zaidi, Neeha, Gammon, Joshua M., Blobel, Nicolas J., Denizeau, Jordan, de la Rochere, Philippe, Francica, Brian J., Decker, Brennan, Maciejewski, Mateusz, Cheung, Justin, Yamane, Hidehiro, Smelkinson, Margery G., Francica, Joseph R., Laga, Richard, Bernstock, Joshua D., Seymour, Leonard W., Drake, Charles G., Jewell, Christopher M., Lantz, Olivier, Piaggio, Eliane, Ishizuka, Andrew S., Seder, Robert A.
Publicado 2020

Digitize your Biology! Modeling multicellular systems through interpretable cell behavior

por Johnson, Jeanette A.I., Stein-O’Brien, Genevieve L., Booth, Max, Heiland, Randy, Kurtoglu, Furkan, Bergman, Daniel R., Bucher, Elmar, Deshpande, Atul, Forjaz, André, Getz, Michael, Godet, Ines, Lyman, Melissa, Metzcar, John, Mitchell, Jacob, Raddatz, Andrew, Rocha, Heber, Solorzano, Jacobo, Sundus, Aneequa, Wang, Yafei, Gilkes, Danielle, Kagohara, Luciane T., Kiemen, Ashley L., Thompson, Elizabeth D., Wirtz, Denis, Wu, Pei-Hsun, Zaidi, Neeha, Zheng, Lei, Zimmerman, Jacquelyn W., Jaffee, Elizabeth M., Hwan Chang, Young, Coussens, Lisa M., Gray, Joe W., Heiser, Laura M., Fertig, Elana J., Macklin, Paul
Publicado 2023

Immune landscape of tertiary lymphoid structures in hepatocellular carcinoma (HCC) treated with neoadjuvant immune checkpoint blockade

por Shu, Daniel H., Ho, Won Jin, Kagohara, Luciane T., Girgis, Alexander, Shin, Sarah M., Danilova, Ludmila, Lee, Jae W., Sidiropoulos, Dimitrios N., Mitchell, Sarah, Munjal, Kabeer, Howe, Kathryn, Bendinelli, Kayla J., Qi, Hanfei, Mo, Guanglan, Montagne, Janelle, Leatherman, James M., Lopez-Vidal, Tamara Y., Zhu, Qingfeng, Huff, Amanda L., Yuan, Xuan, Hernandez, Alexei, Coyne, Erin M., Zaidi, Neeha, Zabransky, Daniel J., Engle, Logan L., Ogurtsova, Aleksandra, Baretti, Marina, Laheru, Daniel, Durham, Jennifer N., Wang, Hao, Anders, Robert, Jaffee, Elizabeth M., Fertig, Elana J., Yarchoan, Mark
Publicado 2023

FSH-blocking therapeutic for osteoporosis

por Gera, Sakshi, Kuo, Tan-Chun, Gumerova, Anisa Azatovna, Korkmaz, Funda, Sant, Damini, DeMambro, Victoria, Sudha, Karthyayani, Padilla, Ashley, Prevot, Geoffrey, Munitz, Jazz, Teunissen, Abraham, van Leent, Mandy MT, Post, Tomas GJM, Fernandes, Jessica C, Netto, Jessica, Sultana, Farhath, Shelly, Eleanor, Rojekar, Satish, Kumar, Pushkar, Cullen, Liam, Chatterjee, Jiya, Pallapati, Anusha, Miyashita, Sari, Kannangara, Hasni, Bhongade, Megha, Sengupta, Puja, Ievleva, Kseniia, Muradova, Valeriia, Batista, Rogerio, Robinson, Cemre, Macdonald, Anne, Hutchison, Susan, Saxena, Mansi, Meseck, Marcia, Caminis, John, Iqbal, Jameel, New, Maria I, Ryu, Vitaly, Kim, Se-Min, Cao, Jay J, Zaidi, Neeha, Fayad, Zahi A, Lizneva, Daria, Rosen, Clifford J, Yuen, Tony, Zaidi, Mone
Publicado 2022