2018 Nobel Prize in medicine awarded to cancer immunotherapy: Immune checkpoint blockade – A personal account

por Zang, Xingxing
Publicado 2018

Protocol for evaluating antitumor activity of KIR3DL3 blockade in an NK cell-based xenogeneic lung tumor model

por Ren, Xiaoxin, Corrigan, Devin T., Zang, Xingxing
Publicado 2022

The PD-1/PD-L1 (B7-H1) Pathway in Chronic Infection-Induced Cytotoxic T Lymphocyte Exhaustion

por Hofmeyer, Kimberly A., Jeon, Hyungjun, Zang, Xingxing
Publicado 2011

Crosstalk between the B7/CD28 and EGFR pathways: Mechanisms and therapeutic opportunities

por Ren, Xiaoxin, Li, Yixian, Nishimura, Christopher, Zang, Xingxing
Publicado 2021

Fibronectin Regulation of Integrin B1 and SLUG in Circulating Tumor Cells

por Huaman, Jeannette, Naidoo, Michelle, Zang, Xingxing, Ogunwobi, Olorunseun O.
Publicado 2019

Tissue-specific expression of B7x protects from CD4 T cell–mediated autoimmunity

por Wei, Joyce, Loke, P’ng, Zang, Xingxing, Allison, James P.
Publicado 2011

B7x and myeloid-derived suppressor cells in the tumor microenvironment: A tale of two cities

por Jeon, Hyungjun, Ohaegbulam, Kim C, Abadi, Yael M, Zang, Xingxing
Publicado 2013

Tumor-expressed immune checkpoint B7x promotes cancer progression and antigen-specific CD8 T cell exhaustion and suppressive innate immune cells

por Ohaegbulam, Kim C., Liu, Weifeng, Jeon, Hyungjun, Almo, Steven C., Zang, Xingxing
Publicado 2017

Immune checkpoint blockade and CAR-T cell therapy in hematologic malignancies

por Wang, Hao, Kaur, Gurbakhash, Sankin, Alexander I., Chen, Fuxiang, Guan, Fangxia, Zang, Xingxing
Publicado 2019

MEDB-76. Evaluating the B7-H3 checkpoint in Medulloblastoma

por Moziak, Kirsten, Picarda, Elodie, Perez, Natalia Muñoz, Galbo, Phillip, Zheng, Deyou, Zang, Xingxing, Martin, Allison
Publicado 2022

Checkpoint regulator B7x is epigenetically regulated by HDAC3 and mediates resistance to HDAC inhibitors by reprogramming the tumor immune environment in colorectal cancer

por Li, Yuxin, Liu, Yao, Zhao, Na, Yang, Xiaojun, Li, Yaqing, Zhai, Fangzheng, Zang, Xingxing, Cui, Wei
Publicado 2020

Immune Checkpoint B7x (B7-H4/B7S1/VTCN1) is Over Expressed in Spontaneous Canine Bladder Cancer: The First Report and its Implications in a Preclinical Model

por Chand, Damini, Dhawan, Deepika, Sankin, Alexander, Ren, Xiaoxin, Lin, Juan, Schoenberg, Mark, Knapp, Deborah W., Zang, Xingxing
Publicado 2019

The immune checkpoint B7x expands tumor-infiltrating Tregs and promotes resistance to anti-CTLA-4 therapy

por John, Peter, Pulanco, Marc C., Galbo, Phillip M., Wei, Yao, Ohaegbulam, Kim C., Zheng, Deyou, Zang, Xingxing
Publicado 2022

The appropriate frequency and function of decidual Tim-3(+)CTLA-4(+)CD8(+) T cells are important in maintaining normal pregnancy

por Wang, Songcun, Sun, Fengrun, Li, Mengdie, Qian, Jinfeng, Chen, Chunqin, Wang, Mingyan, Zang, Xingxing, Li, Dajin, Yu, Min, Du, Meirong
Publicado 2019

Over-Expression and Prognostic Significance of HHLA2, a New Immune Checkpoint Molecule, in Human Clear Cell Renal Cell Carcinoma

por Zhang, Zhen, Liu, Jinyan, Zhang, Chaoqi, Li, Feng, Li, Lifeng, Wang, Dan, Chand, Damini, Guan, Fangxia, Zang, Xingxing, Zhang, Yi
Publicado 2020

Curcumin improves the therapeutic efficacy of Listeria(at)-Mage-b vaccine in correlation with improved T-cell responses in blood of a triple-negative breast cancer model 4T1

por Singh, Manisha, Ramos, Ilyssa, Asafu-Adjei, Denise, Quispe-Tintaya, Wilber, Chandra, Dinesh, Jahangir, Arthee, Zang, Xingxing, Aggarwal, Bharat B, Gravekamp, Claudia
Publicado 2013

The immune checkpoint B7-H3 (CD276) regulates adipocyte progenitor metabolism and obesity development

por Picarda, Elodie, Galbo, Phillip M., Zong, Haihong, Rajan, Meenu Rohini, Wallenius, Ville, Zheng, Deyou, Börgeson, Emma, Singh, Rajat, Pessin, Jeffrey, Zang, Xingxing
Publicado 2022

Heterogeneous Expression of PD-L1, B7x, B7-H3, and HHLA2 in Pulmonary Sarcomatoid Carcinoma and the Related Regulatory Signaling Pathways

por Wang, Feng, Cali Daylan, Ayse Ece, Deng, Lei, Yang, Jihua, Sharma, Janaki, Su, Christopher, Li, Shenduo, Zang, Xingxing, Halmos, Balazs, Borczuk, Alain, Cheng, Haiying
Publicado 2023

Blockade of CTLA-4 and Tim-3 pathways induces fetal loss with altered cytokine profiles by decidual CD4(+)T cells

por Wang, Songcun, Chen, Chunqin, Li, Mengdie, Qian, Jinfeng, Sun, Fengyun, Li, Yunyun, Yu, Min, Wang, Mingyan, Zang, Xingxing, Zhu, Rui, Li, Dajin, Du, Meirong
Publicado 2019

Potentiating effect of reovirus on immune checkpoint inhibition in microsatellite stable colorectal cancer

por Augustine, Titto, John, Peter, Friedman, Tyler, Jiffry, Jeeshan, Guzik, Hillary, Mannan, Rifat, Gupta, Riya, Delano, Catherine, Mariadason, John M., Zang, Xingxing, Maitra, Radhashree, Goel, Sanjay
Publicado 2022