Designing optimal cell factories: integer programming couples elementary mode analysis with regulation

por Jungreuthmayer, Christian, Zanghellini, Jürgen
Publicado 2012

EFMlrs: a Python package for elementary flux mode enumeration via lexicographic reverse search

por Buchner, Bianca A, Zanghellini, Jürgen
Publicado 2021

Optimal knockout strategies in genome-scale metabolic networks using particle swarm optimization

por Nair, Govind, Jungreuthmayer, Christian, Zanghellini, Jürgen
Publicado 2017

Elementary vectors and autocatalytic sets for resource allocation in next-generation models of cellular growth

por Müller, Stefan, Széliová, Diana, Zanghellini, Jürgen
Publicado 2022

Design of Optimally Constructed Metabolic Networks of Minimal Functionality

por Ruckerbauer, David E., Jungreuthmayer, Christian, Zanghellini, Jürgen
Publicado 2014

Comparison and improvement of algorithms for computing minimal cut sets

por Jungreuthmayer, Christian, Nair, Govind, Klamt, Steffen, Zanghellini, Jürgen
Publicado 2013

Designing minimal microbial strains of desired functionality using a genetic algorithm

por Nair, Govind, Jungreuthmayer, Christian, Hanscho, Michael, Zanghellini, Jürgen
Publicado 2015

A mathematical framework for yield (vs. rate) optimization in constraint-based modeling and applications in metabolic engineering

por Klamt, Steffen, Müller, Stefan, Regensburger, Georg, Zanghellini, Jürgen
Publicado 2018

Exact quantification of cellular robustness in genome-scale metabolic networks

por Gerstl, Matthias P., Klamt, Steffen, Jungreuthmayer, Christian, Zanghellini, Jürgen
Publicado 2016

Which sets of elementary flux modes form thermodynamically feasible flux distributions?

por Gerstl, Matthias P., Jungreuthmayer, Christian, Müller, Stefan, Zanghellini, Jürgen
Publicado 2016

Flux tope analysis: studying the coordination of reaction directions in metabolic networks

por Gerstl, Matthias P, Müller, Stefan, Regensburger, Georg, Zanghellini, Jürgen
Publicado 2019

Environmental flexibility does not explain metabolic robustness

por Libiseller-Egger, Julian, Coltman, Ben, Gerstl, Matthias P., Zanghellini, Jürgen
Publicado 2020

Probabilistic quotient’s work and pharmacokinetics’ contribution: countering size effect in metabolic time series measurements

por Gotsmy, Mathias, Brunmair, Julia, Büschl, Christoph, Gerner, Christopher, Zanghellini, Jürgen
Publicado 2022

ecmtool: fast and memory-efficient enumeration of elementary conversion modes

por Buchner, Bianca, Clement, Tom J, de Groot, Daan H, Zanghellini, Jürgen
Publicado 2023

Metabolomics integrated elementary flux mode analysis in large metabolic networks

por Gerstl, Matthias P., Ruckerbauer, David E., Mattanovich, Diethard, Jungreuthmayer, Christian, Zanghellini, Jürgen
Publicado 2015

Avoiding the Enumeration of Infeasible Elementary Flux Modes by Including Transcriptional Regulatory Rules in the Enumeration Process Saves Computational Costs

por Jungreuthmayer, Christian, Ruckerbauer, David E., Gerstl, Matthias P., Hanscho, Michael, Zanghellini, Jürgen
Publicado 2015

CHOmine: an integrated data warehouse for CHO systems biology and modeling

por Gerstl, Matthias P., Hanscho, Michael, Ruckerbauer, David E., Zanghellini, Jürgen, Borth, Nicole
Publicado 2017

Sulfate limitation increases specific plasmid DNA yield and productivity in E. coli fed-batch processes

por Gotsmy, Mathias, Strobl, Florian, Weiß, Florian, Gruber, Petra, Kraus, Barbara, Mairhofer, Juergen, Zanghellini, Jürgen
Publicado 2023

What can mathematical modelling say about CHO metabolism and protein glycosylation?

por Galleguillos, Sarah N., Ruckerbauer, David, Gerstl, Matthias P., Borth, Nicole, Hanscho, Michael, Zanghellini, Jürgen
Publicado 2017

The secretome of Pichia pastoris in fed‐batch cultivations is largely independent of the carbon source but changes quantitatively over cultivation time

por Burgard, Jonas, Grünwald‐Gruber, Clemens, Altmann, Friedrich, Zanghellini, Jürgen, Valli, Minoska, Mattanovich, Diethard, Gasser, Brigitte
Publicado 2019