MLH1 Region Polymorphisms Show a Significant Association with CpG Island Shore Methylation in a Large Cohort of Healthy Individuals

por Savio, Andrea J., Lemire, Mathieu, Mrkonjic, Miralem, Gallinger, Steven, Zanke, Brent W., Hudson, Thomas J., Bapat, Bharati
Publicado 2012

CFH and ARMS2 genetic risk determines progression to neovascular age-related macular degeneration after antioxidant and zinc supplementation

por Vavvas, Demetrios G., Small, Kent W., Awh, Carl C., Zanke, Brent W., Tibshirani, Robert J., Kustra, Rafal
Publicado 2018

Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray

por Chen, Yi-an, Lemire, Mathieu, Choufani, Sanaa, Butcher, Darci T., Grafodatskaya, Daria, Zanke, Brent W., Gallinger, Steven, Hudson, Thomas J., Weksberg, Rosanna
Publicado 2013

The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer

por Hawken, Steven J., Greenwood, Celia M. T., Hudson, Thomas J., Kustra, Rafal, McLaughlin, John, Yang, Quanhe, Zanke, Brent W., Little, Julian
Publicado 2010

Functional normalization of 450k methylation array data improves replication in large cancer studies

por Fortin, Jean-Philippe, Labbe, Aurélie, Lemire, Mathieu, Zanke, Brent W, Hudson, Thomas J, Fertig, Elana J, Greenwood, Celia MT, Hansen, Kasper D
Publicado 2014

Long-range epigenetic regulation is conferred by genetic variation located at thousands of independent loci

por Lemire, Mathieu, Zaidi, Syed H.E., Ban, Maria, Ge, Bing, Aïssi, Dylan, Germain, Marine, Kassam, Irfahan, Wang, Mike, Zanke, Brent W., Gagnon, France, Morange, Pierre-Emmanuel, Trégouët, David-Alexandre, Wells, Philip S., Sawcer, Stephen, Gallinger, Steven, Pastinen, Tomi, Hudson, Thomas J.
Publicado 2015

Specific Variants in the MLH1 Gene Region May Drive DNA Methylation, Loss of Protein Expression, and MSI-H Colorectal Cancer

por Mrkonjic, Miralem, Roslin, Nicole M., Greenwood, Celia M., Raptis, Stavroula, Pollett, Aaron, Laird, Peter W., Pethe, Vaijayanti V., Chiang, Theodore, Daftary, Darshana, Dicks, Elizabeth, Thibodeau, Stephen N., Gallinger, Steven, Parfrey, Patrick S., Younghusband, H. Banfield, Potter, John D., Hudson, Thomas J., McLaughlin, John R., Green, Roger C., Zanke, Brent W., Newcomb, Polly A., Paterson, Andrew D., Bapat, Bharati
Publicado 2010

Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants

por Peltekova, Vanya D, Lemire, Mathieu, Qazi, Aamer M, Zaidi, Syed H E, Trinh, Quang M, Bielecki, Ryszard, Rogers, Marianne, Hodgson, Lyndsey, Wang, Mike, D’Souza, David J A, Zandi, Sasan, Chong, Taryne, Kwan, Jennifer Y Y, Kozak, Krystian, De Borja, Richard, Timms, Lee, Rangrej, Jagadish, Volar, Milica, Chan-Seng-Yue, Michelle, Beck, Timothy, Ash, Colleen, Lee, Shawna, Wang, Jianxin, Boutros, Paul C, Stein, Lincoln D, Dick, John E, Gryfe, Robert, McPherson, John D, Zanke, Brent W, Pollett, Aaron, Gallinger, Steven, Hudson, Thomas J
Publicado 2014

Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A

por Wang, Hansong, Burnett, Terrilea, Kono, Suminori, Haiman, Christopher A., Iwasaki, Motoki, Wilkens, Lynne R., Loo, Lenora W.M., Berg, David Van Den, Kolonel, Laurence N., Henderson, Brian E., Keku, Temitope O., Sandler, Robert S., Signorello, Lisa B., Blot, William J., Newcomb, Polly A., Pande, Mala, Amos, Christopher I., West, Dee W., Bézieau, Stéphane, Berndt, Sonja I., Zanke, Brent W., Hsu, Li, Lindor, Noralane M., Haile, Robert W., Hopper, John L., Jenkins, Mark A., Gallinger, Steven, Casey, Graham, Stenzel, Stephanie L., Schumacher, Fredrick R., Peters, Ulrike, Gruber, Stephen B., Tsugane, Shoichiro, Stram, Daniel O., Marchand, Loïc Le
Publicado 2014

Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data

por Bien, Stephanie A., Auer, Paul L., Harrison, Tabitha A., Qu, Conghui, Connolly, Charles M., Greenside, Peyton G., Chen, Sai, Berndt, Sonja I., Bézieau, Stéphane, Kang, Hyun M., Huyghe, Jeroen, Brenner, Hermann, Casey, Graham, Chan, Andrew T., Hopper, John L., Banbury, Barbara L., Chang-Claude, Jenny, Chanock, Stephen J., Haile, Robert W., Hoffmeister, Michael, Fuchsberger, Christian, Jenkins, Mark A., Leal, Suzanne M., Lemire, Mathieu, Newcomb, Polly A., Gallinger, Steven, Potter, John D., Schoen, Robert E., Slattery, Martha L., Smith, Joshua D., Le Marchand, Loic, White, Emily, Zanke, Brent W., Abeçasis, Goncalo R., Carlson, Christopher S., Peters, Ulrike, Nickerson, Deborah A., Kundaje, Anshul, Hsu, Li
Publicado 2017

Genome-Wide Search for Gene-Gene Interactions in Colorectal Cancer

por Jiao, Shuo, Hsu, Li, Berndt, Sonja, Bézieau, Stéphane, Brenner, Hermann, Buchanan, Daniel, Caan, Bette J., Campbell, Peter T., Carlson, Christopher S., Casey, Graham, Chan, Andrew T., Chang-Claude, Jenny, Chanock, Stephen, Conti, David V., Curtis, Keith R., Duggan, David, Gallinger, Steven, Gruber, Stephen B., Harrison, Tabitha A., Hayes, Richard B., Henderson, Brian E., Hoffmeister, Michael, Hopper, John L., Hudson, Thomas J., Hutter, Carolyn M., Jackson, Rebecca D., Jenkins, Mark A., Kantor, Elizabeth D., Kolonel, Laurence N., Küry, Sébastien, Le Marchand, Loic, Lemire, Mathieu, Newcomb, Polly A., Potter, John D., Qu, Conghui, Rosse, Stephanie A., Schoen, Robert E., Schumacher, Fred R., Seminara, Daniela, Slattery, Martha L., Ulrich, Cornelia M., Zanke, Brent W., Peters, Ulrike
Publicado 2012

Genome-Wide Diet-Gene Interaction Analyses for Risk of Colorectal Cancer

por Figueiredo, Jane C., Hsu, Li, Hutter, Carolyn M., Lin, Yi, Campbell, Peter T., Baron, John A., Berndt, Sonja I., Jiao, Shuo, Casey, Graham, Fortini, Barbara, Chan, Andrew T., Cotterchio, Michelle, Lemire, Mathieu, Gallinger, Steven, Harrison, Tabitha A., Le Marchand, Loic, Newcomb, Polly A., Slattery, Martha L., Caan, Bette J., Carlson, Christopher S., Zanke, Brent W., Rosse, Stephanie A., Brenner, Hermann, Giovannucci, Edward L., Wu, Kana, Chang-Claude, Jenny, Chanock, Stephen J., Curtis, Keith R., Duggan, David, Gong, Jian, Haile, Robert W., Hayes, Richard B., Hoffmeister, Michael, Hopper, John L., Jenkins, Mark A., Kolonel, Laurence N., Qu, Conghui, Rudolph, Anja, Schoen, Robert E., Schumacher, Fredrick R., Seminara, Daniela, Stelling, Deanna L., Thibodeau, Stephen N., Thornquist, Mark, Warnick, Greg S., Henderson, Brian E., Ulrich, Cornelia M., Gauderman, W. James, Potter, John D., White, Emily, Peters, Ulrike
Publicado 2014

Genome-wide meta-analysis of common variant differences between men and women

por Boraska, Vesna, Jerončić, Ana, Colonna, Vincenza, Southam, Lorraine, Nyholt, Dale R., William Rayner, Nigel, Perry, John R.B., Toniolo, Daniela, Albrecht, Eva, Ang, Wei, Bandinelli, Stefania, Barbalic, Maja, Barroso, Inês, Beckmann, Jacques S., Biffar, Reiner, Boomsma, Dorret, Campbell, Harry, Corre, Tanguy, Erdmann, Jeanette, Esko, Tõnu, Fischer, Krista, Franceschini, Nora, Frayling, Timothy M., Girotto, Giorgia, Gonzalez, Juan R., Harris, Tamara B., Heath, Andrew C., Heid, Iris M., Hoffmann, Wolfgang, Hofman, Albert, Horikoshi, Momoko, Hua Zhao, Jing, Jackson, Anne U., Hottenga, Jouke-Jan, Jula, Antti, Kähönen, Mika, Khaw, Kay-Tee, Kiemeney, Lambertus A., Klopp, Norman, Kutalik, Zoltán, Lagou, Vasiliki, Launer, Lenore J., Lehtimäki, Terho, Lemire, Mathieu, Lokki, Marja-Liisa, Loley, Christina, Luan, Jian'an, Mangino, Massimo, Mateo Leach, Irene, Medland, Sarah E., Mihailov, Evelin, Montgomery, Grant W., Navis, Gerjan, Newnham, John, Nieminen, Markku S., Palotie, Aarno, Panoutsopoulou, Kalliope, Peters, Annette, Pirastu, Nicola, Polašek, Ozren, Rehnström, Karola, Ripatti, Samuli, Ritchie, Graham R.S., Rivadeneira, Fernando, Robino, Antonietta, Samani, Nilesh J., Shin, So-Youn, Sinisalo, Juha, Smit, Johannes H., Soranzo, Nicole, Stolk, Lisette, Swinkels, Dorine W., Tanaka, Toshiko, Teumer, Alexander, Tönjes, Anke, Traglia, Michela, Tuomilehto, Jaakko, Valsesia, Armand, van Gilst, Wiek H., van Meurs, Joyce B.J., Smith, Albert Vernon, Viikari, Jorma, Vink, Jacqueline M., Waeber, Gerard, Warrington, Nicole M., Widen, Elisabeth, Willemsen, Gonneke, Wright, Alan F., Zanke, Brent W., Zgaga, Lina, Boehnke, Michael, d'Adamo, Adamo Pio, de Geus, Eco, Demerath, Ellen W., den Heijer, Martin, Eriksson, Johan G., Ferrucci, Luigi, Gieger, Christian, Gudnason, Vilmundur, Hayward, Caroline, Hengstenberg, Christian, Hudson, Thomas J., Järvelin, Marjo-Riitta, Kogevinas, Manolis, Loos, Ruth J.F., Martin, Nicholas G., Metspalu, Andres, Pennell, Craig E., Penninx, Brenda W., Perola, Markus, Raitakari, Olli, Salomaa, Veikko, Schreiber, Stefan, Schunkert, Heribert, Spector, Tim D., Stumvoll, Michael, Uitterlinden, André G., Ulivi, Sheila, van der Harst, Pim, Vollenweider, Peter, Völzke, Henry, Wareham, Nicholas J., Wichmann, H.-Erich, Wilson, James F., Rudan, Igor, Xue, Yali, Zeggini, Eleftheria
Publicado 2012

Discovery of common and rare genetic risk variants for colorectal cancer

por Huyghe, Jeroen R, Bien, Stephanie A, Harrison, Tabitha A, Kang, Hyun Min, Chen, Sai, Schmit, Stephanie L, Conti, David V, Qu, Conghui, Jeon, Jihyoun, Edlund, Christopher K, Greenside, Peyton, Wainberg, Michael, Schumacher, Fredrick R, Smith, Joshua D, Levine, David M, Nelson, Sarah C, Sinnott-Armstrong, Nasa A, Albanes, Demetrius, Alonso, M Henar, Anderson, Kristin, Arnau-Collell, Coral, Arndt, Volker, Bamia, Christina, Banbury, Barbara L, Baron, John A, Berndt, Sonja I, Bézieau, Stéphane, Bishop, D Timothy, Boehm, Juergen, Boeing, Heiner, Brenner, Hermann, Brezina, Stefanie, Buch, Stephan, Buchanan, Daniel D, Burnett-Hartman, Andrea, Butterbach, Katja, Caan, Bette J, Campbell, Peter T, Carlson, Christopher S, Castellví-Bel, Sergi, Chan, Andrew T, Chang-Claude, Jenny, Chanock, Stephen J, Chirlaque, Maria-Dolores, Cho, Sang Hee, Connolly, Charles M, Cross, Amanda J, Cuk, Katarina, Curtis, Keith R, de la Chapelle, Albert, Doheny, Kimberly F, Duggan, David, Easton, Douglas F, Elias, Sjoerd G, Elliott, Faye, English, Dallas R, Feskens, Edith JM, Figueiredo, Jane C, Fischer, Rocky, FitzGerald, Liesel M, Forman, David, Gala, Manish, Gallinger, Steven, Gauderman, W James, Giles, Graham G, Gillanders, Elizabeth, Gong, Jian, Goodman, Phyllis J, Grady, William M, Grove, John S, Gsur, Andrea, Gunter, Marc J, Haile, Robert W, Hampe, Jochen, Hampel, Heather, Harlid, Sophia, Hayes, Richard B, Hofer, Philipp, Hoffmeister, Michael, Hopper, John L, Hsu, Wan-Ling, Huang, Wen-Yi, Hudson, Thomas J, Hunter, David J, Ibañez-Sanz, Gemma, Idos, Gregory E, Ingersoll, Roxann, Jackson, Rebecca D, Jacobs, Eric J, Jenkins, Mark A, Joshi, Amit D, Joshu, Corinne E, Keku, Temitope O, Key, Timothy J, Kim, Hyeong Rok, Kobayashi, Emiko, Kolonel, Laurence N, Kooperberg, Charles, Kühn, Tilman, Küry, Sébastien, Kweon, Sun-Seog, Larsson, Susanna C, Laurie, Cecelia A, Le Marchand, Loic, Leal, Suzanne M, Lee, Soo Chin, Lejbkowicz, Flavio, Lemire, Mathieu, Li, Christopher I, Li, Li, Lieb, Wolfgang, Lin, Yi, Lindblom, Annika, Lindor, Noralane M, Ling, Hua, Louie, Tin L, Männistö, Satu, Markowitz, Sanford D, Martín, Vicente, Masala, Giovanna, McNeil, Caroline E, Melas, Marilena, Milne, Roger L, Moreno, Lorena, Murphy, Neil, Myte, Robin, Naccarati, Alessio, Newcomb, Polly A, Offit, Kenneth, Ogino, Shuji, Onland-Moret, N Charlotte, Pardini, Barbara, Parfrey, Patrick S, Pearlman, Rachel, Perduca, Vittorio, Pharoah, Paul D P, Pinchev, Mila, Platz, Elizabeth A, Prentice, Ross L, Pugh, Elizabeth, Raskin, Leon, Rennert, Gad, Rennert, Hedy S, Riboli, Elio, Rodríguez-Barranco, Miguel, Romm, Jane, Sakoda, Lori C, Schafmayer, Clemens, Schoen, Robert E, Seminara, Daniela, Shah, Mitul, Shelford, Tameka, Shin, Min-Ho, Shulman, Katerina, Sieri, Sabina, Slattery, Martha L, Southey, Melissa C, Stadler, Zsofia K, Stegmaier, Christa, Su, Yu-Ru, Tangen, Catherine M, Thibodeau, Stephen N, Thomas, Duncan C, Thomas, Sushma S, Toland, Amanda E, Trichopoulou, Antonia, Ulrich, Cornelia M, Van Den Berg, David J, van Duijnhoven, Franzel JB, Van Guelpen, Bethany, van Kranen, Henk, Vijai, Joseph, Visvanathan, Kala, Vodicka, Pavel, Vodickova, Ludmila, Vymetalkova, Veronika, Weigl, Korbinian, Weinstein, Stephanie J, White, Emily, Win, Aung Ko, Wolf, C Roland, Wolk, Alicja, Woods, Michael O, Wu, Anna H, Zaidi, Syed H, Zanke, Brent W, Zhang, Qing, Zheng, Wei, Scacheri, Peter C, Potter, John D, Bassik, Michael C, Kundaje, Anshul, Casey, Graham, Moreno, Victor, Abecasis, Goncalo R, Nickerson, Deborah A, Gruber, Stephen B, Hsu, Li, Peters, Ulrike
Publicado 2018