The Traf2DNxBCL2-tg Mouse Model of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Recapitulates the Biased IGHV Gene Usage, Stereotypy, and Antigen-Specific HCDR3 Selectio...

por Perez-Chacon, Gema, Zapata, Juan M.
Publicado 2021

Editorial: Mouse Models of B Cell Malignancies

por Perez-Chacon, Gema, Vincent-Fabert, Christelle, Zapata, Juan M.
Publicado 2021

Dysregulated TRAF3 and BCL2 Expression Promotes Multiple Classes of Mature Non-hodgkin B Cell Lymphoma in Mice

por Perez-Chacon, Gema, Adrados, Magdalena, Vallejo-Cremades, Maria T., Lefebvre, Sophie, Reed, John C., Zapata, Juan M.
Publicado 2019

CD137 (4-1BB) Signalosome: Complexity Is a Matter of TRAFs

por Zapata, Juan M., Perez-Chacon, Gema, Carr-Baena, Pablo, Martinez-Forero, Ivan, Azpilikueta, Arantza, Otano, Itziar, Melero, Ignacio
Publicado 2018

Fludarabine Inhibits K(V)1.3 Currents in Human B Lymphocytes

por de la Cruz, Alicia, Vera-Zambrano, Alba, Peraza, Diego A., Valenzuela, Carmen, Zapata, Juan M., Perez-Chacon, Gema, Gonzalez, Teresa
Publicado 2017

Triterpenoids Display Single Agent Anti-tumor Activity in a Transgenic Mouse Model of Chronic Lymphocytic Leukemia and Small B Cell Lymphoma

por Kress, Christina L., Konopleva, Marina, Martínez-García, Vanesa, Krajewska, Maryla, Lefebvre, Sophie, Hyer, Marc L., McQueen, Teresa, Andreeff, Michael, Reed, John C., Zapata, Juan M.
Publicado 2007

CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110

por Domínguez, Juan Manuel, Pérez-Chacón, Gema, Guillén, María José, Muñoz-Alonso, María José, Somovilla-Crespo, Beatriz, Cibrián, Danay, Acosta-Iborra, Bárbara, Adrados, Magdalena, Muñoz-Calleja, Cecilia, Cuevas, Carmen, Sánchez-Madrid, Francisco, Avilés, Pablo, Zapata, Juan M.
Publicado 2020

Case Report: An EGFR-Targeted 4-1BB-agonistic Trimerbody Does Not Induce Hepatotoxicity in Transgenic Mice With Liver Expression of Human EGFR

por Compte, Marta, Harwood, Seandean L., Martínez-Torrecuadrada, Jorge, Perez-Chacon, Gema, González-García, Patricia, Tapia-Galisteo, Antonio, Van Bergen en Henegouwen, Paul M. P., Sánchez, Aránzazu, Fabregat, Isabel, Sanz, Laura, Zapata, Juan M., Alvarez-Vallina, Luis
Publicado 2021

Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma

por Somovilla-Crespo, Beatriz, Alfonso-Pérez, Manuel, Cuesta-Mateos, Carlos, Carballo-de Dios, Cristina, Beltrán, Amada E, Terrón, Fernando, Pérez-Villar, Juan J, Gamallo-Amat, Carlos, Pérez-Chacón, Gema, Fernández-Ruiz, Elena, Zapata, Juan M, Muñoz-Calleja, Cecilia
Publicado 2013

Down-regulation of oxidative phosphorylation in the liver by expression of the ATPase inhibitory factor 1 induces a tumor-promoter metabolic state

por Santacatterina, Fulvio, Sánchez-Cenizo, Laura, Formentini, Laura, Mobasher, Maysa A., Casas, Estela, Rueda, Carlos B., Martínez-Reyes, Inmaculada, de Arenas, Cristina Núñez, García-Bermúdez, Javier, Zapata, Juan M., Sánchez-Aragó, María, Satrústegui, Jorgina, Valverde, Ángela M., Cuezva, José M.
Publicado 2015

A tumor-targeted trimeric 4-1BB-agonistic antibody induces potent anti-tumor immunity without systemic toxicity

por Compte, Marta, Harwood, Seandean Lykke, Muñoz, Ines G., Navarro, Rocio, Zonca, Manuela, Perez-Chacon, Gema, Erce-Llamazares, Ainhoa, Merino, Nekane, Tapia-Galisteo, Antonio, Cuesta, Angel M., Mikkelsen, Kasper, Caleiras, Eduardo, Nuñez-Prado, Natalia, Aznar, M. Angela, Lykkemark, Simon, Martínez-Torrecuadrada, Jorge, Melero, Ignacio, Blanco, Francisco J., Bernardino de la Serna, Jorge, Zapata, Juan M., Sanz, Laura, Alvarez-Vallina, Luis
Publicado 2018