The efficacy of receptor tyrosine kinase EphA2 autophosphorylation increases with EphA2 oligomer size

por Zapata-Mercado, Elmer, Biener, Gabriel, McKenzie, Daniel M., Wimley, William C., Pasquale, Elena B., Raicu, Valerica, Hristova, Kalina
Publicado 2022

Ligands with different dimeric configurations potently activate the EphA2 receptor and reveal its potential for biased signaling

por Gomez-Soler, Maricel, Gehring, Marina P., Lechtenberg, Bernhard C., Zapata-Mercado, Elmer, Ruelos, Alyssa, Matsumoto, Mike W., Hristova, Kalina, Pasquale, Elena B.
Publicado 2022

A cancer mutation promotes EphA4 oligomerization and signaling by altering the conformation of the SAM domain

por Light, Taylor P., Gomez-Soler, Maricel, Wang, Zichen, Karl, Kelly, Zapata-Mercado, Elmer, Gehring, Marina P., Lechtenberg, Bernhard C., Pogorelov, Taras V., Hristova, Kalina, Pasquale, Elena B.
Publicado 2021