Atorvastatin (Lipitor) by MCR

por Zarganes-Tzitzikas, Tryfon, Neochoritis, Constantinos G., Dömling, Alexander
Publicado 2019

MCR Scaffolds Get Hotter with (18)F-Labeling

por Zarganes-Tzitzikas, Tryfon, Clemente, Gonçalo S., Elsinga, Philip H., Dömling, Alexander
Publicado 2019

Late-Stage Copper-Catalyzed Radiofluorination of an Arylboronic Ester Derivative of Atorvastatin

por S. Clemente, Gonçalo, Zarganes-Tzitzikas, Tryfon, Dömling, Alexander, H. Elsinga, Philip
Publicado 2019

Multicomponent Reactions: “Kinderleicht”

por Neochoritis, Constantinos G., Zarganes-Tzitzikas, Tryfon, Katsampoxaki-Hodgetts, Kallia, Dömling, Alexander
Publicado 2020

Application of Silver Nanoparticles in the Multicomponent Reaction Domain: A Combined Catalytic Reduction Methodology to Efficiently Access Potential Hypertension or Inflammation I...

por Iordanidou, Domna, Zarganes-Tzitzikas, Tryfon, Neochoritis, Constantinos G., Dömling, Alexander, Lykakis, Ioannis N.
Publicado 2018

Synthesis of Highly Substituted Imidazole Uracil Containing Molecules via Ugi-4CR and Passerini-3CR

por Madhavachary, Rudrakshula, Zarganes-Tzitzikas, Tryfon, Patil, Pravin, Kurpiewska, Katarzyna, Kalinowska-Tłuścik, Justyna, Dömling, Alexander
Publicado 2018

Multicomponent reaction–derived covalent inhibitor space

por Sutanto, Fandi, Shaabani, Shabnam, Neochoritis, Constantinos G., Zarganes-Tzitzikas, Tryfon, Patil, Pravin, Ghonchepour, Ehsan, Dömling, Alexander
Publicado 2021

[(18)F]Atorvastatin: synthesis of a potential molecular imaging tool for the assessment of statin-related mechanisms of action

por Clemente, Gonçalo S., Rickmeier, Jens, Antunes, Inês F., Zarganes-Tzitzikas, Tryfon, Dömling, Alexander, Ritter, Tobias, Elsinga, Philip H.
Publicado 2020

Nanoscale, automated, high throughput synthesis and screening for the accelerated discovery of protein modifiers

por Gao, Kai, Shaabani, Shabnam, Xu, Ruixue, Zarganes-Tzitzikas, Tryfon, Gao, Li, Ahmadianmoghaddam, Maryam, Groves, Matthew R., Dömling, Alexander
Publicado 2021

Design of indole- and MCR-based macrocycles as p53-MDM2 antagonists

por Neochoritis, Constantinos G, Kazemi Miraki, Maryam, Abdelraheem, Eman M M, Surmiak, Ewa, Zarganes-Tzitzikas, Tryfon, Łabuzek, Beata, Holak, Tad A, Dömling, Alexander
Publicado 2019

Inhibition of the NLRP3 inflammasome by HSP90 inhibitors

por Nizami, Sohaib, Arunasalam, Kanisa, Green, Jack, Cook, James, Lawrence, Catherine B., Zarganes‐Tzitzikas, Tryfon, Davis, John B., Di Daniel, Elena, Brough, David
Publicado 2020

Discovery and Development Strategies for SARS-CoV-2 NSP3 Macrodomain Inhibitors

por Schuller, Marion, Zarganes-Tzitzikas, Tryfon, Bennett, James, De Cesco, Stephane, Fearon, Daren, von Delft, Frank, Fedorov, Oleg, Brennan, Paul E., Ahel, Ivan
Publicado 2023

A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation

por Nizami, Sohaib, Millar, Val, Arunasalam, Kanisa, Zarganes-Tzitzikas, Tryfon, Brough, David, Tresadern, Gary, Brennan, Paul E., Davis, John B., Ebner, Daniel, Di Daniel, Elena
Publicado 2021

Author Correction: A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation

por Nizami, Sohaib, Millar, Val, Arunasalam, Kanisa, Zarganes-Tzitzikas, Tryfon, Brough, David, Tresadern, Gary, Brennan, Paul E., Davis, John B., Ebner, Daniel, Di Daniel, Elena
Publicado 2021

Supported Gold Nanoparticle-Catalyzed Selective Reduction of Multifunctional, Aromatic Nitro Precursors into Amines and Synthesis of 3,4-Dihydroquinoxalin-2-Ones

por Iordanidou, Domna, Kallitsakis, Michael G., Tzani, Marina A., Ioannou, Dimitris I., Zarganes-Tzitzikas, Tryfon, Neochoritis, Constantinos G., Dömling, Alexander, Terzidis, Michael A., Lykakis, Ioannis N.
Publicado 2022

Biphenyl Ether Analogs Containing Pomalidomide as Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction

por Shaabani, Shabnam, Gadina, Louis, Surmiak, Ewa, Wang, Zefeng, Zhang, Bidong, Butera, Roberto, Zarganes-Tzitzikas, Tryfon, Rodriguez, Ismael, Kocik-Krol, Justyna, Magiera-Mularz, Katarzyna, Skalniak, Lukasz, Dömling, Alexander, Holak, Tad A.
Publicado 2022

Rapid approach to complex boronic acids

por Neochoritis, Constantinos G., Shaabani, Shabnam, Ahmadianmoghaddam, Maryam, Zarganes-Tzitzikas, Tryfon, Gao, Li, Novotná, Michaela, Mitríková, Tatiana, Romero, Atilio Reyes, Irianti, Marina Ika, Xu, Ruixue, Olechno, Joe, Ellson, Richard, Helan, Victoria, Kossenjans, Michael, Groves, Matthew R., Dömling, Alexander
Publicado 2019

Design, Synthesis, and Biological Evaluation of 2-Hydroxy-4-phenylthiophene-3-carbonitrile as PD-L1 Antagonist and Its Comparison to Available Small Molecular PD-L1 Inhibitors

por Ważyńska, Marta A., Butera, Roberto, Requesens, Marta, Plat, Annechien, Zarganes-Tzitzikas, Tryfon, Neochoritis, Constantinos G., Plewka, Jacek, Skalniak, Lukasz, Kocik-Krol, Justyna, Musielak, Bogdan, Magiera-Mularz, Katarzyna, Rodriguez, Ismael, Blok, Simon N., de Bruyn, Marco, Nijman, Hans W., Elsinga, Philip H., Holak, Tad A., Dömling, Alexander
Publicado 2023

TEAD–YAP Interaction Inhibitors and MDM2 Binders from DNA‐Encoded Indole‐Focused Ugi Peptidomimetics

por Kunig, Verena B. K., Potowski, Marco, Akbarzadeh, Mohammad, Klika Škopić, Mateja, dos Santos Smith, Denise, Arendt, Lukas, Dormuth, Ina, Adihou, Hélène, Andlovic, Blaž, Karatas, Hacer, Shaabani, Shabnam, Zarganes‐Tzitzikas, Tryfon, Neochoritis, Constantinos G., Zhang, Ran, Groves, Matthew, Guéret, Stéphanie M., Ottmann, Christian, Rahnenführer, Jörg, Fried, Roland, Dömling, Alexander, Brunschweiger, Andreas
Publicado 2020