Think globally, act locally: Centrosome-localized mRNAs ensure mitotic fidelity

por Zarnescu, Daniela C.
Publicado 2020

Apical Spectrin Is Essential for Epithelial Morphogenesis but Not Apicobasal Polarity in Drosophila

por Zarnescu, Daniela C., Thomas, Claire M
Publicado 1999

A Helping Hand: RNA-Binding Proteins Guide Gene-Binding Choices by Cohesin Complexes

por Coyne, Alyssa N., Zarnescu, Daniela C.
Publicado 2016

Failure to Deliver and Translate—New Insights into RNA Dysregulation in ALS

por Coyne, Alyssa N., Zaepfel, Benjamin L., Zarnescu, Daniela C.
Publicado 2017

Dysregulation of Translation in TDP-43 Proteinopathies: Deficits in the RNA Supply Chain and Local Protein Production

por Bjork, Reed T., Mortimore, Nicholas P., Loganathan, Suvithanandhini, Zarnescu, Daniela C.
Publicado 2022

Regulation of Heart Rate in Drosophila via Fragile X Mental Retardation Protein

por Novak, Stefanie Mares, Joardar, Archi, Gregorio, Carol C., Zarnescu, Daniela C.
Publicado 2015

­2019 PLOS Genetics Research Prize: Fruit fly school – language and dialects for communicating a threat

por Barsh, Gregory S., Copenhaver, Gregory P., Prakash, Elapulli Sankaranarayanan, Zarnescu, Daniela C.
Publicado 2019

To Be or Not To Be…Toxic—Is RNA Association With TDP-43 Complexes Deleterious or Protective in Neurodegeneration?

por Loganathan, Suvithanandhini, Lehmkuhl, Erik M., Eck, Randall J., Zarnescu, Daniela C.
Publicado 2020

Genetic and systems level analysis of Drosophila sticky/citron kinase and dFmr1 mutants reveals common regulation of genetic networks

por Bauer, Christopher R, Epstein, Andrew M, Sweeney, Sarah J, Zarnescu, Daniela C, Bosco, Giovanni
Publicado 2008

Endocytosis regulates TDP-43 toxicity and turnover

por Liu, Guangbo, Coyne, Alyssa N., Pei, Fen, Vaughan, Spencer, Chaung, Matthew, Zarnescu, Daniela C., Buchan, J. Ross
Publicado 2017

TDP-43 Proteinopathy Causes Broad Metabolic Alterations including TCA Cycle Intermediates and Dopamine Levels in Drosophila Models of ALS

por Loganathan, Suvithanandhini, Wilson, Bryce A., Carey, Sara B., Manzo, Ernesto, Joardar, Archi, Ugur, Berrak, Zarnescu, Daniela C.
Publicado 2022

Medium-Chain Fatty Acids, Beta-Hydroxybutyric Acid and Genetic Modulation of the Carnitine Shuttle Are Protective in a Drosophila Model of ALS Based on TDP-43

por Manzo, Ernesto, O'Conner, Abigail G., Barrows, Jordan M., Shreiner, Dakotah D., Birchak, Gabriel J., Zarnescu, Daniela C.
Publicado 2018

Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis

por Estes, Patricia S., Daniel, Scott G., Mccallum, Abigail P., Boehringer, Ashley V., Sukhina, Alona S., Zwick, Rebecca A., Zarnescu, Daniela C.
Publicado 2013

miR-9a mediates the role of Lethal giant larvae as an epithelial growth inhibitor in Drosophila

por Daniel, Scott G., Russ, Atlantis D., Guthridge, Kathryn M., Raina, Ammad I., Estes, Patricia S., Parsons, Linda M., Richardson, Helena E., Schroeder, Joyce A., Zarnescu, Daniela C.
Publicado 2017

Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS

por Manzo, Ernesto, Lorenzini, Ileana, Barrameda, Dianne, O'Conner, Abigail G, Barrows, Jordan M, Starr, Alexander, Kovalik, Tina, Rabichow, Benjamin E, Lehmkuhl, Erik M, Shreiner, Dakotah D, Joardar, Archi, Liévens, Jean-Charles, Bowser, Robert, Sattler, Rita, Zarnescu, Daniela C
Publicado 2019

Modelling TDP-43 proteinopathy in Drosophila uncovers shared and neuron-specific targets across ALS and FTD relevant circuits

por Godfrey, R. Keating, Alsop, Eric, Bjork, Reed T., Chauhan, Brijesh S., Ruvalcaba, Hillary C., Antone, Jerry, Gittings, Lauren M., Michael, Allison F., Williams, Christi, Hala’ufia, Grace, Blythe, Alexander D., Hall, Megan, Sattler, Rita, Van Keuren-Jensen, Kendall, Zarnescu, Daniela C.
Publicado 2023

TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6

por Lehmkuhl, Erik M., Loganathan, Suvithanandhini, Alsop, Eric, Blythe, Alexander D., Kovalik, Tina, Mortimore, Nicholas P., Barrameda, Dianne, Kueth, Chuol, Eck, Randall J., Siddegowda, Bhavani B., Joardar, Archi, Ball, Hannah, Macias, Maria E., Bowser, Robert, Van Keuren-Jensen, Kendall, Zarnescu, Daniela C.
Publicado 2021

The M1311V variant of ATP7A is associated with impaired trafficking and copper homeostasis in models of motor neuron disease

por Bakkar, Nadine, Starr, Alexander, Rabichow, Benjamin E., Lorenzini, Ileana, McEachin, Zachary T., Kraft, Robert, Chaung, Matthew, Macklin-Isquierdo, Sam, Wingfield, Taylor, Carhart, Briggs, Zahler, Nathan, Chang, Wen-Hsuan, Bassell, Gary J., Betourne, Alexandre, Boulis, Nicholas, Alworth, Samuel V., Ichida, Justin K., August, Paul R., Zarnescu, Daniela C., Sattler, Rita, Bowser, Robert
Publicado 2021

TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD

por Chou, Ching-Chieh, Zhang, Yi, Umoh, Mfon E., Vaughan, Spencer W., Lorenzini, Ileana, Liu, Feilin, Sayegh, Melissa, Donlin-Asp, Paul G., Chen, Yu Han, Duong, Duc M., Seyfried, Nicholas T., Powers, Maureen A., Kukar, Thomas, Hales, Chadwick M., Gearing, Marla, Cairns, Nigel J., Boylan, Kevin B., Dickson, Dennis W., Rademakers, Rosa, Zhang, Yong-Jie, Petrucelli, Leonard, Sattler, Rita, Zarnescu, Daniela C., Glass, Jonathan D., Rossoll, Wilfried
Publicado 2018