NPM1 mutation reprograms leukemic transcription network via reshaping TAD topology

por Lai, Qian, Hamamoto, Karina, Luo, Huacheng, Zaroogian, Zachary, Zhou, Caixian, Lesperance, Julia, Zha, Jie, Qiu, Yi, Guryanova, Olga A., Huang, Suming, Xu, Bing
Publicado 2023

P986: COMBINATION JAK1/2 AND CDK8/19 INHIBITION DEMONSTRATES ENHANCED EFFICACY IN MYELOPROLIFERATIVE NEOPLASMS

por Zaroogian, Zachary, Adamczyk, Elżbieta, Moszyńska, Adrianna, Obacz, Marta, Pakulska, Urszula, Durham, Benjamin, Mazan, Milena, Mowla, Shoron, Wnęk, Katarzyna, Somasundara, Amritha Varshini Hanasoge, Barczuk, Beata, Gołas, Aniela, Levine, Ross, Rzymski, Tomasz, Rampal, Raajit K
Publicado 2023

Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer

por Feng, Yang, Yuan, Qingchen, Newsome, Rachel C., Robinson, Troy, Bowman, Robert L., Zuniga, Ashley N., Hall, Kendra N., Bernsten, Cassandra M., Shabashvili, Daniil E., Krajcik, Kathryn I., Gunaratne, Chamara, Zaroogian, Zachary J., Venugopal, Kartika, Casellas Roman, Heidi L., Levine, Ross L., Chatila, Walid K., Yaeger, Rona, Riva, Alberto, Jobin, Christian, Kopinke, Daniel, Avram, Dorina, Guryanova, Olga A.
Publicado 2023

DNMT3A Harboring Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

por Venugopal, Kartika, Feng, Yang, Nowialis, Pawel, Xu, Huanzhou, Shabashvili, Daniil E., Berntsen, Cassandra M., Kaur, Prabhjot, Krajcik, Kathryn I., Taragjini, Christina, Zaroogian, Zachary, Casellas Román, Heidi L., Posada, Luisa M., Gunaratne, Chamara, Li, Jianping, Dupéré-Richer, Daphné, Bennett, Richard L., Pondugula, Santhi, Riva, Alberto, Cogle, Christopher R., Opavsky, Rene, Law, Brian K., Bhaduri-McIntosh, Sumita, Kubicek, Stefan, Staber, Philipp B., Licht, Jonathan D., Bird, Jonathan E., Guryanova, Olga A.
Publicado 2022