The ARF tumor suppressor prevents chromosomal instability and ensures mitotic checkpoint fidelity through regulation of Aurora B

por Britigan, Eric M.C., Wan, Jun, Zasadil, Lauren M., Ryan, Sean D., Weaver, Beth A.
Publicado 2014

Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer

por Denu, Ryan A., Zasadil, Lauren M., Kanugh, Craig, Laffin, Jennifer, Weaver, Beth A., Burkard, Mark E.
Publicado 2016

High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instabilit...

por Matson, Daniel R., Denu, Ryan A., Zasadil, Lauren M., Burkard, Mark E., Weaver, Beth A., Flynn, Christopher, Stukenberg, P. Todd
Publicado 2021

High rates of chromosome missegregation suppress tumor progression but do not inhibit tumor initiation

por Zasadil, Lauren M., Britigan, Eric M. C., Ryan, Sean D., Kaur, Charanjeet, Guckenberger, David J., Beebe, David J., Moser, Amy R., Weaver, Beth A.
Publicado 2016

Clonal selection of stable aneuploidies in progenitor cells drives high-prevalence tumorigenesis

por Trakala, Marianna, Aggarwal, Muskaan, Sniffen, Courtney, Zasadil, Lauren, Carroll, Allison, Ma, Duanduan, Su, Xiaofeng A., Wangsa, Darawalee, Meyer, Ashleigh, Sieben, Cynthia J., Zhong, Jian, Hsu, Pei-hsin, Paradis, Glenn, Ried, Thomas, Holland, Andrew, Van Deursen, Jan, Amon, Angelika
Publicado 2021