RTS,S: the first malaria vaccine

por Zavala, Fidel
Publicado 2022

Reply to Vanderberg, “Further Mechanisms and Locations in Which Antisporozoite Antibodies Neutralize Malaria Sporozoites”

por Sinnis, Photini, Zavala, Fidel
Publicado 2019

A chemokine-fusion vaccine targeting immature dendritic cells elicits elevated antibody responses to malaria sporozoites in infant macaques

por Luo, Kun, Gordy, James T., Zavala, Fidel, Markham, Richard B.
Publicado 2021

An epitope-based malaria vaccine targeting the junctional region of circumsporozoite protein

por Jelínková, Lucie, Jhun, Hugo, Eaton, Allison, Petrovsky, Nikolai, Zavala, Fidel, Chackerian, Bryce
Publicado 2021

Unique transcriptional profile of liver-resident memory CD8(+) T cells induced by immunization with malaria sporozoites

por Tse, Sze-Wah, Cockburn, Ian A., Zhang, Hao, Scott, Alan L., Zavala, Fidel
Publicado 2013

IL-4 receptor expression on CD8(+) T cells is required for the development of protective memory responses against liver stages of malaria parasites

por Morrot, Alexandre, Hafalla, Julius C.R., Cockburn, Ian A., Carvalho, Luzia H., Zavala, Fidel
Publicado 2005

CD4(+) T Cells Modulate Expansion and Survival but Not Functional Properties of Effector and Memory CD8(+) T Cells Induced by Malaria Sporozoites

por Overstreet, Michael G., Chen, Yun-Chi, Cockburn, Ian A., Tse, Sze-Wah, Zavala, Fidel
Publicado 2011

Fusion of Antigen to a Dendritic Cell Targeting Chemokine Combined with Adjuvant Yields a Malaria DNA Vaccine with Enhanced Protective Capabilities

por Luo, Kun, Zhang, Hong, Zavala, Fidel, Biragyn, Arya, Espinosa, Diego A., Markham, Richard B.
Publicado 2014

Robust antibody and CD8(+) T-cell responses induced by P. falciparum CSP adsorbed to cationic liposomal adjuvant CAF09 confer sterilizing immunity against experimental rodent malar...

por Espinosa, Diego A., Christensen, Dennis, Muñoz, Christian, Singh, Sanjay, Locke, Emily, Andersen, Peter, Zavala, Fidel
Publicado 2017

A vaccine targeting the L9 epitope of the malaria circumsporozoite protein confers protection from blood-stage infection in a mouse challenge model

por Jelínková, Lucie, Flores-Garcia, Yevel, Shapiro, Sarah, Roberts, Bryce T., Petrovsky, Nikolai, Zavala, Fidel, Chackerian, Bryce
Publicado 2022

Swift Development of Protective Effector Functions in Naive Cd8(+) T Cells against Malaria Liver Stages

por Sano, Gen-ichiro, Hafalla, Julius C.R., Morrot, Alexandre, Abe, Ryo, Lafaille, Juan J., Zavala, Fidel
Publicado 2001

Antibody-Mediated Protection against Plasmodium Sporozoites Begins at the Dermal Inoculation Site

por Flores-Garcia, Yevel, Nasir, Gibran, Hopp, Christine S., Munoz, Christian, Balaban, Amanda E., Zavala, Fidel, Sinnis, Photini
Publicado 2018

Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria

por Bijker, Else M, Nganou-Makamdop, Krystelle, van Gemert, Geert-Jan, Zavala, Fidel, Cockburn, Ian, Sauerwein, Robert W
Publicado 2015

Dendritic Cells and Hepatocytes Use Distinct Pathways to Process Protective Antigen from Plasmodium in vivo

por Cockburn, Ian A., Tse, Sze-Wah, Radtke, Andrea J., Srinivasan, Prakash, Chen, Yun-Chi, Sinnis, Photini, Zavala, Fidel
Publicado 2011

Prolonged Antigen Presentation Is Required for Optimal CD8+ T Cell Responses against Malaria Liver Stage Parasites

por Cockburn, Ian A., Chen, Yun-Chi, Overstreet, Michael G., Lees, Jason R., van Rooijen, Nico, Farber, Donna L., Zavala, Fidel
Publicado 2010

Optimization of an in vivo model to study immunity to Plasmodium falciparum pre-erythrocytic stages

por Flores-Garcia, Yevel, Herrera, Sonia M., Jhun, Hugo, Pérez-Ramos, Daniel W., King, C. Richter, Locke, Emily, Raghunandan, Ramadevi, Zavala, Fidel
Publicado 2019

P. falciparum and P. vivax Epitope-Focused VLPs Elicit Sterile Immunity to Blood Stage Infections

por Whitacre, David C., Espinosa, Diego A., Peters, Cory J., Jones, Joyce E., Tucker, Amy E., Peterson, Darrell L., Zavala, Fidel P., Milich, David R.
Publicado 2015

Lymph-Node Resident CD8α(+) Dendritic Cells Capture Antigens from Migratory Malaria Sporozoites and Induce CD8(+) T Cell Responses

por Radtke, Andrea J., Kastenmüller, Wolfgang, Espinosa, Diego A., Gerner, Michael Y., Tse, Sze-Wah, Sinnis, Photini, Germain, Ronald N., Zavala, Fidel P., Cockburn, Ian A.
Publicado 2015

Primaquine-thiazolidinones block malaria transmission and development of the liver exoerythrocytic forms

por Aguiar, Anna Caroline C., Figueiredo, Flávio Jr. B., Neuenfeldt, Patrícia D., Katsuragawa, Tony H., Drawanz, Bruna B., Cunico, Wilson, Sinnis, Photini, Zavala, Fidel, Krettli, Antoniana U.
Publicado 2017

Effective Functional Immunogenicity of a DNA Vaccine Combination Delivered via In Vivo Electroporation Targeting Malaria Infection and Transmission

por Cao, Yi, Hayashi, Clifford T. H., Zavala, Fidel, Tripathi, Abhai K., Simonyan, Hayk, Young, Colin N., Clark, Leor C., Usuda, Yukari, Van Parys, Jacob M., Kumar, Nirbhay
Publicado 2022