An improved statistical method to identify chemical-genetic interactions by exploiting concentration-dependence

por Dutta, Esha, DeJesus, Michael A., Ruecker, Nadine, Zaveri, Anisha, Koh, Eun-Ik, Sassetti, Christopher M., Schnappinger, Dirk, Ioerger, Thomas R.
Publicado 2021

Statistical analysis of variability in TnSeq data across conditions using zero-inflated negative binomial regression

por Subramaniyam, Siddharth, DeJesus, Michael A., Zaveri, Anisha, Smith, Clare M., Baker, Richard E., Ehrt, Sabine, Schnappinger, Dirk, Sassetti, Christopher M., Ioerger, Thomas R.
Publicado 2019

Depletion of the DarG antitoxin in Mycobacterium tuberculosis triggers the DNA‐damage response and leads to cell death

por Zaveri, Anisha, Wang, Ruojun, Botella, Laure, Sharma, Ritu, Zhu, Linnan, Wallach, Joshua B., Song, Naomi, Jansen, Robert S., Rhee, Kyu Y., Ehrt, Sabine, Schnappinger, Dirk
Publicado 2020

Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis

por Bosch, Barbara, DeJesus, Michael A., Poulton, Nicholas C., Zhang, Wenzhu, Engelhart, Curtis A., Zaveri, Anisha, Lavalette, Sophie, Ruecker, Nadine, Trujillo, Carolina, Wallach, Joshua B., Li, Shuqi, Ehrt, Sabine, Chait, Brian T., Schnappinger, Dirk, Rock, Jeremy M.
Publicado 2021

Chemical–genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy

por Koh, Eun-Ik, Oluoch, Peter O., Ruecker, Nadine, Proulx, Megan K., Soni, Vijay, Murphy, Kenan C., Papavinasasundaram, Kadamba, Reames, Charlotte J., Trujillo, Carolina, Zaveri, Anisha, Zimmerman, Matthew D., Aslebagh, Roshanak, Baker, Richard E., Shaffer, Scott A., Guinn, Kristine M., Fitzgerald, Michael, Dartois, Véronique, Ehrt, Sabine, Hung, Deborah T., Ioerger, Thomas R., Rubin, Eric J., Rhee, Kyu Y., Schnappinger, Dirk, Sassetti, Christopher M.
Publicado 2022