An in silico model of retinal cholesterol dynamics (RCD model): insights into the pathophysiology of dry AMD

por Zekavat, Seyedeh Maryam, Lu, James, Maugeais, Cyrille, Mazer, Norman A.
Publicado 2017

A computational model of 1,5‐AG dynamics during pregnancy

por Zekavat, Seyedeh M., Butkovich, Slava, Young, Grace J., Nathan, David M., Petrasek, Danny
Publicado 2017

Genome-wide pleiotropy analysis of coronary artery disease and pneumonia identifies shared immune pathways

por Yu, Zhi, Zekavat, Seyedeh M., Haidermota, Sara, Bernardo, Rachel, MacDonald, Bryan T., Libby, Peter, Finucane, Hilary K., Natarajan, Pradeep
Publicado 2022

Elevated Blood Pressure Increases Pneumonia Risk: Epidemiological Association and Mendelian Randomization in the UK Biobank

por Zekavat, Seyedeh M., Honigberg, Michael, Pirruccello, James P., Kohli, Puja, Karlson, Elizabeth W., Newton-Cheh, Christopher, Zhao, Hongyu, Natarajan, Pradeep
Publicado 2021

Genetics of smoking and risk of clonal hematopoiesis

por Levin, Michael G., Nakao, Tetsushi, Zekavat, Seyedeh M., Koyama, Satoshi, Bick, Alexander G., Niroula, Abhishek, Ebert, Benjamin, Damrauer, Scott M., Natarajan, Pradeep
Publicado 2022

Androgen Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men

por Ghazizadeh, Zaniar, Majd, Homa, Richter, Mikayla, Samuel, Ryan, Zekavat, Seyedeh Maryam, Asgharian, Hosseinali, Farahvashi, Sina, Kalantari, Ali, Ramirez, Jonathan, Zhao, Hongyu, Natarajan, Pradeep, Goodarzi, Hani, Fattahi, Faranak
Publicado 2020

Insights into human health from phenome- and genome-wide analyses of UK Biobank retinal optical coherence tomography phenotypes

por Zekavat, Seyedeh Maryam, Jorshery, Saman Doroodgar, Shweikh, Yusrah, Horn, Katrin, Rauscher, Franziska G., Sekimitsu, Sayuri, Kayoma, Satoshi, Ye, Yixuan, Raghu, Vineet, Zhao, Hongyu, Ghassemi, Marzyeh, Elze, Tobias, Segrè, Ayellet V., Wiggs, Janey L., Scholz, Markus, Priore, Lucian Del, Wang, Jay C., Natarajan, Pradeep, Zebardast, Nazlee
Publicado 2023

Recall by genotype and cascade screening for familial hypercholesterolemia in a population-based biobank from Estonia

por Alver, Maris, Palover, Marili, Saar, Aet, Läll, Kristi, Zekavat, Seyedeh Maryam, Tõnisson, Neeme, Leitsalu, Liis, Reigo, Anu, Nikopensius, Tiit, Ainla, Tiia, Kals, Mart, Mägi, Reedik, Gabriel, Stacey B., Eha, Jaan, Lander, Eric S., Irs, Alar, Philippakis, Anthony, Marandi, Toomas, Natarajan, Pradeep, Metspalu, Andres, Kathiresan, Sekar, Esko, Tõnu
Publicado 2018

Deep Learning of the Retina Enables Phenome- and Genome-Wide Analyses of the Microvasculature

por Zekavat, Seyedeh Maryam, Raghu, Vineet K., Trinder, Mark, Ye, Yixuan, Koyama, Satoshi, Honigberg, Michael C., Yu, Zhi, Pampana, Akhil, Urbut, Sarah, Haidermota, Sara, O’Regan, Declan P., Zhao, Hongyu, Ellinor, Patrick T., Segrè, Ayellet V., Elze, Tobias, Wiggs, Janey L., Martone, James, Adelman, Ron A., Zebardast, Nazlee, Del Priore, Lucian, Wang, Jay C., Natarajan, Pradeep
Publicado 2021

Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men

por Samuel, Ryan M., Majd, Homa, Richter, Mikayla N., Ghazizadeh, Zaniar, Zekavat, Seyedeh Maryam, Navickas, Albertas, Ramirez, Jonathan T., Asgharian, Hosseinali, Simoneau, Camille R., Bonser, Luke R., Koh, Kyung Duk, Garcia-Knight, Miguel, Tassetto, Michel, Sunshine, Sara, Farahvashi, Sina, Kalantari, Ali, Liu, Wei, Andino, Raul, Zhao, Hongyu, Natarajan, Pradeep, Erle, David J., Ott, Melanie, Goodarzi, Hani, Fattahi, Faranak
Publicado 2020

Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer

por Natarajan, Pradeep, Zekavat, Seyedeh, Lin, Shu-Hong, Bick, Alexander, Liu, Aoxing, Paruchuri, Kaavya, Uddin, Md Mesbah, Ye, Yixuan, Yu, Zhaolong, Liu, Xiaoxi, Kamatani, Yoichiro, Pirruccello, James, Pampana, Akhil, Loh, Po-Ru, Kohli, Puja, McCarroll, Steven, Neale, Benjamin, Engels, Eric, Brown, Derek, Smoller, Jordan, Green, Robert, Karlson, Elizabeth, Lebo, Matthew, Ellinor, Patrick, Weiss, Scott, Daly, Mark, Terao, Chikashi, Zhao, Hongyu, Ebert, Benjamin, Machiela, Mitchell, Genovese, Giulio
Publicado 2020

Genetic modification of inflammation- and clonal hematopoiesis–associated cardiovascular risk

por Yu, Zhi, Fidler, Trevor P., Ruan, Yunfeng, Vlasschaert, Caitlyn, Nakao, Tetsushi, Uddin, Md Mesbah, Mack, Taralynn, Niroula, Abhishek, Heimlich, J. Brett, Zekavat, Seyedeh M., Gibson, Christopher J., Griffin, Gabriel K., Wang, Yuxuan, Peloso, Gina M., Heard-Costa, Nancy, Levy, Daniel, Vasan, Ramachandran S., Aguet, François, Ardlie, Kristin G., Taylor, Kent D., Rich, Stephen S., Rotter, Jerome I., Libby, Peter, Jaiswal, Siddhartha, Ebert, Benjamin L., Bick, Alexander G., Tall, Alan R., Natarajan, Pradeep
Publicado 2023

Ultra-rare disruptive and damaging mutations influence educational attainment in the general population

por Ganna, Andrea, Genovese, Giulio, Howrigan, Daniel P., Byrnes, Andrea, Kurki, Mitja, Zekavat, Seyedeh M., Whelan, Christopher W., Kals, Mart, Nivard, Michel G., Bloemendal, Alex, Bloom, Jonathan M., Goldstein, Jacqueline I., Poterba, Timothy, Seed, Cotton, Handsaker, Robert E., Natarajan, Pradeep, Mägi, Reedik, Gage, Diane, Robinson, Elise B., Metspalu, Andres, Salomaa, Veikko, Suvisaari, Jaana, Purcell, Shaun M., Sklar, Pamela, Kathiresan, Sekar, Daly, Mark J., McCarroll, Steven A., Sullivan, Patrick F., Palotie, Aarno, Esko, Tõnu, Hultman, Christina, Neale, Benjamin M.
Publicado 2016

Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer

por Zekavat, Seyedeh M., Lin, Shu-Hong, Bick, Alexander G., Liu, Aoxing, Paruchuri, Kaavya, Uddin, Md Mesbah, Ye, Yixuan, Yu, Zhaolong, Liu, Xiaoxi, Kamatani, Yoichiro, Pirruccello, James P., Pampana, Akhil, Loh, Po-Ru, Kohli, Puja, McCarroll, Steven A., Neale, Benjamin, Engels, Eric A., Brown, Derek W., Smoller, Jordan W., Green, Robert, Karlson, Elizabeth W., Lebo, Matthew, Ellinor, Patrick T., Weiss, Scott T., Daly, Mark J., Terao, Chikashi, Zhao, Hongyu, Ebert, Benjamin L., Ganna, Andrea, Machiela, Mitchell J., Genovese, Giulio, Natarajan, Pradeep
Publicado 2020

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

por Zekavat, Seyedeh M., Ruotsalainen, Sanni, Handsaker, Robert E., Alver, Maris, Bloom, Jonathan, Poterba, Timothy, Seed, Cotton, Ernst, Jason, Chaffin, Mark, Engreitz, Jesse, Peloso, Gina M., Manichaikul, Ani, Yang, Chaojie, Ryan, Kathleen A., Fu, Mao, Johnson, W. Craig, Tsai, Michael, Budoff, Matthew, Vasan, Ramachandran S., Cupples, L. Adrienne, Rotter, Jerome I., Rich, Stephen S., Post, Wendy, Mitchell, Braxton D., Correa, Adolfo, Metspalu, Andres, Wilson, James G., Salomaa, Veikko, Kellis, Manolis, Daly, Mark J., Neale, Benjamin M., McCarroll, Steven, Surakka, Ida, Esko, Tonu, Ganna, Andrea, Ripatti, Samuli, Kathiresan, Sekar, Natarajan, Pradeep
Publicado 2018

Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

por Zekavat, Seyedeh M., Ruotsalainen, Sanni, Handsaker, Robert E., Alver, Maris, Bloom, Jonathan, Poterba, Timothy, Seed, Cotton, Ernst, Jason, Chaffin, Mark, Engreitz, Jesse, Peloso, Gina M., Manichaikul, Ani, Yang, Chaojie, Ryan, Kathleen A., Fu, Mao, Johnson, W. Craig, Tsai, Michael, Budoff, Matthew, Vasan, Ramachandran S., Cupples, L. Adrienne, Rotter, Jerome I., Rich, Stephen S., Post, Wendy, Mitchell, Braxton D., Correa, Adolfo, Metspalu, Andres, Wilson, James G., Salomaa, Veikko, Kellis, Manolis, Daly, Mark J., Neale, Benjamin M., McCarroll, Steven, Surakka, Ida, Esko, Tonu, Ganna, Andrea, Ripatti, Samuli, Kathiresan, Sekar, Natarajan, Pradeep
Publicado 2018

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

por Natarajan, Pradeep, Peloso, Gina M., Zekavat, Seyedeh Maryam, Montasser, May, Ganna, Andrea, Chaffin, Mark, Khera, Amit V., Zhou, Wei, Bloom, Jonathan M., Engreitz, Jesse M., Ernst, Jason, O’Connell, Jeffrey R., Ruotsalainen, Sanni E., Alver, Maris, Manichaikul, Ani, Johnson, W. Craig, Perry, James A., Poterba, Timothy, Seed, Cotton, Surakka, Ida L., Esko, Tonu, Ripatti, Samuli, Salomaa, Veikko, Correa, Adolfo, Vasan, Ramachandran S., Kellis, Manolis, Neale, Benjamin M., Lander, Eric S., Abecasis, Goncalo, Mitchell, Braxton, Rich, Stephen S., Wilson, James G., Cupples, L. Adrienne, Rotter, Jerome I., Willer, Cristen J., Kathiresan, Sekar
Publicado 2018

Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

por Zekavat, Seyedeh M., Ruotsalainen, Sanni, Handsaker, Robert E., Alver, Maris, Bloom, Jonathan, Poterba, Timothy, Seed, Cotton, Ernst, Jason, Chaffin, Mark, Engreitz, Jesse, Peloso, Gina M., Manichaikul, Ani, Yang, Chaojie, Ryan, Kathleen A., Fu, Mao, Johnson, W. Craig, Tsai, Michael, Budoff, Matthew, Vasan, Ramachandran S., Cupples, L. Adrienne, Rotter, Jerome I., Rich, Stephen S., Post, Wendy, Mitchell, Braxton D., Correa, Adolfo, Metspalu, Andres, Wilson, James G., Salomaa, Veikko, Kellis, Manolis, Daly, Mark J., Neale, Benjamin M., McCarroll, Steven, Surakka, Ida, Esko, Tonu, Ganna, Andrea, Ripatti, Samuli, Kathiresan, Sekar, Natarajan, Pradeep
Publicado 2020

A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program

por Verma, Anurag, Tsao, Noah L., Thomann, Lauren O., Ho, Yuk-Lam, Iyengar, Sudha K., Luoh, Shiuh-Wen, Carr, Rotonya, Crawford, Dana C., Efird, Jimmy T., Huffman, Jennifer E., Hung, Adriana, Ivey, Kerry L., Levin, Michael G., Lynch, Julie, Natarajan, Pradeep, Pyarajan, Saiju, Bick, Alexander G., Costa, Lauren, Genovese, Giulio, Hauger, Richard, Madduri, Ravi, Pathak, Gita A., Polimanti, Renato, Voight, Benjamin, Vujkovic, Marijana, Zekavat, Seyedeh Maryam, Zhao, Hongyu, Ritchie, Marylyn D., Chang, Kyong-Mi, Cho, Kelly, Casas, Juan P., Tsao, Philip S., Gaziano, J. Michael, O’Donnell, Christopher, Damrauer, Scott M., Liao, Katherine P.
Publicado 2022

Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease

por Emdin, Connor A., Khera, Amit V., Chaffin, Mark, Klarin, Derek, Natarajan, Pradeep, Aragam, Krishna, Haas, Mary, Bick, Alexander, Zekavat, Seyedeh M., Nomura, Akihiro, Ardissino, Diego, Wilson, James G., Schunkert, Heribert, McPherson, Ruth, Watkins, Hugh, Elosua, Roberto, Bown, Matthew J., Samani, Nilesh J., Baber, Usman, Erdmann, Jeanette, Gupta, Namrata, Danesh, John, Chasman, Daniel, Ridker, Paul, Denny, Joshua, Bastarache, Lisa, Lichtman, Judith H., D’Onofrio, Gail, Mattera, Jennifer, Spertus, John A., Sheu, Wayne H.-H., Taylor, Kent D., Psaty, Bruce M., Rich, Stephen S., Post, Wendy, Rotter, Jerome I., Chen, Yii-Der Ida, Krumholz, Harlan, Saleheen, Danish, Gabriel, Stacey, Kathiresan, Sekar
Publicado 2018