Thermophilic Adaptation in Prokaryotes Is Constrained by Metabolic Costs of Proteostasis

por Venev, Sergey V, Zeldovich, Konstantin B
Publicado 2018

Protein and DNA Sequence Determinants of Thermophilic Adaptation

por Zeldovich, Konstantin B, Berezovsky, Igor N, Shakhnovich, Eugene I
Publicado 2007

Positive and Negative Design in Stability and Thermal Adaptation of Natural Proteins

por Berezovsky, Igor N, Zeldovich, Konstantin B, Shakhnovich, Eugene I
Publicado 2007

An allosteric pathway explains beneficial fitness in yeast for long‐range mutations in an essential TIM barrel enzyme

por Chan, Yvonne H., Zeldovich, Konstantin B., Matthews, Charles R.
Publicado 2020

A First-Principles Model of Early Evolution: Emergence of Gene Families, Species, and Preferred Protein Folds

por Zeldovich, Konstantin B, Chen, Peiqiu, Shakhnovich, Boris E, Shakhnovich, Eugene I
Publicado 2007

Correlation of fitness landscapes from three orthologous TIM barrels originates from sequence and structure constraints

por Chan, Yvonne H., Venev, Sergey V., Zeldovich, Konstantin B., Matthews, C. Robert
Publicado 2017

Latent Effects of Hsp90 Mutants Revealed at Reduced Expression Levels

por Jiang, Li, Mishra, Parul, Hietpas, Ryan T., Zeldovich, Konstantin B., Bolon, Daniel N. A.
Publicado 2013

The Adaptive Potential of the Middle Domain of Yeast Hsp90

por Cote-Hammarlof, Pamela A, Fragata, Inês, Flynn, Julia, Mavor, David, Zeldovich, Konstantin B, Bank, Claudia, Bolon, Daniel N A
Publicado 2020

Influenza Virus Drug Resistance: A Time-Sampled Population Genetics Perspective

por Foll, Matthieu, Poh, Yu-Ping, Renzette, Nicholas, Ferrer-Admetlla, Anna, Bank, Claudia, Shim, Hyunjin, Malaspinas, Anna-Sapfo, Ewing, Gregory, Liu, Ping, Wegmann, Daniel, Caffrey, Daniel R., Zeldovich, Konstantin B., Bolon, Daniel N., Wang, Jennifer P., Kowalik, Timothy F., Schiffer, Celia A., Finberg, Robert W., Jensen, Jeffrey D.
Publicado 2014