Discovery of Novel Inhibitor for WNT/β-Catenin Pathway by Tankyrase 1/2 Structure-Based Virtual Screening

por Li, Bo, Liang, Jinxia, Lu, Feng, Zeng, Guandi, Zhang, Jindao, Ma, Yinxing, Liu, Peng, Wang, Qin, Zhou, Qian, Chen, Liang
Publicado 2020

Genome Recombination-Mediated tRNA Up-Regulation Conducts General Antibiotic Resistance of Bacteria at Early Stage

por Fang, Huiying, Zeng, Guandi, Gu, Wei, Wang, Yubin, Zhao, Jing, Zheng, Tingkai, Xu, Lina, Liu, Yutong, Zhang, Jinning, Sun, Xuesong, Zhang, Gong
Publicado 2022

In vivo genome-wide CRISPR screening identifies ZNF24 as a negative NF-κB modulator in lung cancer

por Liu, Lu, Lei, Yuxi, Chen, Wensheng, Zhou, Qian, Zheng, Zongyao, Zeng, Guandi, Liu, Wanting, Feng, Pengju, Zhang, Zhiyi, Yu, Lei, Chen, Liang
Publicado 2022

GATA6 Exerts Potent Lung Cancer Suppressive Function by Inducing Cell Senescence

por Chen, Wensheng, Chen, Zhipeng, Zhang, Miaomiao, Tian, Yahui, Liu, Lu, Lan, Ruirui, Zeng, Guandi, Fu, Xiaolong, Ru, Guoqing, Liu, Wanting, Chen, Liang, Fan, Zhenzhen
Publicado 2020

Inactivation of tumor suppressor gene Clusterin leads to hyperactivation of TAK1-NF-κB signaling axis in lung cancer cells and denotes a therapeutic opportunity

por Chen, Zhipeng, Fan, Zhenzhen, Dou, Xiaowei, Zhou, Qian, Zeng, Guandi, Liu, Lu, Chen, Wensheng, Lan, Ruirui, Liu, Wanting, Ru, Guoqing, Yu, Lei, He, Qing-Yu, Chen, Liang
Publicado 2020

A tumor suppressor enhancing module orchestrated by GATA4 denotes a therapeutic opportunity for GATA4 deficient HCC patients

por Lu, Feng, Zhou, Qian, Liu, Lu, Zeng, Guandi, Ci, Weimin, Liu, Wanting, Zhang, Gong, Zhang, Zhiyi, Wang, Peng, Zhang, Aiqun, Gao, Yunfei, Yu, Lei, He, Qingyu, Chen, Liang
Publicado 2020

Targeting hyperactive TGFBR2 for treating MYOCD deficient lung cancer

por Zhou, Qian, Chen, Wensheng, Fan, Zhenzhen, Chen, Zhipeng, Liang, Jinxia, Zeng, Guandi, Liu, Lu, Liu, Wanting, Yang, Tong, Cao, Xin, Yu, Biao, Xu, Meng, Chen, Ye-Guang, Chen, Liang
Publicado 2021

Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition

por Gao, Lei, Hu, Yong, Tian, Yahui, Fan, Zhenzhen, Wang, Kun, Li, Hongdan, Zhou, Qian, Zeng, Guandi, Hu, Xin, Yu, Lei, Zhou, Shiyu, Tong, Xinyuan, Huang, Hsinyi, Chen, Haiquan, Liu, Qingsong, Liu, Wanting, Zhang, Gong, Zeng, Musheng, Zhou, Guangbiao, He, Qingyu, Ji, Hongbin, Chen, Liang
Publicado 2019