A novel variant in GLIS3 is associated with osteoarthritis

por Casalone, Elisabetta, Tachmazidou, Ioanna, Zengini, Eleni, Hatzikotoulas, Konstantinos, Hackinger, Sophie, Suveges, Daniel, Steinberg, Julia, Rayner, Nigel William, Wilkinson, Jeremy Mark, Panoutsopoulou, Kalliope, Zeggini, Eleftheria
Publicado 2018

Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis

por Steinberg, Julia, Brooks, Roger A, Southam, Lorraine, Bhatnagar, Sahir, Roumeliotis, Theodoros I, Hatzikotoulas, Konstantinos, Zengini, Eleni, Wilkinson, J Mark, Choudhary, Jyoti S, McCaskie, Andrew W, Zeggini, Eleftheria
Publicado 2018

A Dietary Pattern with High Sugar Content Is Associated with Cardiometabolic Risk Factors in the Pomak Population

por Farmaki, Aliki-Eleni, Rayner, Nigel W, Kafyra, Maria, Matchan, Angela, Ntaoutidou, Kyriaki, Feritoglou, Pournar, Athanasiadis, Antonis, Gilly, Arthur, Mamakou, Vasiliki, Zengini, Eleni, Karaleftheri, Maria, Zeggini, Eleftheria, Dedoussis, George
Publicado 2019

Evidence for genetic contribution to the increased risk of type 2 diabetes in schizophrenia

por Hackinger, Sophie, Prins, Bram, Mamakou, Vasiliki, Zengini, Eleni, Marouli, Eirini, Brčić, Luka, Serafetinidis, Ioannis, Lamnissou, Klea, Kontaxakis, Vassilis, Dedoussis, George, Gonidakis, Fragiskos, Thanopoulou, Anastasia, Tentolouris, Nikolaos, Tsezou, Aspasia, Zeggini, Eleftheria
Publicado 2018

Radiographic endophenotyping in hip osteoarthritis improves the precision of genetic association analysis

por Panoutsopoulou, Kalliope, Thiagarajah, Shankar, Zengini, Eleni, Day-Williams, Aaron G, Ramos, Yolande FM, Meessen, Jennifer MTA, Huetink, Kasper, Nelissen, Rob GHH, Southam, Lorraine, Rayner, N William, Doherty, Michael, Meulenbelt, Ingrid, Zeggini, Eleftheria, Wilkinson, J Mark
Publicado 2017

Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5

por Hatzikotoulas, Konstantinos, Roposch, Andreas, Shah, Karan M., Clark, Matthew J., Bratherton, Selina, Limbani, Vasanti, Steinberg, Julia, Zengini, Eleni, Warsame, Kaltuun, Ratnayake, Madhushika, Tselepi, Maria, Schwartzentruber, Jeremy, Loughlin, John, Eastwood, Deborah M., Zeggini, Eleftheria, Wilkinson, J. Mark
Publicado 2018

Evaluating the glucose raising effect of established loci via a genetic risk score

por Marouli, Eirini, Kanoni, Stavroula, Mamakou, Vasiliki, Hackinger, Sophie, Southam, Lorraine, Prins, Bram, Rentari, Angela, Dimitriou, Maria, Zengini, Eleni, Gonidakis, Fragiskos, Kolovou, Genovefa, Kontaxakis, Vassilis, Rallidis, Loukianos, Tentolouris, Nikolaos, Thanopoulou, Anastasia, Lamnissou, Klea, Dedoussis, George, Zeggini, Eleftheria, Deloukas, Panagiotis
Publicado 2017

Combination therapy as a potential risk factor for the development of type 2 diabetes in patients with schizophrenia: the GOMAP study

por Mamakou, Vasiliki, Hackinger, Sophie, Zengini, Eleni, Tsompanaki, Evgenia, Marouli, Eirini, Serafetinidis, Ioannis, Prins, Bram, Karabela, Athina, Glezou, Eirini, Southam, Lorraine, Rayner, Nigel W., Kuchenbaecker, Karoline, Lamnissou, Klea, Kontaxakis, Vassilis, Dedoussis, George, Gonidakis, Fragiskos, Thanopoulou, Anastasia, Tentolouris, Nikolaos, Zeggini, Eleftheria
Publicado 2018

Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus

por Hackinger, Sophie, Trajanoska, Katerina, Styrkarsdottir, Unnur, Zengini, Eleni, Steinberg, Julia, Ritchie, Graham R.S., Hatzikotoulas, Konstantinos, Gilly, Arthur, Evangelou, Evangelos, Kemp, John P., Evans, David, Ingvarsson, Thorvaldur, Jonsson, Helgi, Thorsteinsdottir, Unnur, Stefansson, Kari, McCaskie, Andrew W., Brooks, Roger A., Wilkinson, Jeremy M., Rivadeneira, Fernando, Zeggini, Eleftheria
Publicado 2017

Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank

por Tachmazidou, Ioanna, Hatzikotoulas, Konstantinos, Southam, Lorraine, Esparza-Gordillo, Jorge, Haberland, Valeriia, Zheng, Jie, Johnson, Toby, Koprulu, Mine, Zengini, Eleni, Steinberg, Julia, Wilkinson, Jeremy M, Bhatnagar, Sahir, Hoffman, Joshua D, Buchan, Natalie, Süveges, Dániel, Yerges-Armstrong, Laura, Smith, George Davey, Gaunt, Tom R, Scott, Robert A, McCarthy, Linda C, Zeggini, Eleftheria
Publicado 2019

Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis

por Zengini, Eleni, Hatzikotoulas, Konstantinos, Tachmazidou, Ioanna, Steinberg, Julia, Hartwig, Fernando P., Southam, Lorraine, Hackinger, Sophie, Boer, Cindy G., Styrkarsdottir, Unnur, Gilly, Arthur, Suveges, Daniel, Killian, Britt, Ingvarsson, Thorvaldur, Jonsson, Helgi, Babis, George C., McCaskie, Andrew, Uitterlinden, Andre G., van Meurs, Joyce B. J., Thorsteinsdottir, Unnur, Stefansson, Kari, Smith, George Davey, Wilkinson, Jeremy M., Zeggini, Eleftheria
Publicado 2018

Genetic characterization of Greek population isolates reveals strong genetic drift at missense and trait-associated variants

por Panoutsopoulou, Kalliope, Hatzikotoulas, Konstantinos, Xifara, Dionysia Kiara, Colonna, Vincenza, Farmaki, Aliki-Eleni, Ritchie, Graham R. S., Southam, Lorraine, Gilly, Arthur, Tachmazidou, Ioanna, Fatumo, Segun, Matchan, Angela, Rayner, Nigel W., Ntalla, Ioanna, Mezzavilla, Massimo, Chen, Yuan, Kiagiadaki, Chrysoula, Zengini, Eleni, Mamakou, Vasiliki, Athanasiadis, Antonis, Giannakopoulou, Margarita, Kariakli, Vassiliki-Eirini, Nsubuga, Rebecca N., Karabarinde, Alex, Sandhu, Manjinder, McVean, Gil, Tyler-Smith, Chris, Tsafantakis, Emmanouil, Karaleftheri, Maria, Xue, Yali, Dedoussis, George, Zeggini, Eleftheria
Publicado 2014

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

por Boer, Cindy G., Hatzikotoulas, Konstantinos, Southam, Lorraine, Stefánsdóttir, Lilja, Zhang, Yanfei, Coutinho de Almeida, Rodrigo, Wu, Tian T., Zheng, Jie, Hartley, April, Teder-Laving, Maris, Skogholt, Anne Heidi, Terao, Chikashi, Zengini, Eleni, Alexiadis, George, Barysenka, Andrei, Bjornsdottir, Gyda, Gabrielsen, Maiken E., Gilly, Arthur, Ingvarsson, Thorvaldur, Johnsen, Marianne B., Jonsson, Helgi, Kloppenburg, Margreet, Luetge, Almut, Lund, Sigrun H., Mägi, Reedik, Mangino, Massimo, Nelissen, Rob R.G.H.H., Shivakumar, Manu, Steinberg, Julia, Takuwa, Hiroshi, Thomas, Laurent F., Tuerlings, Margo, Babis, George C., Cheung, Jason Pui Yin, Kang, Jae Hee, Kraft, Peter, Lietman, Steven A., Samartzis, Dino, Slagboom, P. Eline, Stefansson, Kari, Thorsteinsdottir, Unnur, Tobias, Jonathan H., Uitterlinden, André G., Winsvold, Bendik, Zwart, John-Anker, Davey Smith, George, Sham, Pak Chung, Thorleifsson, Gudmar, Gaunt, Tom R., Morris, Andrew P., Valdes, Ana M., Tsezou, Aspasia, Cheah, Kathryn S.E., Ikegawa, Shiro, Hveem, Kristian, Esko, Tõnu, Wilkinson, J. Mark, Meulenbelt, Ingrid, Lee, Ming Ta Michael, van Meurs, Joyce B.J., Styrkársdóttir, Unnur, Zeggini, Eleftheria
Publicado 2021

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

por Boer, Cindy G., Hatzikotoulas, Konstantinos, Southam, Lorraine, Stefánsdóttir, Lilja, Zhang, Yanfei, Coutinho de Almeida, Rodrigo, Wu, Tian T., Zheng, Jie, Hartley, April, Teder-Laving, Maris, Skogholt, Anne Heidi, Terao, Chikashi, Zengini, Eleni, Alexiadis, George, Barysenka, Andrei, Bjornsdottir, Gyda, Gabrielsen, Maiken E., Gilly, Arthur, Ingvarsson, Thorvaldur, Johnsen, Marianne B., Jonsson, Helgi, Kloppenburg, Margreet, Luetge, Almut, Lund, Sigrun H., Mägi, Reedik, Mangino, Massimo, Nelissen, Rob R.G.H.H., Shivakumar, Manu, Steinberg, Julia, Takuwa, Hiroshi, Thomas, Laurent F., Tuerlings, Margo, Babis, George C., Yin Cheung, Jason Pui, Kang, Jae Hee, Kraft, Peter, Lietman, Steven A., Samartzis, Dino, Slagboom, P. Eline, Stefansson, Kari, Thorsteinsdottir, Unnur, Tobias, Jonathan H., Uitterlinden, André G., Winsvold, Bendik, Zwart, John-Anker, Smith, George Davey, Sham, Pak Chung, Thorleifsson, Gudmar, Gaunt, Tom R., Morris, Andrew P., Valdes, Ana M., Tsezou, Aspasia, Cheah, Kathryn S.E., Ikegawa, Shiro, Hveem, Kristian, Esko, Tõnu, Wilkinson, J. Mark, Meulenbelt, Ingrid, Michael Lee, Ming Ta, van Meurs, Joyce B.J., Styrkársdóttir, Unnur, Zeggini, Eleftheria
Publicado 2021

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

por Wessel, Jennifer, Chu, Audrey Y, Willems, Sara M, Wang, Shuai, Yaghootkar, Hanieh, Brody, Jennifer A, Dauriz, Marco, Hivert, Marie-France, Raghavan, Sridharan, Lipovich, Leonard, Hidalgo, Bertha, Fox, Keolu, Huffman, Jennifer E, An, Ping, Lu, Yingchang, Rasmussen-Torvik, Laura J, Grarup, Niels, Ehm, Margaret G, Li, Li, Baldridge, Abigail S, Stančáková, Alena, Abrol, Ravinder, Besse, Céline, Boland, Anne, Bork-Jensen, Jette, Fornage, Myriam, Freitag, Daniel F, Garcia, Melissa E, Guo, Xiuqing, Hara, Kazuo, Isaacs, Aaron, Jakobsdottir, Johanna, Lange, Leslie A, Layton, Jill C, Li, Man, Hua Zhao, Jing, Meidtner, Karina, Morrison, Alanna C, Nalls, Mike A, Peters, Marjolein J, Sabater-Lleal, Maria, Schurmann, Claudia, Silveira, Angela, Smith, Albert V, Southam, Lorraine, Stoiber, Marcus H, Strawbridge, Rona J, Taylor, Kent D, Varga, Tibor V, Allin, Kristine H, Amin, Najaf, Aponte, Jennifer L, Aung, Tin, Barbieri, Caterina, Bihlmeyer, Nathan A, Boehnke, Michael, Bombieri, Cristina, Bowden, Donald W, Burns, Sean M, Chen, Yuning, Chen, Yii-DerI, Cheng, Ching-Yu, Correa, Adolfo, Czajkowski, Jacek, Dehghan, Abbas, Ehret, Georg B, Eiriksdottir, Gudny, Escher, Stefan A, Farmaki, Aliki-Eleni, Frånberg, Mattias, Gambaro, Giovanni, Giulianini, Franco, Goddard, William A, Goel, Anuj, Gottesman, Omri, Grove, Megan L, Gustafsson, Stefan, Hai, Yang, Hallmans, Göran, Heo, Jiyoung, Hoffmann, Per, Ikram, Mohammad K, Jensen, Richard A, Jørgensen, Marit E, Jørgensen, Torben, Karaleftheri, Maria, Khor, Chiea C, Kirkpatrick, Andrea, Kraja, Aldi T, Kuusisto, Johanna, Lange, Ethan M, Lee, I T, Lee, Wen-Jane, Leong, Aaron, Liao, Jiemin, Liu, Chunyu, Liu, Yongmei, Lindgren, Cecilia M, Linneberg, Allan, Malerba, Giovanni, Mamakou, Vasiliki, Marouli, Eirini, Maruthur, Nisa M, Matchan, Angela, McKean-Cowdin, Roberta, McLeod, Olga, Metcalf, Ginger A, Mohlke, Karen L, Muzny, Donna M, Ntalla, Ioanna, Palmer, Nicholette D, Pasko, Dorota, Peter, Andreas, Rayner, Nigel W, Renström, Frida, Rice, Ken, Sala, Cinzia F, Sennblad, Bengt, Serafetinidis, Ioannis, Smith, Jennifer A, Soranzo, Nicole, Speliotes, Elizabeth K, Stahl, Eli A, Stirrups, Kathleen, Tentolouris, Nikos, Thanopoulou, Anastasia, Torres, Mina, Traglia, Michela, Tsafantakis, Emmanouil, Javad, Sundas, Yanek, Lisa R, Zengini, Eleni, Becker, Diane M, Bis, Joshua C, Brown, James B, Adrienne Cupples, L, Hansen, Torben, Ingelsson, Erik, Karter, Andrew J, Lorenzo, Carlos, Mathias, Rasika A, Norris, Jill M, Peloso, Gina M, Sheu, Wayne H.-H., Toniolo, Daniela, Vaidya, Dhananjay, Varma, Rohit, Wagenknecht, Lynne E, Boeing, Heiner, Bottinger, Erwin P, Dedoussis, George, Deloukas, Panos, Ferrannini, Ele, Franco, Oscar H, Franks, Paul W, Gibbs, Richard A, Gudnason, Vilmundur, Hamsten, Anders, Harris, Tamara B, Hattersley, Andrew T, Hayward, Caroline, Hofman, Albert, Jansson, Jan-Håkan, Langenberg, Claudia, Launer, Lenore J, Levy, Daniel, Oostra, Ben A, O'Donnell, Christopher J, O'Rahilly, Stephen, Padmanabhan, Sandosh, Pankow, James S, Polasek, Ozren, Province, Michael A, Rich, Stephen S, Ridker, Paul M, Rudan, Igor, Schulze, Matthias B, Smith, Blair H, Uitterlinden, André G, Walker, Mark, Watkins, Hugh, Wong, Tien Y, Zeggini, Eleftheria, Laakso, Markku, Borecki, Ingrid B, Chasman, Daniel I, Pedersen, Oluf, Psaty, Bruce M, Shyong Tai, E, van Duijn, Cornelia M, Wareham, Nicholas J, Waterworth, Dawn M, Boerwinkle, Eric, Linda Kao, W H, Florez, Jose C, Loos, Ruth J.F., Wilson, James G, Frayling, Timothy M, Siscovick, David S, Dupuis, Josée, Rotter, Jerome I, Meigs, James B, Scott, Robert A, Goodarzi, Mark O
Publicado 2015