Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation

por Harischandra, Dilshan S., Ghaisas, Shivani, Zenitsky, Gary, Jin, Huajun, Kanthasamy, Arthi, Anantharam, Vellareddy, Kanthasamy, Anumantha G.
Publicado 2019

Mechanistic Insights Into Gut Microbiome Dysbiosis-Mediated Neuroimmune Dysregulation and Protein Misfolding and Clearance in the Pathogenesis of Chronic Neurodegenerative Disorder...

por Padhi, Piyush, Worth, Carter, Zenitsky, Gary, Jin, Huajun, Sambamurti, Kumar, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G.
Publicado 2022

Impact of Environmental Risk Factors on Mitochondrial Dysfunction, Neuroinflammation, Protein Misfolding, and Oxidative Stress in the Etiopathogenesis of Parkinson’s Disease

por Huang, Minhong, Bargues-Carot, Alejandra, Riaz, Zainab, Wickham, Hannah, Zenitsky, Gary, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Arthi, Kanthasamy, Anumantha G.
Publicado 2022

Mitochondrial dysfunction–induced H3K27 hyperacetylation perturbs enhancers in Parkinson’s disease

por Huang, Minhong, Lou, Dan, Charli, Adhithiya, Kong, Dehui, Jin, Huajun, Zenitsky, Gary, Anantharam, Vellareddy, Kanthasamy, Arthi, Wang, Zhibin, Kanthasamy, Anumantha G.
Publicado 2021

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis (TWEAK) Enhances Activation of STAT3/NLRC4 Inflammasome Signaling Axis through PKCδ in Astrocytes: Implications for Parkinson’s...

por Samidurai, Manikandan, Tarale, Prashant, Janarthanam, Chelva, Estrada, Crystal Gomez, Gordon, Richard, Zenitsky, Gary, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Anumantha G., Kanthasamy, Arthi
Publicado 2020

PKC Delta Activation Promotes Endoplasmic Reticulum Stress (ERS) and NLR Family Pyrin Domain-Containing 3 (NLRP3) Inflammasome Activation Subsequent to Asynuclein-Induced Microglia...

por Samidurai, Manikandan, Palanisamy, Bharathi N., Bargues-Carot, Alejandra, Hepker, Monica, Kondru, Naveen, Manne, Sireesha, Zenitsky, Gary, Jin, Huajun, Anantharam, Vellareddy, Kanthasamy, Anumantha G., Kanthasamy, Arthi
Publicado 2021

Chronic Manganese Exposure and the Enteric Nervous System: An in Vitro and Mouse in Vivo Study

por Ghaisas, Shivani, Harischandra, Dilshan S., Palanisamy, Bharathi, Proctor, Alexandra, Jin, Huajun, Dutta, Somak, Sarkar, Souvarish, Langley, Monica, Zenitsky, Gary, Anantharam, Vellareddy, Kanthasamy, Arthi, Phillips, Gregory J., Kanthasamy, Anumantha
Publicado 2021