GOALs in relapsed DLBCL

por Rösler, Wiebke, Zenz, Thorsten
Publicado 2022

Energy metabolism is co-determined by genetic variants in chronic lymphocytic leukemia and influences drug sensitivity

por Lu, Junyan, Böttcher, Martin, Walther, Tatjana, Mougiakakos, Dimitrios, Zenz, Thorsten, Huber, Wolfgang
Publicado 2019

Inferring tumor-specific cancer dependencies through integrating ex vivo drug response assays and drug-protein profiling

por Batzilla, Alina, Lu, Junyan, Kivioja, Jarno, Putzker, Kerstin, Lewis, Joe, Zenz, Thorsten, Huber, Wolfgang
Publicado 2022

Multi‐Omics Factor Analysis—a framework for unsupervised integration of multi‐omics data sets

por Argelaguet, Ricard, Velten, Britta, Arnol, Damien, Dietrich, Sascha, Zenz, Thorsten, Marioni, John C, Buettner, Florian, Huber, Wolfgang, Stegle, Oliver
Publicado 2018

Inhibitors of Bcl-2 and Bruton’s tyrosine kinase synergize to abrogate diffuse large B-cell lymphoma growth in vitro and in orthotopic xenotransplantation models

por Bertram, Katrin, Leary, Peter John, Boudesco, Christophe, Fullin, Jonas, Stirm, Kristin, Dalal, Vineet, Zenz, Thorsten, Tzankov, Alexandar, Müller, Anne
Publicado 2021

BRAF inhibitor treatment of classical hairy cell leukemia allows successful vaccination against SARS-CoV-2

por Konrat, Judith, Rösler, Wiebke, Roiss, Michael, Meier-Abt, Fabienne, Widmer, Corinne C., Balabanov, Stefan, Manz, Markus G., Zenz, Thorsten
Publicado 2022

Subgroup-specific gene expression profiles and mixed epistasis in chronic lymphocytic leukemia

por Lütge, Almut, Lu, Junyan, Hüllein, Jennifer, Walther, Tatjana, Sellner, Leopold, Wu, Bian, Rosenquist, Richard, Oakes, Christopher C., Dietrich, Sascha, Huber, Wolfgang, Zenz, Thorsten
Publicado 2023

Pathological RANK signaling in B cells drives autoimmunity and chronic lymphocytic leukemia

por Alankus, Begüm, Ecker, Veronika, Vahl, Nathalie, Braun, Martina, Weichert, Wilko, Macher-Göppinger, Stephan, Gehring, Torben, Neumayer, Tanja, Zenz, Thorsten, Buchner, Maike, Ruland, Jürgen
Publicado 2020

Tumor cell-derived IL-10 promotes cell-autonomous growth and immune escape in diffuse large B-cell lymphoma

por Stirm, Kristin, Leary, Peter, Bertram, Katrin, Núñez, Nicolás Gonzalo, Wüst, Daria, Boudesco, Christophe, Verhoeyen, Els, Zenz, Thorsten, Becher, Burkhard, Menter, Thomas, Tzankov, Alexandar, Müller, Anne
Publicado 2021

Clonal evolution in chronic lymphocytic leukemia is scant in relapsed but accelerated in refractory cases after chemo(immune) therapy

por Zapatka, Marc, Tausch, Eugen, Öztürk, Selcen, Yosifov, Deyan Yordanov, Seiffert, Martina, Zenz, Thorsten, Schneider, Christof, Bloehdorn, Johannes, Döhner, Hartmut, Mertens, Daniel, Lichter, Peter, Stilgenbauer, Stephan
Publicado 2021

S257: CAR T CELLS AND THEIR IMMUNE ENVIRONMENT SHAPE DISTINCT IMMUNE PROFILES IN RESPONSE AND TOXICITY IN B CELL LYMPHOMA PATIENTS

por Kreutmair, Stefanie, Schaefer, Maximilian, Stolz, Sebastian, Merten, Carla, Ulutekin, Can, Wertheimer, Tobias, Ingelfinger, Florian, Unger, Susanne, Alberti, Chiara, Sethi, Aakriti, Manz, Markus, Zenz, Thorsten, Müller, Antonia, Widmer, Corinne, Becher, Burkhard
Publicado 2023

CAR T-cell Infusion Following Checkpoint Inhibition Can Induce Remission in Chemorefractory Post-transplant Lymphoproliferative Disorder of the CNS

por Rösler, Wiebke, Bink, Andrea, Bissig, Marina, Imbach, Lukas, Marques Maggio, Ewerton, Manz, Markus G., Müller, Thomas, Roth, Patrick, Rushing, Elisabeth, Widmer, Corinne, Zenz, Thorsten, von Moos, Seraina, Müller, Antonia M. S.
Publicado 2022

SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia

por Johansson, Patricia, Klein-Hitpass, Ludger, Choidas, Axel, Habenberger, Peter, Mahboubi, Bijan, Kim, Baek, Bergmann, Anke, Scholtysik, René, Brauser, Martina, Lollies, Anna, Siebert, Reiner, Zenz, Thorsten, Dührsen, Ulrich, Küppers, Ralf, Dürig, Jan
Publicado 2018

Control of PD-L1 expression in CLL-cells by stromal triggering of the Notch-c-Myc-EZH2 oncogenic signaling axis

por Böttcher, Martin, Bruns, Heiko, Völkl, Simon, Lu, Junyan, Chartomatsidou, Elisavet, Papakonstantinou, Nikos, Mentz, Kristin, Büttner-Herold, Maike, Zenz, Thorsten, Herling, Marco, Huber, Wolfgang, Ghia, Paolo, Stamatopoulos, Kostas, Mackensen, Andreas, Mougiakakos, Dimitrios
Publicado 2021

P600: DNA METHYLATION ANALYSIS OF B-CELL PROLYMPHOCYTIC LEUKEMIA REVEALS TWO EPIGENETIC SUBTYPES WITH DISTINCT BIOLOGICAL AND CLINICAL FEATURES

por Charalampopoulou, Stella, Chapiro, Elise, Nadeu, Ferran, Zenz, Thorsten, Beà, Silvia, Roos-Weil, Damien, Bernard, Olivier, Susin, Santos A, Matutes, Estella, Campo, Elias, Duran-Ferrer, Martí, Nguyen-Khac, Florence, Ignacio Martín-Subero, José
Publicado 2023

Comparing the value of mono- vs coculture for high-throughput compound screening in hematological malignancies

por Herbst, Sophie A., Kim, Vladislav, Roider, Tobias, Schitter, Eva C., Bruch, Peter-Martin, Liebers, Nora, Kolb, Carolin, Knoll, Mareike, Lu, Junyan, Dreger, Peter, Müller-Tidow, Carsten, Zenz, Thorsten, Huber, Wolfgang, Dietrich, Sascha
Publicado 2023

Survey of ex vivo drug combination effects in chronic lymphocytic leukemia reveals synergistic drug effects and genetic dependencies

por Lukas, Marina, Velten, Britta, Sellner, Leopold, Tomska, Katarzyna, Hüellein, Jennifer, Walther, Tatjana, Wagner, Lena, Muley, Carolin, Wu, Bian, Oleś, Małgorzata, Dietrich, Sascha, Jethwa, Alexander, Bohnenberger, Hanibal, Lu, Junyan, Huber, Wolfgang, Zenz, Thorsten
Publicado 2020

A gene expression assay based on chronic lymphocytic leukemia activation in the microenvironment to predict progression

por Abrisqueta, Pau, Medina, Daniel, Villacampa, Guillermo, Lu, Junyan, Alcoceba, Miguel, Carabia, Julia, Boix, Joan, Tazón-Vega, Barbara, Iacoboni, Gloria, Bobillo, Sabela, Marín-Niebla, Ana, González, Marcos, Zenz, Thorsten, Crespo, Marta, Bosch, Francesc
Publicado 2022

Tumor necrosis factor receptor signaling is a driver of chronic lymphocytic leukemia that can be therapeutically targeted by the flavonoid wogonin

por Dürr, Claudia, Hanna, Bola S., Schulz, Angela, Lucas, Fabienne, Zucknick, Manuela, Benner, Axel, Clear, Andrew, Ohl, Sibylle, Öztürk, Selcen, Zenz, Thorsten, Stilgenbauer, Stephan, Li-Weber, Min, Krammer, Peter H., Gribben, John G., Lichter, Peter, Seiffert, Martina
Publicado 2018

Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia

por Ecker, Veronika, Stumpf, Martina, Brandmeier, Lisa, Neumayer, Tanja, Pfeuffer, Lisa, Engleitner, Thomas, Ringshausen, Ingo, Nelson, Nina, Jücker, Manfred, Wanninger, Stefan, Zenz, Thorsten, Wendtner, Clemens, Manske, Katrin, Steiger, Katja, Rad, Roland, Müschen, Markus, Ruland, Jürgen, Buchner, Maike
Publicado 2021