A non-traditional crystal-based compound screening method targeting the ATP binding site of Plasmodium falciparum GRP78 for identification of novel nucleoside analogues

por Mrozek, Alexander, Antoshchenko, Tetyana, Chen, Yun, Zepeda-Velázquez, Carlos, Smil, David, Kumar, Nirbhay, Lu, Hua, Park, Hee-Won
Publicado 2022

Truncated ring-A amaryllidaceae alkaloid modulates the host cell integrated stress response, exhibiting antiviral activity to HSV-1 and SARSCoV-2

por McNulty, James, Babu-Dokuburra, Chanti, Scattolon, Jon, Zepeda-Velazquez, Carlos, Wesesky, Maribeth A., Caldwell, Jill K., Zheng, Wenxiao, Milosevic, Jadranka, Kinchington, Paul R., Bloom, David C., Nimgaonkar, Vishwajit L., D’Aiuto, Leonardo
Publicado 2023

Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma

por Ensan, Deeba, Smil, David, Zepeda-Velázquez, Carlos A., Panagopoulos, Dimitrios, Wong, Jong Fu, Williams, Eleanor P., Adamson, Roslin, Bullock, Alex N., Kiyota, Taira, Aman, Ahmed, Roberts, Owen G., Edwards, Aled M., O’Meara, Jeff A., Isaac, Methvin B., Al-awar, Rima
Publicado 2020

R430: A potent inhibitor of DNA and RNA viruses

por D’Aiuto, Leonardo, McNulty, James, Hartline, Caroll, Demers, Matthew, Kalkeri, Raj, Wood, Joel, McClain, Lora, Chattopadhyay, Ansuman, Zhi, Yun, Naciri, Jennifer, Smith, Adam, Yolken, Robert, Chowdari, Kodavali, Zepeda-Velazquez, Carlos, Dokuburra, Chanti Babu, Marques, Ernesto, Ptak, Roger, Kinchington, Paul, Watkins, Simon, Prichard, Mark, Bloom, David, Nimgaonkar, Vishwajit
Publicado 2018

A chemical biology toolbox to study protein methyltransferases and epigenetic signaling

por Scheer, Sebastian, Ackloo, Suzanne, Medina, Tiago S., Schapira, Matthieu, Li, Fengling, Ward, Jennifer A., Lewis, Andrew M., Northrop, Jeffrey P., Richardson, Paul L., Kaniskan, H. Ümit, Shen, Yudao, Liu, Jing, Smil, David, McLeod, David, Zepeda-Velazquez, Carlos A., Luo, Minkui, Jin, Jian, Barsyte-Lovejoy, Dalia, Huber, Kilian V. M., De Carvalho, Daniel D., Vedadi, Masoud, Zaph, Colby, Brown, Peter J., Arrowsmith, Cheryl H.
Publicado 2019