Temporal transcriptional response to latency reversing agents identifies specific factors regulating HIV-1 viral transcriptional switch

por Venkatachari, Narasimhan J., Zerbato, Jennifer M., Jain, Siddhartha, Mancini, Allison E., Chattopadhyay, Ansuman, Sluis-Cremer, Nicolas, Bar-Joseph, Ziv, Ayyavoo, Velpandi
Publicado 2015

Factors associated with weak positive SARS-CoV-2 diagnosis by reverse transcriptase-quantitative polymerase chain reaction (RT-qPCR)

por Rawat, Priyank, Zerbato, Jennifer M., Rhodes, Ajantha, Chiu, Chris, Tran, Thomas, Rasmussen, Thomas A., Druce, Julian, Lewin, Sharon R., Roche, Michael
Publicado 2022

Markers of Immune Activation and Inflammation Are Associated with Higher Levels of Genetically-Intact HIV in HIV-HBV Co-Infected Individuals

por Wang, Xiao Qian, Zerbato, Jennifer M., Avihingsanon, Anchalee, Fisher, Katie, Schlub, Timothy, Rhodes, Ajantha, Audsley, Jennifer, Singh, Kasha P., Zhao, Wei, Lewin, Sharon R., Palmer, Sarah
Publicado 2022

Novel assay reveals a large inducible replication competent HIV-1 reservoir in resting CD4(+) T cells

por Gupta, Phalguni, Sanyal, Anwesha, Ratner, Deena, Ding, Ming, Zerbato, Jennifer M., Giacobbi, Nicholas, Venkatachari, Narasimhan J., Patterson, Bruce K., Chargin, Amanda, Chen, Yue, Mailliard, Robbie B., Rinaldo, Charles R., Sluis-Cremer, Nicolas
Publicado 2017

Integration in oncogenes plays only a minor role in determining the in vivo distribution of HIV integration sites before or during suppressive antiretroviral therapy

por Coffin, John M., Bale, Michael J., Wells, Daria, Guo, Shuang, Luke, Brian, Zerbato, Jennifer M., Sobolewski, Michele D., Sia, Twan, Shao, Wei, Wu, Xiaolin, Maldarelli, Frank, Kearney, Mary F., Mellors, John W., Hughes, Stephen H.
Publicado 2021

Reprogrammed CRISPR-Cas13b suppresses SARS-CoV-2 replication and circumvents its mutational escape through mismatch tolerance

por Fareh, Mohamed, Zhao, Wei, Hu, Wenxin, Casan, Joshua M. L., Kumar, Amit, Symons, Jori, Zerbato, Jennifer M., Fong, Danielle, Voskoboinik, Ilia, Ekert, Paul G., Rudraraju, Rajeev, Purcell, Damian F. J., Lewin, Sharon R., Trapani, Joseph A.
Publicado 2021

De novo design of CRISPR-Cas13b enables efficient silencing of SARS-CoV-2 variants and tumour pathogenic RNAs with near single-base precision

por Hu, Wenxin, Zhao, Wei, Kumar, Amit, Singh, Gurjeet Jagjeet, Qi, Shijiao, Casan, Josh, Shembery, Carolyn, Fong, Danielle, Zerbato, Jennifer M., Symons, Jori, Rudraraju, Rajeev, Purcell, Damian, Haber, Michelle, Voskoboinik, Ilia, Ekert, Paul G., Lewin, Sharon, Trapani, Joseph, Fareh, Mohamed
Publicado 2022

Multiply spliced HIV RNA is a predictive measure of virus production ex vivo and in vivo following reversal of HIV latency

por Zerbato, Jennifer M., Khoury, Georges, Zhao, Wei, Gartner, Matthew J., Pascoe, Rachel D., Rhodes, Ajantha, Dantanarayana, Ashanti, Gooey, Megan, Anderson, Jenny, Bacchetti, Peter, Deeks, Steven G., McMahon, James, Roche, Michael, Rasmussen, Thomas A., Purcell, Damian FJ, Lewin, Sharon R.
Publicado 2021

Persistence of envelopes in different CD4(+) T-cell subsets in antiretroviral therapy-suppressed people with HIV

por Gartner, Matthew J., Tumpach, Carolin, Dantanarayana, Ashanti, Stern, Jared, Zerbato, Jennifer M., Chang, J. Judy, Angelovich, Thomas A., Anderson, Jenny L., Symons, Jori, Deeks, Steve G., Flynn, Jacqueline K., Lewin, Sharon R., Churchill, Melissa J., Gorry, Paul R., Roche, Michael
Publicado 2023

Venetoclax, alone and in combination with the BH3 mimetic S63845, depletes HIV-1 latently infected cells and delays rebound in humanized mice

por Arandjelovic, Philip, Kim, Youry, Cooney, James P., Preston, Simon P., Doerflinger, Marcel, McMahon, James H., Garner, Sarah E., Zerbato, Jennifer M., Roche, Michael, Tumpach, Carolin, Ong, Jesslyn, Sheerin, Dylan, Smyth, Gordon K., Anderson, Jenny L., Allison, Cody C., Lewin, Sharon R., Pellegrini, Marc
Publicado 2023

Intrahepatic CXCL10 is strongly associated with liver fibrosis in HIV-Hepatitis B co-infection

por Singh, Kasha P., Zerbato, Jennifer M., Zhao, Wei, Braat, Sabine, Deleage, Claire, Tennakoon, G. Surekha, Mason, Hugh, Dantanarayana, Ashanti, Rhodes, Ajantha, Rhodes, Jake W., Torresi, Joe, Harman, Andrew N., Revill, Peter A., Crane, Megan, Estes, Jacob D., Avihingsanon, Anchalee, Lewin, Sharon R., Audsley, Jennifer
Publicado 2020

HIV DNA persists in hepatocytes in people with HIV-hepatitis B co-infection on antiretroviral therapy

por Zerbato, Jennifer M., Avihingsanon, Anchalee, Singh, Kasha P., Zhao, Wei, Deleage, Claire, Rosen, Elias, Cottrell, Mackenzie L., Rhodes, Ajantha, Dantanarayana, Ashanti, Tumpach, Carolin, Tennakoon, Surekha, Crane, Megan, Price, David J., Braat, Sabine, Mason, Hugh, Roche, Michael, Kashuba, Angela D.M., Revill, Peter A., Audsley, Jennifer, Lewin, Sharon R.
Publicado 2022

Diverse effects of interferon alpha on the establishment and reversal of HIV latency

por Van der Sluis, Renée M., Zerbato, Jennifer M., Rhodes, Jake W., Pascoe, Rachel D., Solomon, Ajantha, Kumar, Nitasha A., Dantanarayana, Ashanti I., Tennakoon, Surekha, Dufloo, Jérémy, McMahon, James, Chang, Judy J., Evans, Vanessa A., Hertzog, Paul J., Jakobsen, Martin R., Harman, Andrew N., Lewin, Sharon R., Cameron, Paul U.
Publicado 2020

Memory CD4(+) T cells that co-express PD1 and CTLA4 have reduced response to activating stimuli facilitating HIV latency

por Rasmussen, Thomas A., Zerbato, Jennifer M., Rhodes, Ajantha, Tumpach, Carolin, Dantanarayana, Ashanti, McMahon, James H., Lau, Jillian S.Y., Chang, J. Judy, Gubser, Celine, Brown, Wendy, Hoh, Rebecca, Krone, Melissa, Pascoe, Rachel, Chiu, Chris Y., Bramhall, Michael, Lee, Hyun Jae, Haque, Ashraful, Fromentin, Rèmi, Chomont, Nicolas, Milush, Jeffrey, Van der Sluis, Renee M., Palmer, Sarah, Deeks, Steven G., Cameron, Paul U., Evans, Vanessa, Lewin, Sharon R.
Publicado 2022

A clinical trial of non-invasive imaging with an anti-HIV antibody labelled with copper-64 in people living with HIV and uninfected controls

por McMahon, James H., Zerbato, Jennifer M., Lau, Jillian S.Y., Lange, Jaclyn L., Roche, Michael, Tumpach, Carolin, Dantanarayana, Ashanti, Rhodes, Ajantha, Chang, Judy, Rasmussen, Thomas A., Mackenzie, Charlene A., Alt, Karen, Hagenauer, Michelle, Roney, Janine, O‘Bryan, Jessica, Carey, Alexandra, McIntyre, Richard, Beech, Paul, O'Keefe, Graeme J., Wichmann, Christian W., Scott, Fiona E., Guo, Nancy, Lee, Sze-Ting, Liu, Zhanqi, Caskey, Marina, Nussenzweig, Michel C., Donnelly, Paul S., Egan, Gary, Hagemeyer, Christoph E., Scott, Andrew M., Lewin, Sharon R.
Publicado 2021