Continuous Fluorescent Sirtuin Activity Assay Based on Fatty Acylated Lysines

por Zessin, Matthes, Meleshin, Marat, Hilscher, Sebastian, Schiene-Fischer, Cordelia, Barinka, Cyril, Jung, Manfred, Schutkowski, Mike
Publicado 2023

Application of Ligand- and Structure-Based Prediction Models for the Design of Alkylhydrazide-Based HDAC3 Inhibitors as Novel Anti-Cancer Compounds

por Bülbül, Emre F., Robaa, Dina, Sun, Ping, Mahmoudi, Fereshteh, Melesina, Jelena, Zessin, Matthes, Schutkowski, Mike, Sippl, Wolfgang
Publicado 2023

Docking, Binding Free Energy Calculations and In Vitro Characterization of Pyrazine Linked 2-Aminobenzamides as Novel Class I Histone Deacetylase (HDAC) Inhibitors

por Bülbül, Emre F., Melesina, Jelena, Ibrahim, Hany S., Abdelsalam, Mohamed, Vecchio, Anita, Robaa, Dina, Zessin, Matthes, Schutkowski, Mike, Sippl, Wolfgang
Publicado 2022

Continuous Activity Assay for HDAC11 Enabling Reevaluation of HDAC Inhibitors

por Kutil, Zsófia, Mikešová, Jana, Zessin, Matthes, Meleshin, Marat, Nováková, Zora, Alquicer, Glenda, Kozikowski, Alan, Sippl, Wolfgang, Bařinka, Cyril, Schutkowski, Mike
Publicado 2019

Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic...

por Ibrahim, Hany S., Abdelsalam, Mohamed, Zeyn, Yanira, Zessin, Matthes, Mustafa, Al-Hassan M., Fischer, Marten A., Zeyen, Patrik, Sun, Ping, Bülbül, Emre F., Vecchio, Anita, Erdmann, Frank, Schmidt, Matthias, Robaa, Dina, Barinka, Cyril, Romier, Christophe, Schutkowski, Mike, Krämer, Oliver H., Sippl, Wolfgang
Publicado 2021