SAC1 degrades its lipid substrate PtdIns4P in the endoplasmic reticulum to maintain a steep chemical gradient with donor membranes

por Zewe, James P, Wills, Rachel C, Sangappa, Sahana, Goulden, Brady D, Hammond, Gerald RV
Publicado 2018

PI(4,5)P(2) diffuses freely in the plasma membrane even within high-density effector protein complexes

por Pacheco, Jonathan, Cassidy, Anna C., Zewe, James P., Wills, Rachel C., Hammond, Gerald R.V.
Publicado 2022

TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes

por Willett, Rose, Martina, José A., Zewe, James P., Wills, Rachel, Hammond, Gerald R. V., Puertollano, Rosa
Publicado 2017

A high-avidity biosensor reveals plasma membrane PI(3,4)P(2) is predominantly a class I PI3K signaling product

por Goulden, Brady D., Pacheco, Jonathan, Dull, Allyson, Zewe, James P., Deiters, Alexander, Hammond, Gerald R.V.
Publicado 2019

A novel homeostatic mechanism tunes PI(4,5)P(2)-dependent signaling at the plasma membrane

por Wills, Rachel C., Doyle, Colleen P., Zewe, James P., Pacheco, Jonathan, Hansen, Scott D., Hammond, Gerald R. V.
Publicado 2023

Probing the subcellular distribution of phosphatidylinositol reveals a surprising lack at the plasma membrane

por Zewe, James P., Miller, April M., Sangappa, Sahana, Wills, Rachel C., Goulden, Brady D., Hammond, Gerald R.V.
Publicado 2020

Gigaxonin is required for intermediate filament transport

por Renganathan, Bhuvanasundar, Zewe, James P., Cheng, Yuan, Paumier, Jean‐Michel, Kittisopikul, Mark, Ridge, Karen M., Opal, Puneet, Gelfand, Vladimir I.
Publicado 2023

PI(4,5)P(2) controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER–PM contact sites

por Sohn, Mira, Korzeniowski, Marek, Zewe, James P., Wills, Rachel C., Hammond, Gerald R.V., Humpolickova, Jana, Vrzal, Lukas, Chalupska, Dominika, Veverka, Vaclav, Fairn, Gregory D., Boura, Evzen, Balla, Tamas
Publicado 2018