Inhibitors of the Actin-Bundling Protein Fascin-1 Developed for Tumor Therapy Attenuate the T-Cell Stimulatory Properties of Dendritic Cells

por Zeyn, Yanira, Harms, Gregory, Tubbe, Ingrid, Montermann, Evelyn, Röhrig, Nadine, Hartmann, Maike, Grabbe, Stephan, Bros, Matthias
Publicado 2022

Histone deacetylase inhibitors modulate hormesis in leukemic cells with mutant FMS-like tyrosine kinase-3

por Zeyn, Yanira, Hausmann, Kristin, Halilovic, Melisa, Beyer, Mandy, Ibrahim, Hany S., Brenner, Walburgis, Mahboobi, Siavosh, Bros, Matthias, Sippl, Wolfgang, Krämer, Oliver H.
Publicado 2023

Liver Cell Type-Specific Targeting by Nanoformulations for Therapeutic Applications

por Kaps, Leonard, Limeres, María José, Schneider, Paul, Svensson, Malin, Zeyn, Yanira, Fraude, Silvia, Cacicedo, Maximiliano L., Galle, Peter R., Gehring, Stephan, Bros, Matthias
Publicado 2023

Oncogenic Kinase Cascades Induce Molecular Mechanisms That Protect Leukemic Cell Models from Lethal Effects of De Novo dNTP Synthesis Inhibition

por Pons, Miriam, Zeyn, Yanira, Zahn, Stella, Mahendrarajah, Nisintha, Page, Brent D. G., Gunning, Patrick T., Moriggl, Richard, Brenner, Walburgis, Butter, Falk, Krämer, Oliver H.
Publicado 2021

Enrichment Methods for Murine Liver Non-Parenchymal Cells Differentially Affect Their Immunophenotype and Responsiveness towards Stimulation

por Medina-Montano, Carolina, Cacicedo, Maximiliano Luis, Svensson, Malin, Limeres, Maria Jose, Zeyn, Yanira, Chaves-Giraldo, Jean Emiro, Röhrig, Nadine, Grabbe, Stephan, Gehring, Stephan, Bros, Matthias
Publicado 2022

Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3

por Wachholz, Vanessa, Mustafa, Al-Hassan M., Zeyn, Yanira, Henninger, Sven J., Beyer, Mandy, Dzulko, Melanie, Piée-Staffa, Andrea, Brachetti, Christina, Haehnel, Patricia S., Sellmer, Andreas, Mahboobi, Siavosh, Kindler, Thomas, Brenner, Walburgis, Nikolova, Teodora, Krämer, Oliver H.
Publicado 2021

Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic...

por Ibrahim, Hany S., Abdelsalam, Mohamed, Zeyn, Yanira, Zessin, Matthes, Mustafa, Al-Hassan M., Fischer, Marten A., Zeyen, Patrik, Sun, Ping, Bülbül, Emre F., Vecchio, Anita, Erdmann, Frank, Schmidt, Matthias, Robaa, Dina, Barinka, Cyril, Romier, Christophe, Schutkowski, Mike, Krämer, Oliver H., Sippl, Wolfgang
Publicado 2021