An APP ectodomain mutation outside of the Aβ domain promotes Aβ production in vitro and deposition in vivo

por Zhang, Xulun, Zhang, Can Martin, Prokopenko, Dmitry, Liang, Yingxia, Zhen, Sherri Y., Weigle, Ian Q., Han, Weinong, Aryal, Manish, Tanzi, Rudolph E., Sisodia, Sangram S.
Publicado 2021

Gut microbiota–driven brain Aβ amyloidosis in mice requires microglia

por Dodiya, Hemraj B., Lutz, Holly L., Weigle, Ian Q., Patel, Priyam, Michalkiewicz, Julia, Roman-Santiago, Carlos J., Zhang, Can Martin, Liang, Yingxia, Srinath, Abhinav, Zhang, Xulun, Xia, Jessica, Olszewski, Monica, Zhang, Xiaoqiong, Schipma, Matthew John, Chang, Eugene B., Tanzi, Rudolph E., Gilbert, Jack A., Sisodia, Sangram S.
Publicado 2021