A Novel Tetramethylpyrazine Derivative Protects Against Glutamate-Induced Cytotoxicity Through PGC1α/Nrf2 and PI3K/Akt Signaling Pathways

por Chen, Haiyun, Cao, Jie, Zhu, Zeyu, Zhang, Gaoxiao, Shan, Luchen, Yu, Pei, Wang, Yuqiang, Sun, Yewei, Zhang, Zaijun
Publicado 2018

Tetramethylpyrazine nitrone activates hypoxia-inducible factor and regulates iron homeostasis to improve renal anemia

por Cen, Yun, Wang, Peile, Gao, Fangfang, Jing, Mei, Zhang, Zaijun, Yi, Peng, Zhang, Gaoxiao, Sun, Yewei, Wang, Yuqiang
Publicado 2022

Andrographolide derivative AL-1 ameliorates TNBS-induced colitis in mice: involvement of NF-кB and PPAR-γ signaling pathways

por Yang, Yali, Yan, Hui, Jing, Mei, Zhang, Zaijun, Zhang, Gaoxiao, Sun, Yewei, Shan, Luchen, Yu, Pei, Wang, Yuqiang, Xu, Lipeng
Publicado 2016

Neuroprotective and neurogenic effects of novel tetramethylpyrazine derivative T-006 in Parkinson’s disease models through activating the MEF2-PGC1α and BDNF/CREB pathways

por Chen, Haiyun, Cao, Jie, Zha, Ling, Wang, Peile, Liu, Zheng, Guo, Baojian, Zhang, Gaoxiao, Sun, Yewei, Zhang, Zaijun, Wang, Yuqiang
Publicado 2020

Protective Effect of Edaravone in Primary Cerebellar Granule Neurons against Iodoacetic Acid-Induced Cell Injury

por Zhou, Xinhua, Zhu, Longjun, Wang, Liang, Guo, Baojian, Zhang, Gaoxiao, Sun, Yewei, Zhang, Zaijun, Lee, Simon Ming-Yuen, Yu, Pei, Wang, Yuqiang
Publicado 2015

Nephroprotective Effects of Tetramethylpyrazine Nitrone TBN in Diabetic Kidney Disease

por Jing, Mei, Cen, Yun, Gao, Fangfang, Wang, Ting, Jiang, Jinxin, Jian, Qianqian, Wu, Liangmiao, Guo, Baojian, Luo, Fangcheng, Zhang, Gaoxiao, Wang, Ying, Xu, Lipeng, Zhang, Zaijun, Sun, Yewei, Wang, Yuqiang
Publicado 2021

Therapeutic efficacy of novel memantine nitrate MN‐08 in animal models of Alzheimer’s disease

por Wu, Liangmiao, Zhou, Xinhua, Cao, Yiwan, MAK, Shing Hung, Zha, Ling, Li, Ning, Su, Zhiyang, Han, Yifan, Wang, Yuqiang, Man Hoi, Maggie Pui, Sun, Yewei, Zhang, Gaoxiao, Zhang, Zaijun, Yang, Xifei
Publicado 2021

Tetramethylpyrazine nitrone, a multifunctional neuroprotective agent for ischemic stroke therapy

por Zhang, Zaijun, Zhang, Gaoxiao, Sun, Yewei, Szeto, Samuel S. W., Law, Henry C. H., Quan, Quan, Li, Guohui, Yu, Pei, Sho, Eiketsu, Siu, Michael K. W., Lee, Simon M. Y., Chu, Ivan K., Wang, Yuqiang
Publicado 2016