Associating rare genetic variants with human diseases

por Zhang, Qunyuan
Publicado 2015

Methods for adjusting population structure and familial relatedness in association test for collective effect of multiple rare variants on quantitative traits

por Zhang, Qunyuan, Chung, Doyoung, Kraja, Aldi, Borecki, Ingrid I, Province, Michael A
Publicado 2011

Distance-based phenotypic association analysis of DNA sequence data

por Chung, Doyoung, Zhang, Qunyuan, Kraja, Aldi T, Borecki, Ingrid B, Province, Michael A
Publicado 2011

Burden of disease variants in participants of the long life family Study

por Stevenson, Meredith, Bae, Harold, Schupf, Nicole, Andersen, Stacy, Zhang, Qunyuan, Perls, Thomas, Sebastiani, Paola
Publicado 2015

Admixture mapping of coronary artery calcification in African Americans from the NHLBI family heart study

por Gomez, Felicia, Wang, Lihua, Abel, Haley, Zhang, Qunyuan, Province, Michael A, Borecki, Ingrid B
Publicado 2015

Erratum: Burden of disease variants in participants of the long life family study

por Stevenson, Meredith, Bae, Harold, Schupf, Nicole, Andersen, Stacy, Zhang, Qunyuan, Perls, Thomas, Sebastiani, Paola
Publicado 2015

Vasohibin-1 suppresses colon cancer

por Liu, Shuai, Han, Bing, Zhang, Qunyuan, Dou, Jie, Wang, Fang, Lin, Wenli, Sun, Yuping, Peng, Guangyong
Publicado 2015

Sequencing of idiopathic pulmonary fibrosis-related genes reveals independent single gene associations

por Coghlan, Meghan A, Shifren, Adrian, Huang, Howard J, Russell, Tonya D, Mitra, Robi D, Zhang, Qunyuan, Wegner, Daniel J, Cole, F Sessions, Hamvas, Aaron
Publicado 2014

CD4(+) and CD8(+) T cells have opposing roles in breast cancer progression and outcome

por Huang, Yi, Ma, Chunling, Zhang, Qunyuan, Ye, Jian, Wang, Fang, Zhang, Yanping, Hunborg, Pamela, Varvares, Mark A., Hoft, Daniel F., Hsueh, Eddy C., Peng, Guangyong
Publicado 2015

MuSiC: Identifying mutational significance in cancer genomes

por Dees, Nathan D., Zhang, Qunyuan, Kandoth, Cyriac, Wendl, Michael C., Schierding, William, Koboldt, Daniel C., Mooney, Thomas B., Callaway, Matthew B., Dooling, David, Mardis, Elaine R., Wilson, Richard K., Ding, Li
Publicado 2012

Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study

por Druley, Todd E., Wang, Lihua, Lin, Shiow J., Lee, Joseph H., Zhang, Qunyuan, Daw, E. Warwick, Abel, Haley J., Chasnoff, Sara E., Ramos, Enrique I., Levinson, Benjamin T., Thyagarajan, Bharat, Newman, Anne B., Christensen, Kaare, Mayeux, Richard, Province, Michael A.
Publicado 2016

BreakDancer: An algorithm for high resolution mapping of genomic structural variation

por Chen, Ken, Wallis, John W., McLellan, Michael D., Larson, David E., Kalicki, Joelle M., Pohl, Craig S., McGrath, Sean D., Wendl, Michael C., Zhang, Qunyuan, Locke, Devin P., Shi, Xiaoqi, Fulton, Robert S., Ley, Timothy J., Wilson, Richard K., Ding, Li, Mardis, Elaine R.
Publicado 2009

Persistent Gut Microbiota Immaturity in Malnourished Bangladeshi Children

por Subramanian, Sathish, Huq, Sayeeda, Yatsunenko, Tanya, Haque, Rashidul, Mahfuz, Mustafa, Alam, Mohammed A., Benezra, Amber, DeStefano, Joseph, Meier, Martin F., Muegge, Brian D., Barratt, Michael J., VanArendonk, Laura G., Zhang, Qunyuan, Province, Michael A., Petri, William A., Ahmed, Tahmeed, Gordon, Jeffrey I.
Publicado 2014

Mutational landscape and significance across 12 major cancer types

por Kandoth, Cyriac, McLellan, Michael D., Vandin, Fabio, Ye, Kai, Niu, Beifang, Lu, Charles, Xie, Mingchao, Zhang, Qunyuan, McMichael, Joshua F., Wyczalkowski, Matthew A., Leiserson, Mark D. M., Miller, Christopher A., Welch, John S., Walter, Matthew J., Wendl, Michael C., Ley, Timothy J., Wilson, Richard K., Raphael, Benjamin J., Ding, Li
Publicado 2013

Integrated Analysis of Germline and Somatic Variants in Ovarian Cancer

por Kanchi, Krishna L., Johnson, Kimberly J., Lu, Charles, McLellan, Michael D., Leiserson, Mark D.M., Wendl, Michael C., Zhang, Qunyuan, Koboldt, Daniel C., Xie, Mingchao, Kandoth, Cyriac, McMichael, Joshua F., Wyczalkowski, Matthew A., Larson, David E., Schmidt, Heather K., Miller, Christopher A., Fulton, Robert S., Spellman, Paul T., Mardis, Elaine R., Druley, Todd E., Graubert, Timothy A., Goodfellow, Paul J., Raphael, Benjamin J., Wilson, Richard K., Ding, Li
Publicado 2014

Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci

por Service, Susan K., Teslovich, Tanya M., Fuchsberger, Christian, Ramensky, Vasily, Yajnik, Pranav, Koboldt, Daniel C., Larson, David E., Zhang, Qunyuan, Lin, Ling, Welch, Ryan, Ding, Li, McLellan, Michael D., O'Laughlin, Michele, Fronick, Catrina, Fulton, Lucinda L., Magrini, Vincent, Swift, Amy, Elliott, Paul, Jarvelin, Marjo-Riitta, Kaakinen, Marika, McCarthy, Mark I., Peltonen, Leena, Pouta, Anneli, Bonnycastle, Lori L., Collins, Francis S., Narisu, Narisu, Stringham, Heather M., Tuomilehto, Jaakko, Ripatti, Samuli, Fulton, Robert S., Sabatti, Chiara, Wilson, Richard K., Boehnke, Michael, Freimer, Nelson B.
Publicado 2014

A Bivariate Genome-Wide Approach to Metabolic Syndrome: STAMPEED Consortium

por Kraja, Aldi T., Vaidya, Dhananjay, Pankow, James S., Goodarzi, Mark O., Assimes, Themistocles L., Kullo, Iftikhar J., Sovio, Ulla, Mathias, Rasika A., Sun, Yan V., Franceschini, Nora, Absher, Devin, Li, Guo, Zhang, Qunyuan, Feitosa, Mary F., Glazer, Nicole L., Haritunians, Talin, Hartikainen, Anna-Liisa, Knowles, Joshua W., North, Kari E., Iribarren, Carlos, Kral, Brian, Yanek, Lisa, O’Reilly, Paul F., McCarthy, Mark I., Jaquish, Cashell, Couper, David J., Chakravarti, Aravinda, Psaty, Bruce M., Becker, Lewis C., Province, Michael A., Boerwinkle, Eric, Quertermous, Thomas, Palotie, Leena, Jarvelin, Marjo-Riitta, Becker, Diane M., Kardia, Sharon L.R., Rotter, Jerome I., Chen, Yii-Der Ida, Borecki, Ingrid B.
Publicado 2011

Patterns and functional implications of rare germline variants across 12 cancer types

por Lu, Charles, Xie, Mingchao, Wendl, Michael C., Wang, Jiayin, McLellan, Michael D., Leiserson, Mark D. M., Huang, Kuan-lin, Wyczalkowski, Matthew A., Jayasinghe, Reyka, Banerjee, Tapahsama, Ning, Jie, Tripathi, Piyush, Zhang, Qunyuan, Niu, Beifang, Ye, Kai, Schmidt, Heather K., Fulton, Robert S., McMichael, Joshua F., Batra, Prag, Kandoth, Cyriac, Bharadwaj, Maheetha, Koboldt, Daniel C., Miller, Christopher A., Kanchi, Krishna L., Eldred, James M., Larson, David E., Welch, John S., You, Ming, Ozenberger, Bradley A., Govindan, Ramaswamy, Walter, Matthew J., Ellis, Matthew J., Mardis, Elaine R., Graubert, Timothy A., Dipersio, John F., Ley, Timothy J., Wilson, Richard K., Goodfellow, Paul J., Raphael, Benjamin J., Chen, Feng, Johnson, Kimberly J., Parvin, Jeffrey D., Ding, Li
Publicado 2015

NRXN3 Is a Novel Locus for Waist Circumference: A Genome-Wide Association Study from the CHARGE Consortium

por Heard-Costa, Nancy L., Zillikens, M. Carola, Monda, Keri L., Johansson, Åsa, Harris, Tamara B., Fu, Mao, Haritunians, Talin, Feitosa, Mary F., Aspelund, Thor, Eiriksdottir, Gudny, Garcia, Melissa, Launer, Lenore J., Smith, Albert V., Mitchell, Braxton D., McArdle, Patrick F., Shuldiner, Alan R., Bielinski, Suzette J., Boerwinkle, Eric, Brancati, Fred, Demerath, Ellen W., Pankow, James S., Arnold, Alice M., Chen, Yii-Der Ida, Glazer, Nicole L., McKnight, Barbara, Psaty, Bruce M., Rotter, Jerome I., Amin, Najaf, Campbell, Harry, Gyllensten, Ulf, Pattaro, Cristian, Pramstaller, Peter P., Rudan, Igor, Struchalin, Maksim, Vitart, Veronique, Gao, Xiaoyi, Kraja, Aldi, Province, Michael A., Zhang, Qunyuan, Atwood, Larry D., Dupuis, Josée, Hirschhorn, Joel N., Jaquish, Cashell E., O'Donnell, Christopher J., Vasan, Ramachandran S., White, Charles C., Aulchenko, Yurii S., Estrada, Karol, Hofman, Albert, Rivadeneira, Fernando, Uitterlinden, André G., Witteman, Jacqueline C. M., Oostra, Ben A., Kaplan, Robert C., Gudnason, Vilmundur, O'Connell, Jeffrey R., Borecki, Ingrid B., van Duijn, Cornelia M., Cupples, L. Adrienne, Fox, Caroline S., North, Kari E.
Publicado 2009

Genome Remodeling in a Basal-like Breast Cancer Metastasis and Xenograft

por Ding, Li, Ellis, Matthew J., Li, Shunqiang, Larson, David E., Chen, Ken, Wallis, John W., Harris, Christopher C., McLellan, Michael D., Fulton, Robert S., Fulton, Lucinda L., Abbott, Rachel M., Hoog, Jeremy, Dooling, David J., Koboldt, Daniel C., Schmidt, Heather, Kalicki, Joelle, Zhang, Qunyuan, Chen, Lei, Lin, Ling, Wendl, Michael C., McMichael, Joshua F., Magrini, Vincent J., Cook, Lisa, McGrath, Sean D., Vickery, Tammi L., Appelbaum, Elizabeth, DeSchryver, Katherine, Davies, Sherri, Guintoli, Therese, Lin, Li, Crowder, Robert, Tao, Yu, Snider, Jacqueline E., Smith, Scott M., Dukes, Adam F., Sanderson, Gabriel E., Pohl, Craig S., Delehaunty, Kim D., Fronick, Catrina C., Pape, Kimberley A., Reed, Jerry S., Robinson, Jody S., Hodges, Jennifer S., Schierding, William, Dees, Nathan D., Shen, Dong, Locke, Devin P., Wiechert, Madeline E., Eldred, James M., Peck, Josh B., Oberkfell, Benjamin J., Lolofie, Justin T., Du, Feiyu, Hawkins, Amy E., O'Laughlin, Michelle D., Bernard, Kelly E., Cunningham, Mark, Elliott, Glendoria, Mason, Mark D., Thompson, Dominic M., Ivanovich, Jennifer L., Goodfellow, Paul J., Perou, Charles M., Weinstock, George M., Aft, Rebecca, Watson, Mark, Ley, Timothy J., Wilson, Richard K., Mardis, Elaine R.
Publicado 2010