Discovery of Potent and Selective Covalent Protein Arginine Methyltransferase 5 (PRMT5) Inhibitors

por Lin, Hong, Wang, Min, Zhang, Yang W., Tong, Shuilong, Leal, Raul A., Shetty, Rupa, Vaddi, Kris, Luengo, Juan I.
Publicado 2019

Critical threshold levels of DNA methyltransferase 1 are required to maintain DNA methylation across the genome in human cancer cells

por Cai, Yi, Tsai, Hsing-Chen, Yen, Ray-Whay Chiu, Zhang, Yang W., Kong, Xiangqian, Wang, Wei, Xia, Limin, Baylin, Stephen B.
Publicado 2017