RNA-targeted small-molecule drug discoveries: a machine-learning perspective

por Xiao, Huan, Yang, Xin, Zhang, Yihao, Zhang, Zongkang, Zhang, Ge, Zhang, Bao-Ting
Publicado 2023

Current Pharmacological Strategies for Duchenne Muscular Dystrophy

por Yao, Shanshan, Chen, Zihao, Yu, Yuanyuan, Zhang, Ning, Jiang, Hewen, Zhang, Ge, Zhang, Zongkang, Zhang, Baoting
Publicado 2021

Drug Discovery of DKK1 Inhibitors

por Jiang, Hewen, Zhang, Zongkang, Yu, Yuanyuan, Chu, Hang Yin, Yu, Sifan, Yao, Shanshan, Zhang, Ge, Zhang, Bao-Ting
Publicado 2022

Recent Advances in SELEX Technology and Aptamer Applications in Biomedicine

por Zhuo, Zhenjian, Yu, Yuanyuan, Wang, Maolin, Li, Jie, Zhang, Zongkang, Liu, Jin, Wu, Xiaohao, Lu, Aiping, Zhang, Ge, Zhang, Baoting
Publicado 2017

A Loop‐Based and AGO‐Incorporated Virtual Screening Model Targeting AGO‐Mediated miRNA–mRNA Interactions for Drug Discovery to Rescue Bone Phenotype in Genetically Modified Mice...

por Zhuo, Zhenjian, Wan, Youyang, Guan, Daogang, Ni, Shuaijian, Wang, Luyao, Zhang, Zongkang, Liu, Jin, Liang, Chao, Yu, Yuanyuan, Lu, Aiping, Zhang, Ge, Zhang, Bao‐Ting
Publicado 2020

Targeting osteoblastic casein kinase-2 interacting protein-1 to enhance Smad-dependent BMP signaling and reverse bone formation reduction in glucocorticoid-induced osteoporosis

por Liu, Jin, Lu, Changwei, Wu, Xiaohao, Zhang, Zongkang, Li, Jie, Guo, Baosheng, Li, Defang, Liang, Chao, Dang, Lei, Pan, Xiaohua, Peng, Songlin, Lu, Aiping, Zhang, Baoting, Zhang, Ge
Publicado 2017

Combination of inflammation-related cytokines promotes long-term muscle stem cell expansion

por Fu, Xin, Xiao, Jun, Wei, Yuning, Li, Sheng, Liu, Yan, Yin, Jie, Sun, Kun, Sun, Hao, Wang, Huating, Zhang, Zongkang, Zhang, Bao-Ting, Sheng, Chun, Wang, Hongyan, Hu, Ping
Publicado 2015

Increased PLEKHO1 within osteoblasts suppresses Smad‐dependent BMP signaling to inhibit bone formation during aging

por Liu, Jin, Liang, Chao, Guo, Baosheng, Wu, Xiaohao, Li, Defang, Zhang, Zongkang, Zheng, Kang, Dang, Lei, He, Xiaojuan, Lu, Changwei, Peng, Songlin, Pan, Xiaohua, Zhang, Bao‐Ting, Lu, Aiping, Zhang, Ge
Publicado 2017

Drug discovery of sclerostin inhibitors

por Yu, Sifan, Li, Dijie, Zhang, Ning, Ni, Shuaijian, Sun, Meiheng, Wang, Luyao, Xiao, Huan, Liu, Dingdong, Liu, Jin, Yu, Yuanyuan, Zhang, Zongkang, Yeung, Samuel Tin Yui, Zhang, Shu, Lu, Aiping, Zhang, Zhenlin, Zhang, Baoting, Zhang, Ge
Publicado 2022

Osteoclastic miR-214 targets TRAF3 to contribute to osteolytic bone metastasis of breast cancer

por Liu, Jin, Li, Defang, Dang, Lei, Liang, Chao, Guo, Baosheng, Lu, Cheng, He, Xiaojuan, Cheung, Hilda Y. S., He, Bing, Liu, Biao, Li, Fangfei, Lu, Jun, Wang, Luyao, Shaikh, Atik Badshah, Jiang, Feng, Lu, Changwei, Peng, Songlin, Zhang, Zongkang, Zhang, Bao-Ting, Pan, Xiaohua, Xiao, Lianbo, Lu, Aiping, Zhang, Ge
Publicado 2017

Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation

por Li, Defang, Liu, Jin, Guo, Baosheng, Liang, Chao, Dang, Lei, Lu, Cheng, He, Xiaojuan, Cheung, Hilda Yeuk-Siu, Xu, Liang, Lu, Changwei, He, Bing, Liu, Biao, Shaikh, Atik Badshah, Li, Fangfei, Wang, Luyao, Yang, Zhijun, Au, Doris Wai-Ting, Peng, Songlin, Zhang, Zongkang, Zhang, Bao-Ting, Pan, Xiaohua, Qian, Airong, Shang, Peng, Xiao, Lianbo, Jiang, Baohong, Wong, Chris Kong-Chu, Xu, Jiake, Bian, Zhaoxiang, Liang, Zicai, Guo, De-an, Zhu, Hailong, Tan, Weihong, Lu, Aiping, Zhang, Ge
Publicado 2016