Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1,4,5-trisphosphate receptors

por Liang, Jingjing, Lyu, Jun, Zhao, Meng, Li, Dan, Zheng, Mingzhu, Fang, Yan, Zhao, Fangzhu, Lou, Jun, Guo, Chuansheng, Wang, Lie, Wang, Di, Liu, Wanli, Lu, Linrong
Publicado 2017

Author Correction: Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1,4,5-trisphosphate receptors

por Liang, Jingjing, Lyu, Jun, Zhao, Meng, Li, Dan, Zheng, Mingzhu, Fang, Yan, Zhao, Fangzhu, Lou, Jun, Guo, Chuansheng, Wang, Lie, Wang, Di, Liu, Wanli, Lu, Linrong
Publicado 2018

One-shot identification of SARS-CoV-2 S RBD escape mutants using yeast screening

por Urdaniz, Irene Francino, Steiner, Paul J., Kirby, Monica B., Zhao, Fangzhu, Haas, Cyrus M., Barman, Shawn, Rhodes, Emily R., Peng, Linghang, Sprenger, Kayla G., Jardine, Joseph G., Whitehead, Timothy A.
Publicado 2021

One-shot identification of SARS-CoV-2 S RBD escape mutants using yeast screening

por Francino-Urdaniz, Irene M., Steiner, Paul J., Kirby, Monica B., Zhao, Fangzhu, Haas, Cyrus M., Barman, Shawn, Rhodes, Emily R., Leonard, Alison C., Peng, Linghang, Sprenger, Kayla G., Jardine, Joseph G., Whitehead, Timothy A.
Publicado 2021

Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques

por Zhao, Fangzhu, Joyce, Collin, Burns, Alison, Nogal, Bartek, Cottrell, Christopher A., Ramos, Alejandra, Biddle, Trevor, Pauthner, Matthias, Nedellec, Rebecca, Qureshi, Huma, Mason, Rosemarie, Landais, Elise, Briney, Bryan, Ward, Andrew B., Burton, Dennis R., Sok, Devin
Publicado 2020

Structural basis of a public antibody response to SARS-CoV-2

por Yuan, Meng, Liu, Hejun, Wu, Nicholas C., Lee, Chang-Chun D., Zhu, Xueyong, Zhao, Fangzhu, Huang, Deli, Yu, Wenli, Hua, Yuanzi, Tien, Henry, Rogers, Thomas F., Landais, Elise, Sok, Devin, Jardine, Joseph G., Burton, Dennis R., Wilson, Ian A.
Publicado 2020

Structural basis of a shared antibody response to SARS-CoV-2

por Yuan, Meng, Liu, Hejun, Wu, Nicholas C., Lee, Chang-Chun D., Zhu, Xueyong, Zhao, Fangzhu, Huang, Deli, Yu, Wenli, Hua, Yuanzi, Tien, Henry, Rogers, Thomas F., Landais, Elise, Sok, Devin, Jardine, Joseph G., Burton, Dennis R., Wilson, Ian A.
Publicado 2020

From structure to sequence: Antibody discovery using cryoEM

por Antanasijevic, Aleksandar, Bowman, Charles A., Kirchdoerfer, Robert N., Cottrell, Christopher A., Ozorowski, Gabriel, Upadhyay, Amit A., Cirelli, Kimberly M., Carnathan, Diane G., Enemuo, Chiamaka A., Sewall, Leigh M., Nogal, Bartek, Zhao, Fangzhu, Groschel, Bettina, Schief, William R., Sok, Devin, Silvestri, Guido, Crotty, Shane, Bosinger, Steven E., Ward, Andrew B.
Publicado 2022

A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection

por Liu, Hejun, Yuan, Meng, Huang, Deli, Bangaru, Sandhya, Zhao, Fangzhu, Lee, Chang-Chun D., Peng, Linghang, Barman, Shawn, Zhu, Xueyong, Nemazee, David, Burton, Dennis R., van Gils, Marit J., Sanders, Rogier W., Kornau, Hans-Christian, Reincke, S. Momsen, Prüss, Harald, Kreye, Jakob, Wu, Nicholas C., Ward, Andrew B., Wilson, Ian A.
Publicado 2021

Fully synthetic platform to rapidly generate tetravalent bispecific nanobody–based immunoglobulins

por Misson Mindrebo, Laetitia, Liu, Hejun, Ozorowski, Gabriel, Tran, Quoc, Woehl, Jordan, Khalek, Irene, Smith, Jessica M., Barman, Shawn, Zhao, Fangzhu, Keating, Celina, Limbo, Oliver, Verma, Megan, Liu, Jingjia, Stanfield, Robyn L., Zhu, Xueyong, Turner, Hannah L., Sok, Devin, Huang, Po-Ssu, Burton, Dennis R., Ward, Andrew B., Wilson, Ian A., Jardine, Joseph G.
Publicado 2023

Diverse immunoglobulin gene usage and convergent epitope targeting in neutralizing antibody responses to SARS-CoV-2

por Zhou, Xiaojuan, Ma, Fengge, Xie, Jun, Yuan, Meng, Li, Yunqiao, Shaabani, Namir, Zhao, Fangzhu, Huang, Deli, Wu, Nicholas C., Lee, Chang-Chun D., Liu, Hejun, Li, Jiali, Chen, Zhonghui, Hong, Yazhen, Liu, Wen-Hsien, Xiao, Nengming, Burton, Dennis R., Tu, Haijian, Li, Hang, Chen, Xin, Teijaro, John R., Wilson, Ian A., Xiao, Changchun, Huang, Zhe
Publicado 2021

Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways

por Zhao, Fangzhu, Keating, Celina, Ozorowski, Gabriel, Shaabani, Namir, Francino-Urdaniz, Irene M., Barman, Shawn, Limbo, Oliver, Burns, Alison, Zhou, Panpan, Ricciardi, Michael J., Woehl, Jordan, Tran, Quoc, Turner, Hannah L., Peng, Linghang, Huang, Deli, Nemazee, David, Andrabi, Raiees, Sok, Devin, Teijaro, John R., Whitehead, Timothy A., Ward, Andrew B., Burton, Dennis R., Jardine, Joseph G.
Publicado 2022

Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies

por Joyce, Collin, Murrell, Sasha, Murrell, Ben, Omorodion, Oluwarotimi, Ver, Lorena S., Carrico, Nancy, Bastidas, Raiza, Nedellec, Rebecca, Bick, Michael, Woehl, Jordan, Zhao, Fangzhu, Burns, Alison, Barman, Shawn, Appel, Michael, Ramos, Alejandra, Wickramasinghe, Lalinda, Eren, Kemal, Vollbrecht, Thomas, Smith, Davey M., Kosakovsky Pond, Sergei L., McBride, Ryan, Worth, Charli, Batista, Facundo, Sok, Devin, Poignard, Pascal, Briney, Bryan, Wilson, Ian A., Landais, Elise, Burton, Dennis R.
Publicado 2023

Rapid isolation of potent SARS-CoV-2 neutralizing antibodies and protection in a small animal model

por Rogers, Thomas F., Zhao, Fangzhu, Huang, Deli, Beutler, Nathan, Burns, Alison, He, Wan-ting, Limbo, Oliver, Smith, Chloe, Song, Ge, Woehl, Jordan, Yang, Linlin, Abbott, Robert K., Callaghan, Sean, Garcia, Elijah, Hurtado, Jonathan, Parren, Mara, Peng, Linghang, Ricketts, James, Ricciardi, Michael J., Rawlings, Stephen A., Smith, Davey M., Nemazee, David, Teijaro, John R., Voss, James E., Andrabi, Raiees, Briney, Bryan, Landais, Elise, Sok, Devin, Jardine, Joseph G., Burton, Dennis R.
Publicado 2020

A combination of potently neutralizing monoclonal antibodies isolated from an Indian convalescent donor protects against the SARS-CoV-2 Delta variant

por Hingankar, Nitin, Deshpande, Suprit, Das, Payel, Rizvi, Zaigham Abbas, Wibmer, Constantinos Kurt, Mashilo, Poppy, Ansari, Mohammed Yousuf, Burns, Alison, Barman, Shawn, Zhao, Fangzhu, Mukherjee, Sohini, Torres, Jonathan L., Chattopadhyay, Souvick, Mehdi, Farha, Sutar, Jyoti, Rathore, Deepak Kumar, Pargai, Kamal, Singh, Janmejay, Sonar, Sudipta, Jakhar, Kamini, Dandotiya, Jyotsna, Bhattacharyya, Sankar, Mani, Shailendra, Samal, Sweety, Singh, Savita, Kshetrapal, Pallavi, Thiruvengadam, Ramachandran, Batra, Gaurav, Medigeshi, Guruprasad, Ward, Andrew B., Bhatnagar, Shinjini, Awasthi, Amit, Sok, Devin, Bhattacharya, Jayanta
Publicado 2022

Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus

por Zhao, Fangzhu, Berndsen, Zachary T., Pedreño-Lopez, Nuria, Burns, Alison, Allen, Joel D., Barman, Shawn, Lee, Wen-Hsin, Chakraborty, Srirupa, Gnanakaran, Sandrasegaram, Sewall, Leigh M., Ozorowski, Gabriel, Limbo, Oliver, Song, Ge, Yong, Peter, Callaghan, Sean, Coppola, Jessica, Weisgrau, Kim L., Lifson, Jeffrey D., Nedellec, Rebecca, Voigt, Thomas B., Laurino, Fernanda, Louw, Johan, Rosen, Brandon C., Ricciardi, Michael, Crispin, Max, Desrosiers, Ronald C., Rakasz, Eva G., Watkins, David I., Andrabi, Raiees, Ward, Andrew B., Burton, Dennis R., Sok, Devin
Publicado 2022

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

por Rogers, Thomas F., Zhao, Fangzhu, Huang, Deli, Beutler, Nathan, Burns, Alison, He, Wan-ting, Limbo, Oliver, Smith, Chloe, Song, Ge, Woehl, Jordan, Yang, Linlin, Abbott, Robert K., Callaghan, Sean, Garcia, Elijah, Hurtado, Jonathan, Parren, Mara, Peng, Linghang, Ramirez, Sydney, Ricketts, James, Ricciardi, Michael J., Rawlings, Stephen A., Wu, Nicholas C., Yuan, Meng, Smith, Davey M., Nemazee, David, Teijaro, John R., Voss, James E., Wilson, Ian A., Andrabi, Raiees, Briney, Bryan, Landais, Elise, Sok, Devin, Jardine, Joseph G., Burton, Dennis R.
Publicado 2020

Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques

por He, Wan-ting, Yuan, Meng, Callaghan, Sean, Musharrafieh, Rami, Song, Ge, Silva, Murillo, Beutler, Nathan, Lee, Wen-Hsin, Yong, Peter, Torres, Jonathan L., Melo, Mariane, Zhou, Panpan, Zhao, Fangzhu, Zhu, Xueyong, Peng, Linghang, Huang, Deli, Anzanello, Fabio, Ricketts, James, Parren, Mara, Garcia, Elijah, Ferguson, Melissa, Rinaldi, William, Rawlings, Stephen A., Nemazee, David, Smith, Davey M., Briney, Bryan, Safonova, Yana, Rogers, Thomas F., Dan, Jennifer M., Zhang, Zeli, Weiskopf, Daniela, Sette, Alessandro, Crotty, Shane, Irvine, Darrell J., Ward, Andrew B., Wilson, Ian A., Burton, Dennis R., Andrabi, Raiees
Publicado 2022

The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2

por Huang, Ruiqi, Warner Jenkins, Gabrielle, Kim, Yunjeong, Stanfield, Robyn L., Singh, Amrinder, Martinez-Yamout, Maria, Kroon, Gerard J., Torres, Jonathan L., Jackson, Abigail M., Kelley, Abigail, Shaabani, Namir, Zeng, Baisen, Bacica, Michael, Chen, Wen, Warner, Christopher, Radoicic, Jasmina, Joh, Joongho, Dinali Perera, Krishani, Sang, Huldah, Kim, Tae, Yao, Jianxiu, Zhao, Fangzhu, Sok, Devin, Burton, Dennis R., Allen, Jeff, Harriman, William, Mwangi, Waithaka, Chung, Donghoon, Teijaro, John R., Ward, Andrew B., Dyson, H. Jane, Wright, Peter E., Wilson, Ian A., Chang, Kyeong-Ok, McGregor, Duncan, Smider, Vaughn V.
Publicado 2023