Circulating FGF21 proteolytic processing mediated by fibroblast activation protein

por Zhen, Eugene Y., Jin, Zhaoyan, Ackermann, Bradley L., Thomas, Melissa K., Gutierrez, Jesus A.
Publicado 2016

Decoding the role of angiopoietin-like protein 4/8 complex–mediated plasmin generation in the regulation of LPL activity

por Chen, Yan Q., Zhen, Eugene Y., Russell, Anna M., Ehsani, Mariam, Siegel, Robert W., Qian, Yuewei, Konrad, Robert J.
Publicado 2023

Angiopoietin-like protein 4/8 complex-mediated plasmin generation leads to cleavage of the complex and restoration of LPL activity

por Zhen, Eugene Y., Chen, Yan Q., Russell, Anna M., Ehsani, Mariam, Siegel, Robert W., Qian, Yuewei, Konrad, Robert J.
Publicado 2023

ApoA5 lowers triglyceride levels via suppression of ANGPTL3/8-mediated LPL inhibition

por Chen, Yan Q., Pottanat, Thomas G., Zhen, Eugene Y., Siegel, Robert W., Ehsani, Mariam, Qian, Yue-Wei, Konrad, Robert J.
Publicado 2021

Angiopoietin-like protein 8 differentially regulates ANGPTL3 and ANGPTL4 during postprandial partitioning of fatty acids

por Chen, Yan Q., Pottanat, Thomas G., Siegel, Robert W., Ehsani, Mariam, Qian, Yue-Wei, Zhen, Eugene Y., Regmi, Ajit, Roell, William C., Guo, Haihong, Luo, M. Jane, Gimeno, Ruth E., van’t Hooft, Ferdinand, Konrad, Robert J.
Publicado 2020

An anti-ANGPTL3/8 antibody decreases circulating triglycerides by binding to a LPL-inhibitory leucine zipper-like motif

por Balasubramaniam, Deepa, Schroeder, Oliver, Russell, Anna M., Fitchett, Jonathan R., Austin, Aaron K., Beyer, Thomas P., Chen, Yan Q., Day, Jonathan W., Ehsani, Mariam, Heng, Aik Roy, Zhen, Eugene Y., Davies, Julian, Glaesner, Wolfgang, Jones, Bryan E., Siegel, Robert W., Qian, Yue-Wei, Konrad, Robert J.
Publicado 2022

Hypertriglyceridemia in Apoa5(–/–) mice results from reduced amounts of lipoprotein lipase in the capillary lumen

por Yang, Ye, Beigneux, Anne P., Song, Wenxin, Nguyen, Le Phuong, Jung, Hyesoo, Tu, Yiping, Weston, Thomas A., Tran, Caitlyn M., Xie, Katherine, Yu, Rachel G., Tran, Anh P., Miyashita, Kazuya, Nakajima, Katsuyuki, Murakami, Masami, Chen, Yan Q., Zhen, Eugene Y., Kim, Joonyoung R., Kim, Paul H., Birrane, Gabriel, Tontonoz, Peter, Ploug, Michael, Konrad, Robert J., Fong, Loren G., Young, Stephen G.
Publicado 2023