Focal adhesion kinase is activated by microtubule‐depolymerizing agents and regulates membrane blebbing in human endothelial cells

por Zheng, Yan‐Bo, Gong, Jian‐Hua, Zhen, Yong‐Su
Publicado 2020

A Multifunctional Drug Combination Shows Highly Potent Therapeutic Efficacy against Human Cancer Xenografts in Athymic Mice

por Liu, Xiu-Jun, Zheng, Yan-Bo, Li, Yi, Wu, Shu-Ying, Zhen, Yong-Su
Publicado 2014

An EGFR/HER2-Bispecific and Enediyne-Energized Fusion Protein Shows High Efficacy against Esophageal Cancer

por Guo, Xiao-Fang, Zhu, Xiao-Fei, Yang, Wan-Cai, Zhang, Sheng-Hua, Zhen, Yong-Su
Publicado 2014

The ionophore antibiotic gramicidin A inhibits pancreatic cancer stem cells associated with CD47 down-regulation

por Wang, Rui-Qi, Geng, Jing, Sheng, Wei-Jin, Liu, Xiu-Jun, Jiang, Min, Zhen, Yong-Su
Publicado 2019

Small antibody fusion proteins with complementarity-determining regions and lidamycin for tumor targeting therapy

por ZHONG, GEN-SHEN, WU, MIN-NA, GUO, XIAO-FANG, XU, ZHI-SHAN, ZHANG, SHENG-HUA, ZHEN, YONG-SU
Publicado 2013

An engineered TIMP2-based and enediyne-integrated fusion protein for targeting MMP-14 shows potent antitumor efficacy

por Xu, Jian, Liu, Xiu-Jun, Li, Liang, Zhang, Sheng-Hua, Li, Yi, Gao, Rui-Juan, Zhen, Yong-Su
Publicado 2015

A new HDAC inhibitor cinnamoylphenazine shows antitumor activity in association with intensive macropinocytosis

por Zhu, Bing-yan, Shang, Bo-yang, Du, Yue, Li, Yi, Li, Liang, Xu, Xian-dong, Zhen, Yong-su
Publicado 2017

A recombinantly tailored β-defensin that displays intensive macropinocytosis-mediated uptake exerting potent efficacy against K-Ras mutant pancreatic cancer

por Du, Yue, Shang, Bo-yang, Sheng, Wei-jin, Zhang, Sheng-hua, Li, Yi, Miao, Qing-fang, Zhen, Yong-su
Publicado 2016

Mithramycin-loaded mPEG-PLGA nanoparticles exert potent antitumor efficacy against pancreatic carcinoma

por Liu, Xu-Jie, Li, Liang, Liu, Xiu-Jun, Li, Yi, Zhao, Chun-Yan, Wang, Rui-Qi, Zhen, Yong-Su
Publicado 2017

Development of a novel multi-functional integrated bioconjugate effectively targeting K-Ras mutant pancreatic cancer

por Wang, Yang-Yang, Li, Liang, Liu, Xiu-Jun, Miao, Qing-Fang, Li, Yi, Zhang, Meng-Ran, Zhen, Yong-Su
Publicado 2022

Excellent effects and possible mechanisms of action of a new antibody–drug conjugate against EGFR-positive triple-negative breast cancer

por Zhou, Dan-Dan, Bai, Wei-Qi, Zhai, Xiao-Tian, Sun, Li-Ping, Zhen, Yong-Su, Li, Zhuo-Rong, Miao, Qing-Fang
Publicado 2021

Genetically engineered endostatin-lidamycin fusion proteins effectively inhibit tumor growth and metastasis

por Jiang, Wen-guo, Lu, Xin-an, Shang, Bo-yang, Fu, Yan, Zhang, Sheng-hua, Zhou, Daifu, Li, Liang, Li, Yi, Luo, Yongzhang, Zhen, Yong-su
Publicado 2013

A bispecific enediyne-energized fusion protein targeting both epidermal growth factor receptor and insulin-like growth factor 1 receptor showing enhanced antitumor efficacy against...

por Guo, Xiao-Fang, Zhu, Xiao-Fei, Cao, Hai-Ying, Zhong, Gen-Shen, Li, Liang, Deng, Bao-Guo, Chen, Ping, Wang, Pei-Zhen, Miao, Qing-Fang, Zhen, Yong-Su
Publicado 2017

Intensive fibrosarcoma-binding capability of the reconstituted analog and its antitumor activity

por Xu, Jian, Du, Yue, Liu, Wen-Juan, Li, Liang, Li, Yi, Wang, Xiao-Fei, Yi, Hong-Fei, Shan, Chuan-Kun, Xia, Gui-Min, Liu, Xiu-Jun, Zhen, Yong-Su
Publicado 2017

EZH2 mediates lidamycin-induced cellular senescence through regulating p21 expression in human colon cancer cells

por Sha, Ming-Quan, Zhao, Xiao-Li, Li, Liang, Li, Li-Hui, Li, Yi, Dong, Tian-Geng, Niu, Wei-Xin, Jia, Li-Jun, Shao, Rong-Guang, Zhen, Yong-Su, Wang, Zhen
Publicado 2016

A Novel Nitrobenzoate Microtubule Inhibitor that Overcomes Multidrug Resistance Exhibits Antitumor Activity

por Zheng, Yan-Bo, Gong, Jian-Hua, Liu, Xiu-Jun, Wu, Shu-Ying, Li, Yi, Xu, Xian-Dong, Shang, Bo-Yang, Zhou, Jin-Ming, Zhu, Zhi-Ling, Si, Shu-Yi, Zhen, Yong-Su
Publicado 2016

An EGFR‐targeting antibody–drug conjugate LR004‐VC‐MMAE: potential in esophageal squamous cell carcinoma and other malignancies

por Hu, Xin‐yue, Wang, Rong, Jin, Jie, Liu, Xiu‐jun, Cui, A‐long, Sun, Lian‐qi, Li, Yan‐ping, Li, Yi, Wang, Yu‐cheng, Zhen, Yong‐su, Miao, Qing‐fang, Li, Zhuo‐rong
Publicado 2018