Structural Basis of Main Proteases of Coronavirus Bound to Drug Candidate PF-07304814

por Li, Jian, Lin, Cheng, Zhou, Xuelan, Zhong, Fanglin, Zeng, Pei, McCormick, Peter J., Jiang, Haihai, Zhang, Jin
Publicado 2022

Crystal structure of SARS-CoV-2 main protease in complex with the natural product inhibitor shikonin illuminates a unique binding mode

por Li, Jian, Zhou, Xuelan, Zhang, Yan, Zhong, Fanglin, Lin, Cheng, McCormick, Peter J., Jiang, Feng, Luo, Jun, Zhou, Huan, Wang, Qisheng, Fu, Yang, Duan, Jingjing, Zhang, Jin
Publicado 2021

Structural Basis of the Main Proteases of Coronavirus Bound to Drug Candidate PF-07321332

por Li, Jian, Lin, Cheng, Zhou, Xuelan, Zhong, Fanglin, Zeng, Pei, Yang, Yang, Zhang, Yuting, Yu, Bo, Fan, Xiaona, McCormick, Peter J., Fu, Rui, Fu, Yang, Jiang, Haihai, Zhang, Jin
Publicado 2022

Structure of SARS-CoV-2 main protease in the apo state

por Zhou, Xuelan, Zhong, Fanglin, Lin, Cheng, Hu, Xiaohui, Zhang, Yan, Xiong, Bing, Yin, Xiushan, Fu, Jinheng, He, Wei, Duan, Jingjing, Fu, Yang, Zhou, Huan, McCormick, Peter J., Wang, Qisheng, Li, Jian, Zhang, Jin
Publicado 2020

Structure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus

por Zhang, Yuting, Gao, Hongxia, Hu, Xiaohui, Wang, Qisheng, Zhong, Fanglin, Zhou, Xuelan, Lin, Cheng, Yang, Yang, Wei, Junkang, Du, Weian, Huang, Huaiqiu, Zhou, Huan, He, Wei, Zhang, Hua, Zhang, Yuting, McCormick, Peter J., Fu, Jinheng, Wang, Dan, Fu, Yang, Lu, Xiaolu, Zhang, Tengfei, Duan, Jingjing, Qin, Bingjie, Jiang, Haihai, Luo, Jun, Zhang, Yan, Chen, Qi, Luo, Qunfeng, Cheng, Lin, Zhang, Zheng, Zhang, Jin, Li, Jian
Publicado 2022