SAT-653 Exploring the Role of Brown Adipokines on Hepatic Insulin Resistance Using a Microfluidic Organ-On-Chip

por Tanataweethum, Nida, Lee, Chaeeun, Trang, Allyson, Zhong, Franklin, Kim, Kihwan, Mehta, Jhalak, Cohen, Ronald Nelson, Bhushan, Abhinav
Publicado 2020

Structural and biochemical mechanisms of NLRP1 inhibition by DPP9

por Huang, Menghang, Zhang, Xiaoxiao, Toh, Gee Ann, Gong, Qin, Wang, Jia, Han, Zhifu, Wu, Bin, Zhong, Franklin, Chai, Jijie
Publicado 2021

Visualization of accessible cholesterol using a GRAM domain-based biosensor

por Koh, Dylan Hong Zheng, Naito, Tomoki, Na, Minyoung, Yeap, Yee Jie, Rozario, Pritisha, Zhong, Franklin L., Lim, Kah-Leong, Saheki, Yasunori
Publicado 2023

Structural basis of RIP2 activation and signaling

por Gong, Qin, Long, Ziqi, Zhong, Franklin L., Teo, Daniel Eng Thiam, Jin, Yibo, Yin, Zhan, Boo, Zhao Zhi, Zhang, Yaming, Zhang, Jiawen, Yang, Renliang, Bhushan, Shashi, Reversade, Bruno, Li, Zongli, Wu, Bin
Publicado 2018

Skin models for cutaneous melioidosis reveal Burkholderia infection dynamics at wound’s edge with inflammasome activation, keratinocyte extrusion and epidermal detachment

por Ku, Joanne Wei Kay, Marsh, Supatra Tharinee, Nai, Mui Hoon, Robinson, Kim Samirah, Teo, Daniel Eng Thiam, Zhong, Franklin Lei, Brown, Katherine A., Lim, Thiam Chye, Lim, Chwee Teck, Gan, Yunn-Hwen
Publicado 2021

Viral proteases activate the CARD8 inflammasome in the human cardiovascular system

por Nadkarni, Rhea, Chu, Wern Cui, Lee, Cheryl Q.E., Mohamud, Yasir, Yap, Lynn, Toh, Gee Ann, Beh, Sheryl, Lim, Radiance, Fan, Yiyun Michelle, Zhang, Yizhuo Lyanne, Robinson, Kim, Tryggvason, Karl, Luo, Honglin, Zhong, Franklin, Ho, Lena
Publicado 2022

A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability

por Chia, Poh Hui, Zhong, Franklin Lei, Niwa, Shinsuke, Bonnard, Carine, Utami, Kagistia Hana, Zeng, Ruizhu, Lee, Hane, Eskin, Ascia, Nelson, Stanley F, Xie, William H, Al-Tawalbeh, Samah, El-Khateeb, Mohammad, Shboul, Mohammad, Pouladi, Mahmoud A, Al-Raqad, Mohammed, Reversade, Bruno
Publicado 2018

Telomere shortening and loss of self-renewal in dyskeratosis congenita iPS cells

por Batista, Luis F.Z., Pech, Matthew F., Zhong, Franklin L., Nguyen, Ha Nam, Xie, Kathleen T., Zaug, Arthur J., Crary, Sharon M., Choi, Jinkuk, Sebastiano, Vittorio, Cherry, Athena, Giri, Neelam, Wernig, Marius, Alter, Blanche P., Cech, Thomas R., Savage, Sharon A., Reijo Pera, Renee A., Artandi, Steven E.
Publicado 2011

Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8

por Gong, Qin, Robinson, Kim, Xu, Chenrui, Huynh, Phuong Thao, Chong, Kelvin Han Chung, Tan, Eddie Yong Jun, Zhang, Jiawen, Boo, Zhao Zhi, Teo, Daniel Eng Thiam, Lay, Kenneth, Zhang, Yaming, Lim, John Soon Yew, Goh, Wah Ing, Wright, Graham, Zhong, Franklin L., Reversade, Bruno, Wu, Bin
Publicado 2021

EEF2-inactivating toxins engage the NLRP1 inflammasome and promote epithelial barrier disruption

por Pinilla, Miriam, Mazars, Raoul, Vergé, Romain, Gorse, Leana, Paradis, Margaux, Suire, Bastien, Santoni, Karin, Robinson, Kim Samirah, Toh, Gee Ann, Prouvensier, Laure, Leon-Icaza, Stephen Adonai, Hessel, Audrey, Péricat, David, Murris, Marlène, Guet-Revillet, Hélène, Henras, Anthony, Buyck, Julien, Ravet, Emmanuel, Zhong, Franklin L., Cougoule, Céline, Planès, Rémi, Meunier, Etienne
Publicado 2023

Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity

por Lee, Cheryl Q. E., Kerouanton, Baptiste, Chothani, Sonia, Zhang, Shan, Chen, Ying, Mantri, Chinmay Kumar, Hock, Daniella Helena, Lim, Radiance, Nadkarni, Rhea, Huynh, Vinh Thang, Lim, Daryl, Chew, Wei Leong, Zhong, Franklin L., Stroud, David Arthur, Schafer, Sebastian, Tergaonkar, Vinay, St John, Ashley L., Rackham, Owen J. L., Ho, Lena
Publicado 2021