Role of thermogenic adipose tissue in lipid metabolism and atherosclerotic cardiovascular disease: lessons from studies in mice and humans

por Ying, Zhixiong, Tramper, Naomi, Zhou, Enchen, Boon, Mariëtte R, Rensen, Patrick C N, Kooijman, Sander
Publicado 2022

Myeloperoxidase-oxidized high density lipoprotein impairs atherosclerotic plaque stability by inhibiting smooth muscle cell migration

por Zhou, Boda, Zu, Lingyun, Chen, Yong, Zheng, Xilong, Wang, Yuhui, Pan, Bing, Dong, Min, Zhou, Enchen, Zhao, Mingming, Zhang, Youyi, Zheng, Lemin, Gao, Wei
Publicado 2017

High density lipoprotein promotes proliferation of adipose-derived stem cells via S1P1 receptor and Akt, ERK1/2 signal pathways

por Shen, Haitao, Zhou, Enchen, Wei, Xiujing, Fu, Zhiwei, Niu, Chenguang, Li, Yang, Pan, Bing, Mathew, Anna V, Wang, Xu, Pennathur, Subramaniam, Zheng, Lemin, Wang, Yongyu
Publicado 2015

Macrophage Foam Cell–Derived Extracellular Vesicles Promote Vascular Smooth Muscle Cell Migration and Adhesion

por Niu, Chenguang, Wang, Xu, Zhao, Mingming, Cai, Tanxi, Liu, Peibin, Li, Jizhao, Willard, Belinda, Zu, Lingyun, Zhou, Enchen, Li, Yufeng, Pan, Bing, Yang, Fuquan, Zheng, Lemin
Publicado 2016

Pharmacological treatment with FGF21 strongly improves plasma cholesterol metabolism to reduce atherosclerosis

por Liu, Cong, Schönke, Milena, Zhou, Enchen, Li, Zhuang, Kooijman, Sander, Boon, Mariëtte R, Larsson, Mikael, Wallenius, Kristina, Dekker, Niek, Barlind, Louise, Peng, Xiao-Rong, Wang, Yanan, Rensen, Patrick C N
Publicado 2021

Discrimination of cell-intrinsic and environment-dependent effects of natural genetic variation on Kupffer cell epigenomes and transcriptomes

por Bennett, Hunter, Troutman, Ty D., Zhou, Enchen, Spann, Nathanael J., Link, Verena M., Seidman, Jason S., Nickl, Christian K., Abe, Yohei, Sakai, Mashito, Pasillas, Martina P., Marlman, Justin M., Guzman, Carlos, Hosseini, Mojgan, Schnabl, Bernd, Glass, Christopher K.
Publicado 2023

Colesevelam enhances the beneficial effects of brown fat activation on hyperlipidaemia and atherosclerosis development

por Zhou, Enchen, Hoeke, Geerte, Li, Zhuang, Eibergen, Arthur C, Schonk, Amber W, Koehorst, Martijn, Boverhof, Renze, Havinga, Rick, Kuipers, Folkert, Coskun, Tamer, Boon, Mariëtte R, Groen, Albert K, Rensen, Patrick C N, Berbée, Jimmy F P, Wang, Yanan
Publicado 2020

Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation

por Zhou, Enchen, Ge, Xiaoke, Nakashima, Hiroyuki, Li, Rumei, van der Zande, Hendrik J P, Liu, Cong, Li, Zhuang, Müller, Christoph, Bracher, Franz, Mohammed, Yassene, de Boer, Jan Freark, Kuipers, Folkert, Guigas, Bruno, Glass, Christopher K, Rensen, Patrick C N, Giera, Martin, Wang, Yanan
Publicado 2023

A Systems Analysis of Phenotype Heterogeneity in APOE*3Leiden.CETP Mice Induced by Long-Term High-Fat High-Cholesterol Diet Feeding

por Paalvast, Yared, Zhou, Enchen, Rozendaal, Yvonne J. W., Wang, Yanan, Gerding, Albert, van Dijk, Theo H., de Boer, Jan Freark, Rensen, Patrick C. N., van Dijk, Ko Willems, Kuivenhoven, Jan A., Bakker, Barbara M., van Riel, Natal A. W., Groen, Albert K.
Publicado 2022

Deletion of haematopoietic Dectin-2 or CARD9 does not protect from atherosclerosis development under hyperglycaemic conditions

por Thiem, Kathrin, Hoeke, Geerte, Zhou, Enchen, Hijmans, Anneke, Houben, Tom, Boels, Margien G, Mol, Isabel M, Lutgens, Esther, Shiri-Sverdlov, Ronit, Bussink, Johan, Kanneganti, Thirumala D, Boon, Mariëtte R, Stienstra, Rinke, Tack, Cees J, Rensen, Patrick CN, Netea, Mihai G, Berbée, Jimmy FP, van Diepen, Janna A
Publicado 2019

FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis

por Liu, Cong, Schönke, Milena, Spoorenberg, Borah, Lambooij, Joost M, van der Zande, Hendrik JP, Zhou, Enchen, Tushuizen, Maarten E, Andreasson, Anne-Christine, Park, Andrew, Oldham, Stephanie, Uhrbom, Martin, Ahlstedt, Ingela, Ikeda, Yasuhiro, Wallenius, Kristina, Peng, Xiao-Rong, Guigas, Bruno, Boon, Mariëtte R, Wang, Yanan, Rensen, Patrick CN
Publicado 2023

Dietary butyrate ameliorates metabolic health associated with selective proliferation of gut Lachnospiraceae bacterium 28-4

por Li, Zhuang, Zhou, Enchen, Liu, Cong, Wicks, Hope, Yildiz, Sena, Razack, Farhana, Ying, Zhixiong, Kooijman, Sander, Koonen, Debby P.Y., Heijink, Marieke, Kostidis, Sarantos, Giera, Martin, Sanders, Ingrid M.J.G., Kuijper, Ed J., Smits, Wiep Klaas, van Dijk, Ko Willems, Rensen, Patrick C.N., Wang, Yanan
Publicado 2023

Deletion of hematopoietic Dectin-2 or CARD9 does not protect against atherosclerotic plaque formation in hyperlipidemic mice

por Thiem, Kathrin, Hoeke, Geerte, van den Berg, Susan, Hijmans, Anneke, Jacobs, Cor W. M., Zhou, Enchen, Mol, Isabel M., Mouktaroudi, Maria, Bussink, Johan, Kanneganti, Thirumala D., Lutgens, Esther, Stienstra, Rinke, Tack, Cees J., Netea, Mihai G., Rensen, Patrick C. N., Berbée, Jimmy F. P., van Diepen, Janna A.
Publicado 2019