Antiviral PROTACs: Opportunity borne with challenge

por Liang, Jinsen, Wu, Yihe, Lan, Ke, Dong, Chune, Wu, Shuwen, Li, Shu, Zhou, Hai-Bing
Publicado 2023

Identification of a novel binding inhibitor that blocks the interaction between hSCARB2 and VP1 of enterovirus 71

por Tang, Qi, Xu, Zhichao, Zhang, Fan, Cai, Yang, Chen, Yinuo, Lu, Baojing, Zhou, Hai-bing, Lan, Ke, Wu, Shuwen
Publicado 2022

Selenophene and thiophene-core estrogen receptor ligands that inhibit motility and development of parasitic stages of Haemonchus contortus

por Preston, Sarah, Luo, Junjie, Zhang, Yuezhou, Jabbar, Abdul, Crawford, Simon, Baell, Jonathan, Hofmann, Andreas, Hu, Min, Zhou, Hai-Bing, Gasser, Robin B.
Publicado 2016

Discovery of oseltamivir-based novel PROTACs as degraders targeting neuraminidase to combat H1N1 influenza virus

por Xu, Zhichao, Liu, Xinjin, Ma, Xiaoyu, Zou, Wenting, Chen, Qi, Chen, Feifei, Deng, Xiaofei, Liang, Jinsen, Dong, Chune, Lan, Ke, Wu, Shuwen, Zhou, Hai-Bing
Publicado 2022

Triaryl-Substituted Schiff Bases Are High-Affinity Subtype-Selective Ligands for the Estrogen Receptor

por Liao, Zong-Quan, Dong, Chune, Carlson, Kathryn E., Srinivasan, Sathish, Nwachukwu, Jerome C., Chesnut, Robert W., Sharma, Abhishek, Nettles, Kendall W., Katzenellenbogen, John A., Zhou, Hai-Bing
Publicado 2014

Discovery of novel covalent selective estrogen receptor degraders against endocrine-resistant breast cancer

por Wang, Yubo, Min, Jian, Deng, Xiangping, Feng, Tian, Hu, Hebing, Guo, Xinyi, Cheng, Yan, Xie, Baohua, Yang, Yu, Chen, Chun-Chi, Guo, Rey-Ting, Dong, Chune, Zhou, Hai-Bing
Publicado 2023

The neuroprotective effect of bisperoxovandium (pyridin-2-squaramide) in intracerebral hemorrhage

por Liao, Xin-Yu, Lei, Yang, Chen, Song-Feng, Cheng, Jing, Zhao, Dan, Zhang, Zhi-Feng, Han, Xin, Zhang, Ya, Liao, Hua-Bao, Zhuang, Yang, Chen, Juan, Zhou, Hai-Bing, Wan, Qi, Zou, Ying-Ying
Publicado 2019

CDK12 and Integrator-PP2A complex modulates LEO1 phosphorylation for processive transcription elongation

por Qiu, Min, Yin, Zhinang, Wang, Honghong, Lei, Lingyu, Li, Conghui, Cui, Yali, Dai, Rong, Yang, Peiyuan, Xiang, Ying, Li, Qiuzi, Lv, Junhui, Hu, Zhuang, Chen, Min, Zhou, Hai-Bing, Fang, Pingping, Xiao, Ruijing, Liang, Kaiwei
Publicado 2023

Predictive features of ligand‐specific signaling through the estrogen receptor

por Nwachukwu, Jerome C, Srinivasan, Sathish, Zheng, Yangfan, Wang, Song, Min, Jian, Dong, Chune, Liao, Zongquan, Nowak, Jason, Wright, Nicholas J, Houtman, René, Carlson, Kathryn E, Josan, Jatinder S, Elemento, Olivier, Katzenellenbogen, John A, Zhou, Hai‐Bing, Nettles, Kendall W
Publicado 2016

Full Antagonism of the Estrogen Receptor without a Prototypical Ligand Side Chain

por Srinivasan, Sathish, Nwachukwu, Jerome C., Bruno, Nelson E., Dharmarajan, Venkatasubramanian, Goswami, Devrishi, Kastrati, Irida, Novick, Scott, Nowak, Jason, Cavett, Valerie, Zhou, Hai-Bing, Boonmuen, Nittaya, Zhao, Yuechao, Min, Jian, Frasor, Jonna, Katzenellenbogen, Benita S., Griffin, Patrick R., Katzenellenbogen, John A., Nettles, Kendall W.
Publicado 2016