Polygenic Score Models for Alzheimer’s Disease: From Research to Clinical Applications

por Zhou, Xiaopu, Li, Yolanda Y. T., Fu, Amy K. Y., Ip, Nancy Y.
Publicado 2021

Axin Regulates Dendritic Spine Morphogenesis through Cdc42-Dependent Signaling

por Chen, Yu, Liang, Zhuoyi, Fei, Erkang, Chen, Yuewen, Zhou, Xiaopu, Fang, Weiqun, Fu, Wing-Yu, Fu, Amy K. Y., Ip, Nancy Y.
Publicado 2015

Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer’s disease pathogenesis

por Zhou, Xiaopu, Chen, Yu, Mok, Kin Y., Zhao, Qianhua, Chen, Keliang, Chen, Yuewen, Hardy, John, Li, Yun, Fu, Amy K. Y., Guo, Qihao, Ip, Nancy Y.
Publicado 2018

Demographics and Medication Use of Patients with Late-Onset Alzheimer’s Disease in Hong Kong

por Wong, Hiu Yi, Zhong, Huan, Zhong, Mingqian, Zhou, Xiaopu, Chan, Phillip Y.C., Kwok, Timothy C.Y., Mok, Kin, Hardy, John, Ip, Fanny C.F., Fu, Amy K.Y., Ip, Nancy Y.
Publicado 2022

GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer’s disease

por Xu, Peng, Chang, Jerry C., Zhou, Xiaopu, Wang, Wei, Bamkole, Michael, Wong, Eitan, Bettayeb, Karima, Jiang, Lu-Lin, Huang, Timothy, Luo, Wenjie, Xu, Huaxi, Nairn, Angus C., Flajolet, Marc, Ip, Nancy Y., Li, Yue-Ming, Greengard, Paul
Publicado 2021

Association of SPI1 Haplotypes with Altered SPI1 Gene Expression and Alzheimer’s Disease Risk

por Cao, Han, Zhou, Xiaopu, Chen, Yu, Ip, Fanny C.F., Chen, Yuewen, Lai, Nicole C.H., Lo, Ronnie M.N., Tong, Estella P.S., Mok, Vincent C.T., Kwok, Timothy C.Y., Fu, Amy K.Y., Ip, Nancy Y.
Publicado 2022

Non-coding variability at the APOE locus contributes to the Alzheimer’s risk

por Zhou, Xiaopu, Chen, Yu, Mok, Kin Y., Kwok, Timothy C. Y., Mok, Vincent C. T., Guo, Qihao, Ip, Fanny C., Chen, Yuewen, Mullapudi, Nandita, Giusti-Rodríguez, Paola, Sullivan, Patrick F., Hardy, John, Fu, Amy K. Y., Li, Yun, Ip, Nancy Y.
Publicado 2019

Large‐scale plasma proteomic profiling identifies a high‐performance biomarker panel for Alzheimer's disease screening and staging

por Jiang, Yuanbing, Zhou, Xiaopu, Ip, Fanny C., Chan, Philip, Chen, Yu, Lai, Nicole C.H., Cheung, Kit, Lo, Ronnie M.N., Tong, Estella P.S., Wong, Bonnie W.Y., Chan, Andrew L.T., Mok, Vincent C.T., Kwok, Timothy C.Y., Mok, Kin Y., Hardy, John, Zetterberg, Henrik, Fu, Amy K.Y., Ip, Nancy Y.
Publicado 2021

Multi‐Omics‐Based Autophagy‐Related Untypical Subtypes in Patients with Cerebral Amyloid Pathology

por Park, Jong‐Chan, Barahona‐Torres, Natalia, Jang, So‐Yeong, Mok, Kin Y., Kim, Haeng Jun, Han, Sun‐Ho, Cho, Kwang‐Hyun, Zhou, Xiaopu, Fu, Amy K. Y., Ip, Nancy Y., Seo, Jieun, Choi, Murim, Jeong, Hyobin, Hwang, Daehee, Lee, Dong Young, Byun, Min Soo, Yi, Dahyun, Han, Jong Won, Mook‐Jung, Inhee, Hardy, John
Publicado 2022

Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction

por Zhou, Xiaopu, Chen, Yu, Ip, Fanny C. F., Jiang, Yuanbing, Cao, Han, Lv, Ge, Zhong, Huan, Chen, Jiahang, Ye, Tao, Chen, Yuewen, Zhang, Yulin, Ma, Shuangshuang, Lo, Ronnie M. N., Tong, Estella P. S., Mok, Vincent C. T., Kwok, Timothy C. Y., Guo, Qihao, Mok, Kin Y., Shoai, Maryam, Hardy, John, Chen, Lei, Fu, Amy K. Y., Ip, Nancy Y.
Publicado 2023

Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population

por Zhou, Xiaopu, Chen, Yu, Ip, Fanny C. F., Lai, Nicole C. H., Li, Yolanda Y. T., Jiang, Yuanbing, Zhong, Huan, Chen, Yuewen, Zhang, Yulin, Ma, Shuangshuang, Lo, Ronnie M. N., Cheung, Kit, Tong, Estella P. S., Ko, Ho, Shoai, Maryam, Mok, Kin Y., Hardy, John, Mok, Vincent C. T., Kwok, Timothy C. Y., Fu, Amy K. Y., Ip, Nancy Y.
Publicado 2020

An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease

por Jiang, Yuanbing, Zhou, Xiaopu, Wong, Hiu Yi, Ouyang, Li, Ip, Fanny C. F., Chau, Vicky M. N., Lau, Shun-Fat, Wu, Wei, Wong, Daniel Y. K., Seo, Heukjin, Fu, Wing-Yu, Lai, Nicole C. H., Chen, Yuewen, Chen, Yu, Tong, Estella P. S., Mok, Vincent C. T., Kwok, Timothy C. Y., Mok, Kin Y., Shoai, Maryam, Lehallier, Benoit, Losada, Patricia Morán, O’Brien, Eleanor, Porter, Tenielle, Laws, Simon M., Hardy, John, Wyss-Coray, Tony, Masters, Colin L., Fu, Amy K. Y., Ip, Nancy Y.
Publicado 2022