Mechanism-based Screening for Cancer Therapeutics with Examples from the Discovery of Marine Natural Product-based HIF-1 Inhibitors

por Nagle, Dale G., Zhou, Yu-Dong
Publicado 2012

Anterior Paraventricular Thalamus to Nucleus Accumbens Projection Is Involved in Feeding Behavior in a Novel Environment

por Cheng, Jingjing, Wang, Jincheng, Ma, Xiaolin, Ullah, Rahim, Shen, Yi, Zhou, Yu-Dong
Publicado 2018

Postnatal Feeding With a Fat Rich Diet Induces Precocious Puberty Independent of Body Weight, Body Fat, and Leptin Levels in Female Mice

por Ullah, Rahim, Raza, Ali, Rauf, Naveed, Shen, Yi, Zhou, Yu-Dong, Fu, Junfen
Publicado 2019

Role of Nutrition in the Pathogenesis and Prevention of Non-alcoholic Fatty Liver Disease: Recent Updates

por Ullah, Rahim, Rauf, Naveed, Nabi, Ghulam, Ullah, Hamid, Shen, Yi, Zhou, Yu-Dong, Fu, Junfen
Publicado 2019

Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy

por Zhou, Yu-Dong, Lee, Sanghoon, Jin, Zhe, Wright, Moriah, Smith, Stephen E. P., Anderson, Matthew P.
Publicado 2009

Coix Seed Oil Exerts an Anti–Triple-Negative Breast Cancer Effect by Disrupting miR-205/S1PR1 Axis

por Fang, Ting, Jiang, Yi-Xin, Chen, Long, Huang, Ling, Tian, Xin-Hui, Zhou, Yu-Dong, Nagle, Dale G., Zhang, Dan-Dan
Publicado 2020

Postnatal activation of TLR4 in astrocytes promotes excitatory synaptogenesis in hippocampal neurons

por Shen, Yi, Qin, Huaping, Chen, Juan, Mou, Lingyan, He, Yang, Yan, Yixiu, Zhou, Hang, Lv, Ya, Chen, Zhong, Wang, Junlu, Zhou, Yu-Dong
Publicado 2016

Biochemical and Anti-Triple Negative Metastatic Breast Tumor Cell Properties of Psammaplins

por Zhou, Yu-Dong, Li, Jun, Du, Lin, Mahdi, Fakhri, Le, Thuy P., Chen, Wei-Lun, Swanson, Steven M., Watabe, Kounosuke, Nagle, Dale G.
Publicado 2018

Kalkitoxin Inhibits Angiogenesis, Disrupts Cellular Hypoxic Signaling, and Blocks Mitochondrial Electron Transport in Tumor Cells

por Morgan, J. Brian, Liu, Yang, Coothankandaswamy, Veena, Mahdi, Fakhri, Jekabsons, Mika B., Gerwick, William H., Valeriote, Frederick A., Zhou, Yu-Dong, Nagle, Dale G.
Publicado 2015

Single Ethanol Withdrawal Regulates Extrasynaptic δ-GABA(A) Receptors Via PKCδ Activation

por Chen, Juan, He, Yang, Wu, Yan, Zhou, Hang, Su, Li-Da, Li, Wei-Nan, Olsen, Richard W., Liang, Jing, Zhou, Yu-Dong, Shen, Yi
Publicado 2018

Breast cancer cells that preferentially metastasize to lung or bone are more glycolytic, synthesize serine at greater rates, and consume less ATP and NADPH than parent MDA-MB-231 c...

por Jekabsons, Mika B., Merrell, Mollie, Skubiz, Anna G., Thornton, Noah, Milasta, Sandra, Green, Douglas, Chen, Taosheng, Wang, Yan-Hong, Avula, Bharathi, Khan, Ikhlas A., Zhou, Yu-Dong
Publicado 2023

The antitumor natural product tanshinone IIA inhibits protein kinase C and acts synergistically with 17-AAG

por Lv, Chao, Zeng, Hua-Wu, Wang, Jin-Xin, Yuan, Xing, Zhang, Chuang, Fang, Ting, Yang, Pei-Ming, Wu, Tong, Zhou, Yu-Dong, Nagle, Dale G., Zhang, Wei-Dong
Publicado 2018

Amyloid β oligomers suppress excitatory transmitter release via presynaptic depletion of phosphatidylinositol-4,5-bisphosphate

por He, Yang, Wei, Mengdi, Wu, Yan, Qin, Huaping, Li, Weinan, Ma, Xiaolin, Cheng, Jingjing, Ren, Jinshuai, Shen, Ye, Chen, Zhong, Sun, Binggui, Huang, Fu-De, Shen, Yi, Zhou, Yu-Dong
Publicado 2019

Increasing astrogenesis in the developing hippocampus induces autistic‐like behavior in mice via enhancing inhibitory synaptic transmission

por Chen, Juan, Ma, Xiao‐Lin, Zhao, Hui, Wang, Xiao‐Yu, Xu, Min‐Xin, Wang, Hua, Yang, Tian‐Qi, Peng, Cheng, Liu, Shuang‐Shuang, Huang, Man, Zhou, Yu‐Dong, Shen, Yi
Publicado 2021

Early treatment of minocycline alleviates white matter and cognitive impairments after chronic cerebral hypoperfusion

por Ma, Jing, Zhang, Jing, Hou, Wei Wei, Wu, Xiao Hua, Liao, Ru Jia, Chen, Ying, Wang, Zhe, Zhang, Xiang Nan, Zhang, Li San, Zhou, Yu Dong, Chen, Zhong, Hu, Wei Wei
Publicado 2015

Histidine provides long-term neuroprotection after cerebral ischemia through promoting astrocyte migration

por Liao, Ru-jia, Jiang, Lei, Wang, Rong-rong, Zhao, Hua-wei, Chen, Ying, Li, Ya, Wang, Lu, Jie, Li-Yong, Zhou, Yu-dong, Zhang, Xiang-nan, Chen, Zhong, Hu, Wei-wei
Publicado 2015

Crizotinib‐based proteolysis targeting chimera suppresses gastric cancer by promoting MET degradation

por Chen, Jin‐Jiao, Jin, Jin‐Mei, Gu, Wen‐Jie, Zhao, Zeng, Yuan, Hu, Zhou, Yu‐Dong, Nagle, Dale G., Xi, Qiu‐Lei, Zhang, Xue‐Mei, Sun, Qing‐Yan, Wu, Ye, Zhang, Wei‐Dong, Luan, Xin
Publicado 2023

Small-molecule PROTAC mediates targeted protein degradation to treat STAT3-dependent epithelial cancer

por Jin, Jinmei, Wu, Yaping, Zhao, Zeng, Wu, Ye, Zhou, Yu-dong, Liu, Sanhong, Sun, Qingyan, Yang, Guizhu, Lin, Jiayi, Nagle, Dale G., Qin, Jiangjiang, Zhang, Zhiyuan, Chen, Hong-zhuan, Zhang, Weidong, Sun, Shuyang, Luan, Xin
Publicado 2022