Quantitative translational modeling to facilitate preclinical to clinical efficacy & toxicity translation in oncology

por Zhu, Andy ZX
Publicado 2018

A Citrulline‐Based Translational Population System Toxicology Model for Gastrointestinal‐Related Adverse Events Associated With Anticancer Treatments

por Yoneyama, Tomoki, Abdul‐Hadi, Kojo, Brown, Adam, Guan, Emily, Wagoner, Matt, Zhu, Andy Z.X.
Publicado 2019

Association of CHRNA5-A3-B4 SNP rs2036527 with smoking cessation therapy response in African American smokers

por Zhu, Andy Z.X., Zhou, Qian, Cox, Lisa Sanderson, David, Sean P., Ahluwalia, Jasjit S., Benowitz, Neal L., Tyndale, Rachel F.
Publicado 2014

Recommendations for the Design of Clinical Drug–Drug Interaction Studies With Itraconazole Using a Mechanistic Physiologically‐Based Pharmacokinetic Model

por Chen, Yuan, Cabalu, Tamara D., Callegari, Ernesto, Einolf, Heidi, Liu, Lichuan, Parrott, Neil, Peters, Sheila Annie, Schuck, Edgar, Sharma, Pradeep, Tracey, Helen, Upreti, Vijay V., Zheng, Ming, Zhu, Andy Z.X., Hall, Stephen D.
Publicado 2019

Functional characterization of novel rare CYP2A6 variants and potential implications for clinical outcomes

por El‐Boraie, Ahmed, Tanner, Julie‐Anne, Zhu, Andy Z.X., Claw, Katrina G., Prasad, Bhagwat, Schuetz, Erin G., Thummel, Kenneth E., Fukunaga, Koya, Mushiroda, Taisei, Kubo, Michiaki, Benowitz, Neal L., Lerman, Caryn, Tyndale, Rachel F.
Publicado 2021

Physiologically‐Based Pharmacokinetic Modeling in Renal and Hepatic Impairment Populations: A Pharmaceutical Industry Perspective

por Heimbach, Tycho, Chen, Yuan, Chen, Jun, Dixit, Vaishali, Parrott, Neil, Peters, Sheila Annie, Poggesi, Italo, Sharma, Pradeep, Snoeys, Jan, Shebley, Mohamad, Tai, Guoying, Tse, Susanna, Upreti, Vijay V., Wang, Ying‐Hong, Tsai, Alice, Xia, Binfeng, Zheng, Ming, Zhu, Andy Z.X., Hall, Stephen
Publicado 2020

Quantitative Systems Pharmacology Approaches for Immuno‐Oncology: Adding Virtual Patients to the Development Paradigm

por Chelliah, Vijayalakshmi, Lazarou, Georgia, Bhatnagar, Sumit, Gibbs, John P., Nijsen, Marjoleen, Ray, Avijit, Stoll, Brian, Thompson, R. Adam, Gulati, Abhishek, Soukharev, Serguei, Yamada, Akihiro, Weddell, Jared, Sayama, Hiroyuki, Oishi, Masayo, Wittemer‐Rump, Sabine, Patel, Chirag, Niederalt, Christoph, Burghaus, Rolf, Scheerans, Christian, Lippert, Jörg, Kabilan, Senthil, Kareva, Irina, Belousova, Natalya, Rolfe, Alex, Zutshi, Anup, Chenel, Marylore, Venezia, Filippo, Fouliard, Sylvain, Oberwittler, Heike, Scholer‐Dahirel, Alix, Lelievre, Helene, Bottino, Dean, Collins, Sabrina C., Nguyen, Hoa Q., Wang, Haiqing, Yoneyama, Tomoki, Zhu, Andy Z.X., van der Graaf, Piet H., Kierzek, Andrzej M.
Publicado 2020