Cell cycle arrest in Metformin treated breast cancer cells involves activation of AMPK, downregulation of cyclin D1, and requires p27(Kip1 )or p21(Cip1)

por Zhuang, Yongxian, Miskimins, W Keith
Publicado 2008

Preventing feedback activation of glycolytic ATP production enhances metformin cytotoxicity in breast cancer cells when oxidative phosphorylation is inhibited

por Zhuang, Yongxian, Chan, Daniel K, Miskimins, W Keith
Publicado 2014

Mechanisms by Which Low Glucose Enhances the Cytotoxicity of Metformin to Cancer Cells Both In Vitro and In Vivo

por Zhuang, Yongxian, Chan, Daniel K., Haugrud, Allison B., Miskimins, W. Keith
Publicado 2014

Ability of metformin to deplete NAD+ contributes to cancer cell susceptibility to metformin cytotoxicity and is dependent on NAMPT expression

por Zhuang, Yongxian, Haugrud, Allison B., Schaefer, Meg A., Messerli, Shanta M., Miskimins, W. Keith
Publicado 2023

Differential roles of ERRFI1 in EGFR and AKT pathway regulation affect cancer proliferation

por Cairns, Junmei, Fridley, Brooke L, Jenkins, Gregory D, Zhuang, Yongxian, Yu, Jia, Wang, Liewei
Publicado 2018

NDUFA4L2 promotes trastuzumab resistance in HER2-positive breast cancer

por Yuan, Yuan, Gao, Huanyao, Zhuang, Yongxian, Wei, Lixuan, Yu, Jia, Zhang, Zhe, Zhang, Lili, Wang, Liewei
Publicado 2021

Use of Antimetastatic SOD3-Mimetic Albumin as a Primer in Triple Negative Breast Cancer

por Messerli, Shanta M., Schaefer, Amanda M., Zhuang, Yongxian, Soltys, Bohdan J., Keime, Noah, Jin, Jenny, Ma, Li, Hsia, Carleton J. C., Miskimins, W. Keith
Publicado 2019

The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and metformin cytotoxicity in breast cancer

por Zhuang, Yongxian, Ly, Reynold C., Frazier, Carleigh V., Yu, Jia, Qin, Sisi, Fan, Xiao-Yang, Goetz, Matthew P., Boughey, Judy C., Weinshilboum, Richard, Wang, Liewei
Publicado 2019

Oncolytic Urabe mumps virus: A promising virotherapy for triple-negative breast cancer

por Behrens, Marshall D., Stiles, Robert J., Pike, Gennett M., Sikkink, Laura A., Zhuang, Yongxian, Yu, Jia, Wang, Liewei, Boughey, Judy C., Goetz, Matthew P., Federspiel, Mark J.
Publicado 2022

Identification of Src Family Kinases as Potential Therapeutic Targets for Chemotherapy-Resistant Triple Negative Breast Cancer

por Kohale, Ishwar N., Yu, Jia, Zhuang, Yongxian, Fan, Xiaoyang, Reddy, Raven J., Sinnwell, Jason, Kalari, Krishna R., Boughey, Judy C., Carter, Jodi M., Goetz, Matthew P., Wang, Liewei, White, Forest M.
Publicado 2022

Establishment and characterization of immortalized human breast cancer cell lines from breast cancer patient-derived xenografts (PDX)

por Zhuang, Yongxian, Grainger, Jordan M., Vedell, Peter T., Yu, Jia, Moyer, Ann M., Gao, Huanyao, Fan, Xiao-Yang, Qin, Sisi, Liu, Duan, Kalari, Krishna R., Goetz, Matthew P., Boughey, Judy C., Weinshilboum, Richard M., Wang, Liewei
Publicado 2021

Biomarkers for Predicting Abiraterone Treatment Outcome and Selecting Alternative Therapies in Castration‐Resistant Prostate Cancer

por Qin, Sisi, Gao, Huanyao, Kim, Wootae, Zhang, Huan, Gu, Yayun, Kalari, Krishna R., Sinnwell, Jason P., Scholz, Jodi A., Xie, Fang, Yin, Ping, Yu, Jia, Qin, Bo, Zhuang, Yongxian, Wei, Lixuan, Tan, Winston, Bryce, Alan H., Weinshilboum, Richard M., Wang, Liewei
Publicado 2022

TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration

por Xie, Manling, Liu, Yong U., Zhao, Shunyi, Zhang, Lingxin, Bosco, Dale B., Pang, Yuan-Ping, Zhong, Jun, Sheth, Udit, Martens, Yuka A., Zhao, Na, Liu, Chia-Chen, Zhuang, Yongxian, Wang, Liewei, Dickson, Dennis W., Mattson, Mark P., Bu, Guojun, Wu, Long-Jun
Publicado 2021

ERICH3: vesicular association and antidepressant treatment response

por Liu, Duan, Zhuang, Yongxian, Zhang, Lingxin, Gao, Huanyao, Neavin, Drew, Carrillo-Roa, Tania, Wang, Yani, Yu, Jia, Qin, Sisi, Kim, Daniel C., Liu, Erica, Nguyen, Thanh Thanh Le, Biernacka, Joanna M., Kaddurah-Daouk, Rima, Dunlop, Boadie W., Craighead, W. Edward, Mayberg, Helen S., Binder, Elisabeth B., Frye, Mark A., Wang, Liewei, Weinshilboum, Richard M.
Publicado 2020

Anastrozole Aromatase Inhibitor Plasma Drug Concentration Genome‐Wide Association Study: Functional Epistatic Interaction Between SLC38A7 and ALPPL2

por Dudenkov, Tanda M., Liu, Duan, Cairns, Junmei, Devarajan, Sandhya, Zhuang, Yongxian, Ingle, James N., Buzdar, Aman U., Robson, Mark E., Kubo, Michiaki, Batzler, Anthony, Barman, Poulami, Jenkins, Gregory D., Carlson, Erin E., Goetz, Matthew P., Northfelt, Donald W., Moreno‐Aspitia, Alvaro, Desta, Zeruesenay, Reid, Joel M., Kalari, Krishna R., Wang, Liewei, Weinshilboum, Richard M.
Publicado 2019