Mitophagy in Astrocytes Is Required for the Health of Optic Nerve

por Yazdankhah, Meysam, Ghosh, Sayan, Liu, Haitao, Hose, Stacey, Zigler, J. Samuel, Sinha, Debasish
Publicado 2023

Aberrant Akt2 signaling in the RPE may contribute to retinal fibrosis process in diabetic retinopathy

por Daley, Rachel, Maddipatla, Vishnu, Ghosh, Sayan, Chowdhury, Olivia, Hose, Stacey, Zigler, J. Samuel, Sinha, Debasish, Liu, Haitao
Publicado 2023

The role of lipocalin-2 in age-related macular degeneration (AMD)

por Ghosh, Sayan, Stepicheva, Nadezda, Yazdankhah, Meysam, Shang, Peng, Watson, Alan M., Hose, Stacey, Liu, Haitao, Weiss, Joseph, Zigler, J. Samuel, Valapala, Mallika, Watkins, Simon C., Sinha, Debasish
Publicado 2020

A Novel Method of Mouse RPE Explant Culture and Effective Introduction of Transgenes Using Adenoviral Transduction for In Vitro Studies in AMD

por Shang, Peng, Stepicheva, Nadezda A., Liu, Haitao, Chowdhury, Olivia, Franks, Jonathan, Sun, Ming, Hose, Stacey, Ghosh, Sayan, Yazdankhah, Meysam, Strizhakova, Anastasia, Stolz, Donna Beer, Zigler, J. Samuel, Sinha, Debasish
Publicado 2021

A Role for βA3/A1-Crystallin in Type 2 EMT of RPE Cells Occurring in Dry Age-Related Macular Degeneration

por Ghosh, Sayan, Shang, Peng, Terasaki, Hiroto, Stepicheva, Nadezda, Hose, Stacey, Yazdankhah, Meysam, Weiss, Joseph, Sakamoto, Taiji, Bhutto, Imran A., Xia, Shuli, Zigler, J. Samuel, Kannan, Ram, Qian, Jiang, Handa, James T., Sinha, Debasish
Publicado 2018

Microglia–Neutrophil Interactions Drive Dry AMD-like Pathology in a Mouse Model

por Boyce, Maeve, Xin, Ying, Chowdhury, Olivia, Shang, Peng, Liu, Haitao, Koontz, Victoria, Strizhakova, Anastasia, Nemani, Mihir, Hose, Stacey, Zigler, J. Samuel, Campbell, Matthew, Sinha, Debasish, Handa, James T., Kaarniranta, Kai, Qian, Jiang, Ghosh, Sayan
Publicado 2022

The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling

por Shang, Peng, Valapala, Mallika, Grebe, Rhonda, Hose, Stacey, Ghosh, Sayan, Bhutto, Imran A., Handa, James T., Lutty, Gerard A., Lu, Lixia, Wan, Jun, Qian, Jiang, Sergeev, Yuri, Puertollano, Rosa, Zigler, J. Samuel, Xu, Guo‐Tong, Sinha, Debasish
Publicado 2017

A Spontaneous Missense Mutation in Branched Chain Keto Acid Dehydrogenase Kinase in the Rat Affects Both the Central and Peripheral Nervous Systems

por Zigler, J. Samuel, Hodgkinson, Colin A., Wright, Megan, Klise, Andrew, Sundin, Olof, Broman, Karl W., Hejtmancik, Fielding, Huang, Hao, Patek, Bonnie, Sergeev, Yuri, Hose, Stacey, Brayton, Cory, Xaiodong, Jiao, Vasquez, David, Maragakis, Nicholas, Mori, Susumu, Goldman, David, Hoke, Ahmet, Sinha, Debasish
Publicado 2016

Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy

por Liu, Haitao, Stepicheva, Nadezda A., Ghosh, Sayan, Shang, Peng, Chowdhury, Olivia, Daley, Rachel A., Yazdankhah, Meysam, Gupta, Urvi, Hose, Stacey L., Valapala, Mallika, Fitting, Christopher Scott, Strizhakova, Anastasia, Shan, Yang, Feenstra, Derrick, Sahel, José-Alain, Jayagopal, Ashwath, Handa, James T., Zigler, J. Samuel, Fort, Patrice E., Sodhi, Akrit, Sinha, Debasish
Publicado 2022

Neutrophils homing into the retina trigger pathology in early age-related macular degeneration

por Ghosh, Sayan, Padmanabhan, Archana, Vaidya, Tanuja, Watson, Alan M., Bhutto, Imran A., Hose, Stacey, Shang, Peng, Stepicheva, Nadezda, Yazdankhah, Meysam, Weiss, Joseph, Das, Manjula, Gopikrishna, Santosh, Aishwarya, Yadav, Naresh, Berger, Thorsten, Mak, Tak W., Xia, Shuli, Qian, Jiang, Lutty, Gerard A., Jayagopal, Ashwath, Zigler, J. Samuel, Sethu, Swaminathan, Handa, James T., Watkins, Simon C., Ghosh, Arkasubhra, Sinha, Debasish
Publicado 2019

Activated cGAS/STING signaling elicits endothelial cell senescence in early diabetic retinopathy

por Liu, Haitao, Ghosh, Sayan, Vaidya, Tanuja, Bammidi, Sridhar, Huang, Chao, Shang, Peng, Nair, Archana Padmanabhan, Chowdhury, Olivia, Stepicheva, Nadezda A., Strizhakova, Anastasia, Hose, Stacey, Mitrousis, Nikolaos, Gadde, Santosh Gopikrishna, MB, Thirumalesh, Strassburger, Pamela, Widmer, Gabriella, Lad, Eleonora M., Fort, Patrice E., Sahel, José-Alain, Zigler, J. Samuel, Sethu, Swaminathan, Westenskow, Peter D., Proia, Alan D., Sodhi, Akrit, Ghosh, Arkasubhra, Feenstra, Derrick, Sinha, Debasish
Publicado 2023

βA1-crystallin regulates glucose metabolism and mitochondrial function in mouse retinal astrocytes by modulating PTP1B activity

por Ghosh, Sayan, Liu, Haitao, Yazdankhah, Meysam, Stepicheva, Nadezda, Shang, Peng, Vaidya, Tanuja, Hose, Stacey, Gupta, Urvi, Calderon, Michael Joseph, Hu, Ming-Wen, Nair, Archana Padmanabhan, Weiss, Joseph, Fitting, Christopher S., Bhutto, Imran A., Gadde, Santosh Gopi Krishna, Naik, Naveen Kumar, Jaydev, Chaitra, Lutty, Gerard A., Handa, James T., Jayagopal, Ashwath, Qian, Jiang, Sahel, José-Alain, Rajasundaram, Dhivyaa, Sergeev, Yuri, Zigler, J. Samuel, Sethu, Swaminathan, Watkins, Simon, Ghosh, Arkasubhra, Sinha, Debasish
Publicado 2021