Adenylosuccinate lyase deficiency

por Jurecka, Agnieszka, Zikanova, Marie, Kmoch, Stanislav, Tylki-Szymańska, Anna
Publicado 2014

Study of purinosome assembly in cell-based model systems with de novo purine synthesis and salvage pathway deficiencies

por Baresova, Veronika, Skopova, Vaclava, Souckova, Olga, Krijt, Matyas, Kmoch, Stanislav, Zikanova, Marie
Publicado 2018

Metabolites of De Novo Purine Synthesis: Metabolic Regulators and Cytotoxic Compounds

por Souckova, Olga, Skopova, Vaclava, Baresova, Veronika, Sedlak, David, Bleyer, Anthony J., Kmoch, Stanislav, Zikanova, Marie
Publicado 2022

The CRISPR-Cas9 crADSL HeLa transcriptome: A first step in establishing a model for ADSL deficiency and SAICAR accumulation

por Mazzarino, Randall C., Baresova, Veronika, Zikánová, Marie, Duval, Nathan, Wilkinson, Terry G., Patterson, David, Vacano, Guido N.
Publicado 2019

The CRISPR-Cas9 crATIC HeLa transcriptome: Characterization of a novel cellular model of ATIC deficiency and ZMP accumulation

por Mazzarino, Randall C., Baresova, Veronika, Zikánová, Marie, Duval, Nathan, Wilkinson, Terry G., Patterson, David, Vacano, Guido N.
Publicado 2020

Transcriptome and metabolome analysis of crGART, a novel cell model of de novo purine synthesis deficiency: Alterations in CD36 expression and activity

por Mazzarino, Randall C., Baresova, Veronika, Zikánová, Marie, Duval, Nathan, Wilkinson, Terry G., Patterson, David, Vacano, Guido N.
Publicado 2021

Mass spectrometric analysis of purine de novo biosynthesis intermediates

por Mádrová, Lucie, Krijt, Matyáš, Barešová, Veronika, Václavík, Jan, Friedecký, David, Dobešová, Dana, Součková, Olga, Škopová, Václava, Adam, Tomáš, Zikánová, Marie
Publicado 2018

Combined Targeted and Untargeted Profiling of HeLa Cells Deficient in Purine De Novo Synthesis

por Mádrová, Lucie, Součková, Olga, Brumarová, Radana, Dobešová, Dana, Václavík, Jan, Kouřil, Štěpán, de Sousa, Julie, Friedecká, Jaroslava, Friedecký, David, Barešová, Veronika, Zikánová, Marie, Adam, Tomáš
Publicado 2022

Pathway-specific effects of ADSL deficiency on neurodevelopment

por Dutto, Ilaria, Gerhards, Julian, Herrera, Antonio, Souckova, Olga, Škopová, Václava, Smak, Jordann A, Junza, Alexandra, Yanes, Oscar, Boeckx, Cedric, Burkhalter, Martin D, Zikánová, Marie, Pons, Sebastian, Philipp, Melanie, Lüders, Jens, Stracker, Travis H
Publicado 2022

Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer

por Zurlo, Giada, Liu, Xijuan, Takada, Mamoru, Fan, Cheng, Simon, Jeremy M., Ptacek, Travis S., Rodriguez, Javier, von Kriegsheim, Alex, Liu, Juan, Locasale, Jason W., Robinson, Adam, Zhang, Jing, Holler, Jessica M., Kim, Baek, Zikánová, Marie, Bierau, Jörgen, Xie, Ling, Chen, Xian, Li, Mingjie, Perou, Charles M., Zhang, Qing
Publicado 2019