Animal models of SARS-CoV-2 and COVID-19 for the development of prophylactic and therapeutic interventions

por Renn, Marcel, Bartok, Eva, Zillinger, Thomas, Hartmann, Gunther, Behrendt, Rayk
Publicado 2021

An epigenetic GPI anchor defect impairs TLR4 signaling in the B cell transdifferentiation model for primary human monocytes BLaER1

por Wegner, Julia, Zillinger, Thomas, Schlee-Guimaraes, Thais Marina, Bartok, Eva, Schlee, Martin
Publicado 2021

Author Correction: An epigenetic GPI anchor defect impairs TLR4 signaling in the B cell transdifferentiation model for primary human monocytes BLaER1

por Wegner, Julia, Zillinger, Thomas, Schlee-Guimaraes, Thais Marina, Bartok, Eva, Schlee, Martin
Publicado 2021

G-rich DNA-induced stress response blocks type-I-IFN but not CXCL10 secretion in monocytes

por Herzner, Anna-Maria, Wolter, Steven, Zillinger, Thomas, Schmitz, Saskia, Barchet, Winfried, Hartmann, Gunther, Bartok, Eva, Schlee, Martin
Publicado 2016

Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA

por Gao, Pu, Zillinger, Thomas, Wang, Weiyi, Ascano, Manuel, Dai, Peihong, Hartmann, Gunther, Tuschl, Thomas, Deng, Liang, Barchet, Winfried, Patel, Dinshaw J.
Publicado 2014

Expression of a Functional Mx1 Protein Is Essential for the Ability of RIG-I Agonist Prophylaxis to Provide Potent and Long-Lasting Protection in a Mouse Model of Influenza A Virus...

por Schwab, Lara S. U., Villalón-Letelier, Fernando, Tessema, Melkamu B., Londrigan, Sarah L., Brooks, Andrew G., Hurt, Aeron, Coch, Christoph, Zillinger, Thomas, Hartmann, Gunther, Reading, Patrick C.
Publicado 2022

RIG-I Detects Triphosphorylated RNA of Listeria monocytogenes during Infection in Non-Immune Cells

por Hagmann, Cristina Amparo, Herzner, Anna Maria, Abdullah, Zeinab, Zillinger, Thomas, Jakobs, Christopher, Schuberth, Christine, Coch, Christoph, Higgins, Paul G., Wisplinghoff, Hilmar, Barchet, Winfried, Hornung, Veit, Hartmann, Gunther, Schlee, Martin
Publicado 2013

Retinoic Acid–Inducible Gene I Activation Inhibits Human Respiratory Syncytial Virus Replication in Mammalian Cells and in Mouse and Ferret Models of Infection

por Schwab, Lara S U, Farrukee, Rubaiyea, Eléouët, Jean-François, Rameix-Welti, Marie-Anne, Londrigan, Sarah L, Brooks, Andrew G, Hurt, Aeron C, Coch, Christoph, Zillinger, Thomas, Hartmann, Gunther, Reading, Patrick C
Publicado 2022

Human TLR8 Senses RNA From Plasmodium falciparum-Infected Red Blood Cells Which Is Uniquely Required for the IFN-γ Response in NK Cells

por Coch, Christoph, Hommertgen, Benjamin, Zillinger, Thomas, Daßler-Plenker, Juliane, Putschli, Bastian, Nastaly, Maximilian, Kümmerer, Beate M., Scheunemann, Johanna F., Schumak, Beatrix, Specht, Sabine, Schlee, Martin, Barchet, Winfried, Hoerauf, Achim, Bartok, Eva, Hartmann, Gunther
Publicado 2019

Human IFITM3 restricts chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction

por Franz, Sergej, Pott, Fabian, Zillinger, Thomas, Schüler, Christiane, Dapa, Sandra, Fischer, Carlo, Passos, Vânia, Stenzel, Saskia, Chen, Fangfang, Döhner, Katinka, Hartmann, Gunther, Sodeik, Beate, Pessler, Frank, Simmons, Graham, Drexler, Jan Felix, Goffinet, Christine
Publicado 2021

Characterization of Endogenous SERINC5 Protein as Anti-HIV-1 Factor

por Passos, Vânia, Zillinger, Thomas, Casartelli, Nicoletta, Wachs, Amelie S., Xu, Shuting, Malassa, Angelina, Steppich, Katja, Schilling, Hildegard, Franz, Sergej, Todt, Daniel, Steinmann, Eike, Sutter, Kathrin, Dittmer, Ulf, Bohne, Jens, Schwartz, Olivier, Barchet, Winfried, Goffinet, Christine
Publicado 2019

SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue

por Kmiec, Dorota, Akbil, Bengisu, Ananth, Swetha, Hotter, Dominik, Sparrer, Konstantin M. J., Stürzel, Christina M., Trautz, Birthe, Ayouba, Ahidjo, Peeters, Martine, Yao, Zhong, Stagljar, Igor, Passos, Vânia, Zillinger, Thomas, Goffinet, Christine, Sauter, Daniel, Fackler, Oliver T., Kirchhoff, Frank
Publicado 2018

Absence of cGAS-mediated type I IFN responses in HIV-1–infected T cells

por Elsner, Carina, Ponnurangam, Aparna, Kazmierski, Julia, Zillinger, Thomas, Jansen, Jenny, Todt, Daniel, Döhner, Katinka, Xu, Shuting, Ducroux, Aurélie, Kriedemann, Nils, Malassa, Angelina, Larsen, Pia-Katharina, Hartmann, Gunther, Barchet, Winfried, Steinmann, Eike, Kalinke, Ulrich, Sodeik, Beate, Goffinet, Christine
Publicado 2020

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates

por Goubau, Delphine, Schlee, Martin, Deddouche, Safia, Pruijssers, Andrea J., Zillinger, Thomas, Goldeck, Marion, Schuberth, Christine, Van der Veen, Annemarthe G., Fujimura, Tsutomu, Rehwinkel, Jan, Iskarpatyoti, Jason A., Barchet, Winfried, Ludwig, Janos, Dermody, Terence S., Hartmann, Gunther, Reis e Sousa, Caetano
Publicado 2014

A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA

por de Regt, Ann Kristin, Anand, Kanchan, Ciupka, Katrin, Bender, Felix, Gatterdam, Karl, Putschli, Bastian, Fusshöller, David, Hilbig, Daniel, Kirchhoff, Alexander, Hunkler, Charlotte, Wolter, Steven, Grünewald, Agathe, Wallerath, Christina, Schuberth-Wagner, Christine, Ludwig, Janos, Paeschke, Katrin, Bartok, Eva, Hagelueken, Gregor, Hartmann, Gunther, Zillinger, Thomas, Geyer, Matthias, Schlee, Martin
Publicado 2023

A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N(1)-2′O-Methylated Self RNA

por Schuberth-Wagner, Christine, Ludwig, Janos, Bruder, Ann Kristin, Herzner, Anna-Maria, Zillinger, Thomas, Goldeck, Marion, Schmidt, Tobias, Schmid-Burgk, Jonathan L., Kerber, Romy, Wolter, Steven, Stümpel, Jan-Philip, Roth, Andreas, Bartok, Eva, Drosten, Christian, Coch, Christoph, Hornung, Veit, Barchet, Winfried, Kümmerer, Beate M., Hartmann, Gunther, Schlee, Martin
Publicado 2015

Recessive NLRC4-Autoinflammatory Disease Reveals an Ulcerative Colitis Locus

por Steiner, Annemarie, Reygaerts, Thomas, Pontillo, Alessandra, Ceccherini, Isabella, Moecking, Jonas, Moghaddas, Fiona, Davidson, Sophia, Caroli, Francesco, Grossi, Alice, Castro, Fabio Fernandes Morato, Kalil, Jorge, Gohr, Florian N., Schmidt, Florian I., Bartok, Eva, Zillinger, Thomas, Hartmann, Gunther, Geyer, Matthias, Gattorno, Marco, Mendonça, Leonardo Oliveira, Masters, Seth L.
Publicado 2021

Deficiency in coatomer complex I causes aberrant activation of STING signalling

por Steiner, Annemarie, Hrovat-Schaale, Katja, Prigione, Ignazia, Yu, Chien-Hsiung, Laohamonthonkul, Pawat, Harapas, Cassandra R., Low, Ronnie Ren Jie, De Nardo, Dominic, Dagley, Laura F., Mlodzianoski, Michael J., Rogers, Kelly L., Zillinger, Thomas, Hartmann, Gunther, Gantier, Michael P., Gattorno, Marco, Geyer, Matthias, Volpi, Stefano, Davidson, Sophia, Masters, Seth L.
Publicado 2022

Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner

por Schumann, Tina, Ramon, Santiago Costas, Schubert, Nadja, Mayo, Mohamad Aref, Hega, Melanie, Maser, Katharina Isabell, Ada, Servi-Remzi, Sydow, Lukas, Hajikazemi, Mona, Badstübner, Markus, Müller, Patrick, Ge, Yan, Shakeri, Farhad, Buness, Andreas, Rupf, Benjamin, Lienenklaus, Stefan, Utess, Barbara, Muhandes, Lina, Haase, Michael, Rupp, Luise, Schmitz, Marc, Gramberg, Thomas, Manel, Nicolas, Hartmann, Gunther, Zillinger, Thomas, Kato, Hiroki, Bauer, Stefan, Gerbaulet, Alexander, Paeschke, Katrin, Roers, Axel, Behrendt, Rayk
Publicado 2022

Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing

por Kessler, Nina, Viehmann, Susanne F., Krollmann, Calvin, Mai, Karola, Kirschner, Katharina M., Luksch, Hella, Kotagiri, Prasanti, Böhner, Alexander M.C., Huugen, Dennis, de Oliveira Mann, Carina C., Otten, Simon, Weiss, Stefanie A.I., Zillinger, Thomas, Dobrikova, Kristiyana, Jenne, Dieter E., Behrendt, Rayk, Ablasser, Andrea, Bartok, Eva, Hartmann, Gunther, Hopfner, Karl-Peter, Lyons, Paul A., Boor, Peter, Rösen-Wolff, Angela, Teichmann, Lino L., Heeringa, Peter, Kurts, Christian, Garbi, Natalio
Publicado 2022