A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis (ALS)

por Yunusova, Yana, Green, Jordan R., Wang, Jun, Pattee, Gary, Zinman, Lorne
Publicado 2011

Breached Barriers: A Scoping Review of Blood-Central Nervous System Barrier Pathology in Amyotrophic Lateral Sclerosis

por Mirian, Ario, Moszczynski, Alexander, Soleimani, Serena, Aubert, Isabelle, Zinman, Lorne, Abrahao, Agessandro
Publicado 2022

Retinal Spheroids and Axon Pathology Identified in Amyotrophic Lateral Sclerosis

por Sharma, Kieran, Amin Mohammed Amin, Maryam, Gupta, Neeru, Zinman, Lorne, Zhou, Xun, Irving, Hyacinth, Yücel, Yeni
Publicado 2020

Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death

por Xiao, Shangxi, Sanelli, Teresa, Chiang, Helen, Sun, Yulong, Chakrabartty, Avijit, Keith, Julia, Rogaeva, Ekaterina, Zinman, Lorne, Robertson, Janice
Publicado 2015

Bulbar and speech motor assessment in ALS: Challenges and future directions

por Green, Jordan R., Yunusova, Yana, Kuruvilla, Mili S., Wang, Jun, Pattee, Gary L., Synhorst, Lori, Zinman, Lorne, Berry, James D.
Publicado 2013

Predicting Speech Intelligibility Decline in Amyotrophic Lateral Sclerosis Based on the Deterioration of Individual Speech Subsystems

por Rong, Panying, Yunusova, Yana, Wang, Jun, Zinman, Lorne, Pattee, Gary L., Berry, James D., Perry, Bridget, Green, Jordan R.
Publicado 2016

UNDERSTANDING SEX DIFFERENCES IN OLDER PERSONS WITH NEURODEGENERATIVE DISEASES

por Campitelli, Michael A, Maclagan, Laura C, Diong, Christina, Fu, Longdi, Yu, Amy Y, Zinman, Lorne, Swartz, Rick, Bronskill, Susan E
Publicado 2019

CHALLENGES IN IDENTIFYING PERSONS WITH NEURODEGENERATIVE DISEASES USING HEALTH ADMINISTRATIVE DATABASES

por Maclagan, Laura C, Soleimani, Serena, Abrahao, Agessandro, Zinman, Lorne, Campitelli, Michael A, Jaakkimainen, Liisa, Maxwell, Colleen J, Bronskill, Susan E
Publicado 2019

Somatic expansion of the C9orf72 hexanucleotide repeat does not occur in ALS spinal cord tissues

por Ross, Jay P., Leblond, Claire S., Catoire, Hélène, Volkening, Kathryn, Strong, Michael, Zinman, Lorne, Robertson, Janice, Dion, Patrick A., Rouleau, Guy A.
Publicado 2019

Involvement of the dentate nucleus in the pathophysiology of amyotrophic lateral sclerosis: A multi-center and multi-modal neuroimaging study

por Bharti, Komal, Khan, Muhammad, Beaulieu, Christian, Graham, Simon J., Briemberg, Hannah, Frayne, Richard, Genge, Angela, Korngut, Lawrence, Zinman, Lorne, Kalra, Sanjay
Publicado 2020

Cerebral atrophy in amyotrophic lateral sclerosis parallels the pathological distribution of TDP43

por Dadar, Mahsa, Manera, Ana Laura, Zinman, Lorne, Korngut, Lawrence, Genge, Angela, Graham, Simon J, Frayne, Richard, Collins, D Louis, Kalra, Sanjay
Publicado 2020

DNA methylation age-acceleration is associated with disease duration and age at onset in C9orf72 patients

por Zhang, Ming, Tartaglia, Maria Carmela, Moreno, Danielle, Sato, Christine, McKeever, Paul, Weichert, Anna, Keith, Julia, Robertson, Janice, Zinman, Lorne, Rogaeva, Ekaterina
Publicado 2017

Frontal Anatomical Correlates of Cognitive and Speech Motor Deficits in Amyotrophic Lateral Sclerosis

por Yunusova, Yana, Ansari, Jamal, Ramirez, Joel, Shellikeri, Sanjana, Stanisz, Greg J., Black, Sandra E., Gillingham, Susan M., Kiss, Alex, Stuss, Donald T., Zinman, Lorne
Publicado 2019

Neuropathologic description of CHCHD10 mutated amyotrophic lateral sclerosis

por Keith, Julia L., Swinkin, Emily, Gao, Andrew, Alminawi, Samira, Zhang, Ming, McGoldrick, Philip, McKeever, Paul, Robertson, Janice, Rogaeva, Ekaterina, Zinman, Lorne
Publicado 2020

Combined epigenetic/genetic study identified an ALS age of onset modifier

por Zhang, Ming, Xi, Zhengrui, Saez-Atienzar, Sara, Chia, Ruth, Moreno, Danielle, Sato, Christine, Montazer Haghighi, Mahdi, Traynor, Bryan J., Zinman, Lorne, Rogaeva, Ekaterina
Publicado 2021

Protocol for psychometric evaluation of the Amyotrophic Lateral Sclerosis - Bulbar Dysfunction Index (ALS-BDI): a prospective longitudinal study

por Yunusova, Yana, Waito, Ashley, Barnett, Carolina, Huynh, Anna, Martino, Rosemary, Abrahao, Agessandro, Pattee, Gary L, Berry, James D, Zinman, Lorne, Green, Jordan R
Publicado 2022

The FUS gene is dual‐coding with both proteins contributing to FUS‐mediated toxicity

por Brunet, Marie A, Jacques, Jean‐Francois, Nassari, Sonya, Tyzack, Giulia E, McGoldrick, Philip, Zinman, Lorne, Jean, Steve, Robertson, Janice, Patani, Rickie, Roucou, Xavier
Publicado 2020

Face and content validation of the amyotrophic lateral sclerosis—Bulbar dysfunction index (ALS-BDI)

por Yunusova, Yana, Waito, Ashley, Barnett Tapia, Carolina, Huynh, Anna, Martino, Rosemary, Abrahao, Agessandro, Pattee, Gary L., Berry, James D., Zinman, Lorne, Green, Jordan R.
Publicado 2023

First-in-human trial of blood–brain barrier opening in amyotrophic lateral sclerosis using MR-guided focused ultrasound

por Abrahao, Agessandro, Meng, Ying, Llinas, Maheleth, Huang, Yuexi, Hamani, Clement, Mainprize, Todd, Aubert, Isabelle, Heyn, Chinthaka, Black, Sandra E., Hynynen, Kullervo, Lipsman, Nir, Zinman, Lorne
Publicado 2019

DNA methylation age acceleration is associated with ALS age of onset and survival

por Zhang, Ming, McKeever, Paul M., Xi, Zhengrui, Moreno, Danielle, Sato, Christine, Bergsma, Tessa, McGoldrick, Philip, Keith, Julia, Robertson, Janice, Zinman, Lorne, Rogaeva, Ekaterina
Publicado 2020